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Nuclear War in the Middle East
Iran’s Supreme Leader Ayatollah Ali Khamenei visits the Iranian centrifuges in Tehran, Iran, June 11, 2023. Photo: Office of the Iranian Supreme Leader/WANA (West Asia News Agency) via REUTERS
Contrary to conventional wisdom, Israel’s “Iran nuclear problem” is not principally about enemy leaders who might go mad. The more worrisome existential problem for Israel is sane, rational enemies who experience miscalculation, poor reasoning or mechanical/electrical/computer malfunction. Other nuclear hazards that could coincide with Iranian sanity and rationality include accidental firing, unauthorized launch and coup d’état.
While it is true that decisions made by a mad Iranian nuclear adversary could have catastrophic consequences for Israel (even, indeed, by a mad pre-nuclear Iran), the likelihood of such decisions is lower than what could be expected of a sane and rational Iranian enemy. Because a nuclear war would be a unique event, such a likelihood cannot be expressed numerically or statistically but is still supportable by analytic argument.
Logic-based calculations suggest that the dispersion of nuclear dangers among multiple Iranian decisionmakers would be more perilous for Israel than the threat posed by a single authoritative Iranian leader who is mad or irrational. Here, madness and irrationality would include Iranian decisionmakers driven by jihadist theologies and principles.
In all circumstances, whether the greater danger to Israel is Iranian decisional madness or Iranian decisional sanity, Jerusalem must stay mindful of a possible “black swan” event. This need will be much greater if Iran is allowed to become a nuclear weapons state. Even at this late date, Israel should remain preemption-ready.
For Jerusalem, there are also time-urgent geopolitical considerations. Iran is approaching nuclear weapons capability concurrently with the acceleration by its jihadist proxies – Hezbollah, Hamas, the Houthis, Islamic Jihad and Fatah – of terrorist crimes against Israel. Iran, which is steadily expanding its ties with Russia, China and North Korea, repeatedly declares its genocidal intentions toward Israel. And Israel is a state with no “strategic depth.”
Prima facie, Middle Eastern geopolitics are a system. Potentially related scenarios of superpower conflict may be dense or even opaque, but they remain relevant. Among other things, the continuously changing iterations of “Cold War II” could embrace international conflicts that involve Israel with North Korea, China, India or Pakistan. Such a dangerous embrace could be sudden or incremental.
For Israel to proceed purposefully, some primary and subsidiary distinctions need further clarification. One concerns the vital differences between a deliberate or intentional nuclear war and a nuclear war that is unintentional or inadvertent. Without considering this distinction, little of value can be determined about the likelihood of a nuclear conflict.
The greatest dangers of an unintentional nuclear war are decision-making errors, underestimations or overestimations of enemy intent, or simple miscalculations. As classical military theorist Carl von Clausewitz observed, “Everything is very simple in war, but even the simplest thing is difficult.”
There are other nuances to be considered. With regard to growing nuclear war risks in the Middle East, no concept could prove more clarifying than “synergy”. Synergistic interactions are those wherein the whole of nuclear war risk effects is greater than the sum of its parts. Unless such interactions are accurately assessed and evaluated in time, Israeli leaders could either underestimate or overestimate the cumulative impact of superpower competition on risk-taking. This suggests circumstances in which Russia and the United States (and perhaps China) struggle for escalation dominance in extremis – that is, during high-value crisis situations.
In the United States, allegedly reliable safeguards have been incorporated from the beginning into all operational nuclear command/control decisions. These safeguards do not apply, however, at the presidential level. In 1976, to gather informed policy clarifications regarding madness, irrationality and nuclear war, I reached out to retired General Maxwell D. Taylor, a former Chairman of the US Joint Chiefs of Staff. General Taylor sent a handwritten reply in which he concluded: “As to those dangers arising from an irrational American president, the only protection is not to elect one.”
In today’s convulsive world order, General Taylor’s succinct 1976 warning takes on even greater meaning. Based on both ascertainable facts and logic-based derivations, it is reasonable to assume that if an American president were to exhibit signs of emotional instability, irrationality or “mad” behavior, he/she could still lawfully order the use of American nuclear weapons. More worrisome, an American, Russian or Chinese president could become emotionally unstable, irrational or delusional, but not conspicuously exhibit such liabilities.
In all matters concerning nuclear war in the Middle East, there exist no histories from which to draw inferences. This is a fortunate absence, of course, but it still stands in the way of rendering reliable conflict predictions. The irony of this situation is obvious and problematic. Still, whatever the science-based obstacles to reliable prediction in this explosive region, Israel should approach the problem as an intellectual rather than a political challenge.
It must always be remembered that a nuclear war in the Middle East could occur as a spillover effect of nuclear war in Europe. To protect Israel’s survival, an American president should avoid strategic postures that neglect potential synergies with Russian, Chinese and/or North Korean postures. North Korea is a nuclear ally of Iran that built a nuclear reactor for Syria – the Al Kibar reactor, which was destroyed by Israel’s Operation Orchard on September 6, 2007. In law, that operation was a permissible act of anticipatory self-defense.
Strategist Herman Kahn wrote in the early 1960s that in the aftermath of a nuclear conflict, “survivors might envy the dead”. This is true whether the catastrophe was intentional or unintentional – in other words, whether it was spawned by base motives or by miscalculation, computer error, hacking, or a weapon system or infrastructure accident. Whatever else can be determined by Israel’s national security decisionmakers, they should understand that nuclear strategy is ultimately a high-stakes struggle between intentionality, uncertainty and calamity. Even if both Israel and a newly nuclear Iran were to undertake “sane” risk-taking measures during a crisis, the cumulative effect could still be mutually unwanted and “mad.”
For Israel, the only successful outcome of protracted military conflict with Iran would be a tangible reduction of Iran’s nuclear war-fighting capabilities and intentions. Optimally, this point will be understood and operationalized while Iran is still pre-nuclear.
Once it is at war with either a nuclear Iran or a pre-nuclear Iran with a willing nuclear proxy (e.g., North Korea), Israel could be mortally wounded by rational decisions made by sane enemy leaders. Even now, though Iran is not yet nuclear, it could use radiation dispersal weapons against the Jewish State and/or launch non-nuclear missiles at Israel’s Dimona nuclear reactor.
In world politics, the most significant risks of nuclear war are not those of madness or irrationality. They are the cumulatively catastrophic risks of sane and rational decisions. For Israel, this means the worst-case Iranian nuclear war scenario is not the popular narrative of mad leadership in Tehran, but one of sane adversaries operating in opposition to sane adversaries in Jerusalem.
In this bewildering world order, the accumulated risks of a mutually sane search for escalation dominance could include nuclear war. Israeli leaders should be wary of mad or prospectively mad Iranian leaders, but even more wary of the nuclear consequences posed by sane and rational Iranian decision-makers.
Prof. Louis René Beres was educated at Princeton (Ph.D., 1971) and is the author of many books and scholarly articles dealing with international law, nuclear strategy, nuclear war, and terrorism. In Israel, Prof. Beres was Chair of Project Daniel (PM Sharon). His 12th and latest book is Surviving Amid Chaos: Israel’s Nuclear Strategy (Rowman & Littlefield, 2016; 2nd ed., 2018). A version of this article was originally published by The BESA Center.
The post Nuclear War in the Middle East first appeared on Algemeiner.com.
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As Gaza War Continues, Hamas Calls for Global Protests While Israel Marks Breakthroughs in Medical Innovation

A pro-Hamas march in London, United Kingdom, Feb. 17, 2024. Photo: Chrissa Giannakoudi via Reuters Connect
As the Palestinian terrorist group Hamas calls for global protests amid stalled Gaza ceasefire talks, Israel has broken new ground despite the ongoing conflict, achieving a major medical breakthrough in synthetic human kidney development.
The contrast illustrates a stark contrast between the priorities of Hamas, an international designated terrorist group that has ruled Gaza for nearly two decades, and Israel, the lone democracy in the Middle East that has long been a leader in tech and medical innovation.
On Wednesday, Hamas urged worldwide protests in support of Palestinians, calling on the international community “to denounce Israel’s genocidal war and starvation policy in Gaza.”
“We call for continuing and escalating the popular pressure in all cities and squares on Friday, Saturday, and Sunday … through rallies, demonstrations and sit-ins outside the embassies of the Israeli regime and its allies, particularly in the US,” the statement read.
The Palestinian terrorist group also called to expose what it described as “the terrorism of the Zio-Nazi occupation against defenseless civilians.”
Hamas’s latest move against Israel comes amid stalled indirect negotiations over a proposed 60-day ceasefire and hostage release deal, which collapsed last month after the group vowed it would not disarm unless an independent Palestinian state is established — rejecting a key Israeli demand to end the war in Gaza.
In its statement, Hamas demanded the opening of all border crossings to allow immediate aid into the war-torn enclave and urged a global condemnation of “the international community’s inaction on the Israeli crimes.”
Amid mounting international pressure to address the humanitarian crisis in Gaza, Israel announced new measures to facilitate the delivery of aid, including temporary pauses in fighting in certain areas and the creation of protected routes for aid convoys.
Israeli officials have previously accused Hamas of diverting aid for terrorist activities and selling supplies at inflated prices to civilians, while also blaming the United Nations and other foreign organizations for enabling this diversion.
Hamas’s statement also emphasized that the “global resistance movement must continue until Israeli aggression on Gaza ends and the siege on the coastal strip is lifted.”
Meanwhile, as Israel faces escalating hostilities and the heavy toll of war, the Jewish state continues to push the boundaries of innovation and resilience, achieving new medical breakthroughs while confronting ongoing challenges.
In a major medical breakthrough, scientists at Sheba Medical Center and Tel Aviv University have successfully grown a synthetic 3D miniature human kidney in a lab using specialized stem cells derived from kidney tissue — one of the most promising advances in regenerative medicine.
Dr. Dror Harats, chairman of Sheba’s Research Authority, described this achievement as a reflection of Israel’s leading role in global medical innovation.
“Despite growing efforts to isolate Israel from international science, breakthroughs like this prove our impact is both lasting and essential,” he said.
In a landmark study, a team from Sheba’s Safra Children’s Hospital and Tel Aviv University’s Sagol Center for Regenerative Medicine created synthetic kidney organs that matured and remained stable for 34 weeks — the longest-lasting and most refined kidney organoids developed to date.
Nearly a decade ago, the research team became the first to successfully isolate human kidney tissue stem cells — the cells responsible for the organ’s development and growth.
Previous attempts to grow kidneys in a lab using general-purpose stem cells were short-lived, typically lasting only a few weeks and often producing unwanted cell types that compromised research accuracy.
However, this Israeli research team used stem cells taken directly from kidney tissue — cells that naturally develop into kidney parts — allowing them to create a much purer and more stable model with key features found in real kidneys.
This medical breakthrough could have far-reaching implications, redefining the current understanding of kidney diseases and advancing the development of innovative treatments.
Researchers believe the model could help assess how medications impact fetal kidneys during pregnancy and move science closer to repairing or replacing damaged kidney tissue with lab-grown cells.
The discovery came days after researchers from Hebrew University of Jerusalem and international partners discovered a way to boost the immune system’s cancer-fighting ability by reprogramming how T cells, which are white blood cells critical to the immune system, produce energy.
The researchers explained in a study published in the peer-reviewed Nature Communications that disabling a protein known as Ant2 in T cells greatly enhances their effectiveness against tumors.
“By disabling Ant2, we triggered a complete shift in how T cells produce and use energy,” Prof. Michael Berger of Hebrew University’s Faculty of Medicine, who co-led the study with doctorate student Omri Yosef, told the Tazpit Press Service. “This reprogramming made them significantly better at recognizing and killing cancer cells.”
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Netherlands to Push EU to Suspend Israel Trade Deal but Won’t Recognize Palestinian State ‘At This Time’

Netherlands Foreign Affairs Minister Caspar Veldkamp addresses a press conference, in New Delhi on April 1, 2025. Photo: ANI Photo/Sanjay Sharma via Reuters Connect
The Netherlands is spearheading efforts to suspend the European Union-Israel trade agreement amid rising EU criticism of Israel’s actions in Gaza, while simultaneously refusing to recognize a Palestinian state, contrasting with other member states as international pressure mounts.
On Thursday, Dutch Foreign Minister Caspar Veldkamp announced that the Netherlands will push the EU to suspend the trade component of the EU-Israel Association Agreement — a pact governing the EU’s political and economic ties with the Jewish state.
This latest anti-Israel initiative follows a recent EU-commissioned report accusing Israel of committing “indiscriminate attacks … starvation … torture … [and] apartheid” against Palestinians in Gaza during its military campaign against Hamas, an internationally designated terrorist group.
Following calls from a majority of EU member states for a formal investigation, this report built on Belgium’s recent decision to review Israel’s compliance with the trade agreement, a process initiated by the Netherlands and led by EU High Representative for Foreign Affairs and Security Policy Kaja Kallas.
According to the report, “there are indications that Israel would be in breach of its human rights obligations” under the 25-year-old EU-Israel Association Agreement.
While the document acknowledges the reality of violence by Hamas, it states that this issue lies outside its scope — failing to address the Palestinian terrorist group’s role in sparking the current war with its bloody rampage across southern Israel on Oct. 7, 2023.
Israeli officials have slammed the report as factually incorrect and morally flawed, noting that Hamas embeds its military infrastructure within civilian targets and Israel’s army takes extensive precautions to try and avoid civilian casualties.
In a Dutch parliamentary debate on Gaza on Thursday, Veldkamp also announced that the government would not recognize a Palestinian state for now — a position that stands in sharp contrast to the recent moves by several other EU member states to extend recognition.
“The Netherlands is not planning to recognize a Palestinian state at this time,” the Dutch diplomat said.
“This war has ceased to be a just war and is now leading to the erosion of Israel’s own security and identity,” he continued.
This latest decision goes against the position of several EU member states, including France, which has committed to recognizing Palestinian statehood in September.
The United Kingdom has likewise indicated it will do so unless Israel acts to ease the humanitarian crisis in Gaza and agrees to a ceasefire.
For its part, Germany said it was not planning to recognize a Palestinian state in the short term, and Italy argued that recognition must occur simultaneously with the recognition of Israel by the new entity.
Spain, Norway, Ireland, and Slovenia all recognized a Palestinian state last year.
Israel has been facing growing pressure from several EU member states seeking to undermine its defensive campaign against the Palestinian terrorist group Hamas in Gaza.
On Thursday, European Commission Vice President Teresa Ribera strongly condemned Israel’s actions in the war-torn enclave, describing the situation as a “grave violation of human dignity.”
“What we are seeing is a concrete population being targeted, killed and condemned to starve to death,” Ribera told Politico. “If it is not genocide, it looks very much like the definition used to express its meaning.”
Until now, the European Commission has refrained from accusing Israel of genocide, but Ribera’s comments mark one of the strongest European condemnations since the outbreak of the war in Gaza.
She also called on the EU to take decisive action by considering the suspension of its trade agreement with Israel and the implementation of sanctions, while emphasizing that such measures would require unanimous approval from all member states.
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Graduate Student Unions Promoting Antisemitism, Reform Group Says

Students listen to a speech at a protest encampment at Stanford University in Stanford, California US, on April 26, 2024. Photo: Carlos Barria via Reuters Connect.
Higher-education-based unions controlled by United Electrical, Radio, and Machine Workers of America (UE) are rife with antisemitism and anti-Zionist discrimination, according to a new letter imploring the US Congress’s House Committee on Education and the Workforce to address the matter.
“Tracing its roots to communism in the 1930s, the UE is a radical, pro-Hamas labor union that has a long history of antisemitism,” the National Right to Work Foundation (NRTW), one of the US’s leading labor reform groups, wrote on July 30 in a message obtained by The Algemeiner. “The UE openly supports the boycott, divestment, and sanctions (BDS) movement, which is designed to cripple and destroy Israel economically. Today, the UE furthers its antisemitic agenda by unionizing graduate students on college campuses and using its exclusive representation powers to create a hostile environment for Jewish students. The hostile environment includes demanding compulsory dues to fund the UE’s abhorrent activities.”
NRTW went on to describe a litany of alleged injustices to which UE members subject Jewish student-employees in the US’s most prestigious institutions of higher education, from the Massachusetts Institute of Technology (MIT) to Cornell University. At MIT, the letter said, “union officers” aided a riotous group which illegally occupied a section of campus with a “Gaza Solidarity Encampment,” participating in the demonstration and even denying access to campus buildings. UE members at Stanford University, meanwhile, allegedly denied religious accommodations to Jewish students who requested exemption from union dues over that branch’s supporting the BDS movement. And Cornell University UE was accused of denying religious exemptions in several cases as well and followed up the rejection with an intrusive “questionnaire” which probed Jewish students for “legally-irrelevant information.”
The situation requires federal oversight and intervention, NRTW said, including Congress’s possibly clarifying that student-employees are not traditional employees and are therefore afforded protections under sections of the Civil Rights Act which apply to the campus.
“These continuing patterns of antisemitism are illegal, immoral, and must be stopped,” the letter continued. “We encourage you to do all that is in your power to investigate and help bring an end to the UE and its affiliates’ nonstop harassment and intimidation of Jewish students … The Trump administration can also use tools available to it under Title VI and Title VI of the Civil Rights Act against colleges who work with unions to create a hostile environment for Jewish students.”
July’s letter is not the first time NRTW has publicized alleged antisemitic abuse in unions representing higher education employees.
In 2024, it represented a group of six City University of New York (CUNY) professors, five of whom are Jewish, who sued to be “freed” from CUNY’s Professional Staff Congress (PSC-CUNY) over its passing a resolution during Israel’s May 2021 war with Hamas which declared solidarity with Palestinians and accused the Jewish state of ethnic cleansing, apartheid, and crimes against humanity. The group contested New York State’s “Taylor Law,” which it said chained the professors to the union’s “bargaining unit” and denied their right to freedom of speech and association by forcing them to be represented in negotiations by an organization they claim holds antisemitic views.
That same year, NRTW prevailed in a discrimination suit filed to exempt another cohort of Jewish MIT students from paying dues to the Graduate Student Union (GSU). The students had attempted to resist financially supporting GSU’s anti-Zionism, but the union bosses attempted to coerce their compliance, telling them that “no principles, teachings, or tenets of Judaism prohibit membership in or the payment of dues or fees” to the union.
“All Americans should have a right to protect their money from going to union bosses they don’t support, whether those objections are based on religion, politics, or any other reason,” NRTW said at the time.
Follow Dion J. Pierre @DionJPierre.