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Raphael Mechoulam, Israel’s ‘father of cannabis research,’ dies at 92

(JTA) — In the early 1960s, a Bulgarian-born scientist named Raphael Mechoulam was caught carrying five kilograms of, as he called it, “superb, smuggled Lebanese hashish” on a bus from Tel Aviv to Rehovot. But he wasn’t planning on smoking the stuff.

Mechoulam was a fledgling researcher keen on exploring the science behind cannabis, a stigmatized plant whose specific medical properties were not yet known. Over the decades he became a pioneer in cannabis research, whose findings about the psychoactive substance helped ease its entry out of the counterculture and into the mainstream. 

Mechoulam died in Israel at age 92; his death was announced Friday by American Friends of the Hebrew University, where Mechoulam helped form The Hebrew University Multidisciplinary Center for Cannabinoid Research in 2017.

“Most of the human and scientific knowledge about cannabis was accumulated thanks to Prof. Mechoulam,” Hebrew University President Asher Cohen said in a statement. “He paved the way for groundbreaking studies and initiated scientific cooperation between researchers around the world. Mechoulam was a sharp-minded and charismatic pioneer.”

As a professor in the Hebrew University School of Pharmacy, Mechoulam and his research team isolated THC, the psychoactive component of cannabis, as well as cannabidiol, or CBD, an active ingredient in cannabis with a range of medicinal benefits. 

He also pioneered the study of the body’s own cannabinoid system, which produces chemicals similar to THC to help regulate appetite, manage pain and operate the immune system.

As Mechoulam discovered more about cannabis and its efficacy in easing symptoms of cancer, epilepsy and other diseases, he lamented that strict drug laws in the United States and elsewhere suppressed research and kept the derivatives of cannabis off the market.

“Medicinal cannabis has to follow medical lines of thought and development and modern medical routes” in order to be part of proper drugs, he told the New York Times in 2017. “Israel has more [clinical trials] than the United States at the moment, which is ridiculous.”

Mechoulam was a founding member of the International Association for Cannabinoid Medicines and the International Cannabinoid Research Society. In 1994, he was elected to be a member of the Israel Academy of Sciences and Humanities.

Mechoulam was born in Bulgaria in 1930 and immigrated in 1949 with his family to Israel, where he later studied chemistry. He received his PhD at the Weizmann Institute in Rehovot, writing a thesis on the chemistry of steroids. After postdoctoral studies at the Rockefeller Institute in New York, he joined the scientific staff of the Weizmann Institute.

Mechoulam became a full professor at Hebrew University in 1972 and was named the Lionel Jacobson Professor of Medicinal Chemistry in 1975, serving as the university’s rector from 1979-1982. 

In 2022, the YIVO Institute for Jewish Research in New York City mounted its exhibition on Jewish contributions to the history of cannabis and highlighted the work of Mechoulam. He’s worked on cannabis his entire life, and in the 1990s he and his colleagues discovered the endocannabinoid system, which regulates homeostasis — a significant discovery on how the human body deals with cannabinoids,” Eddy Portnoy, who curated the exhibit, told the Jewish Telegraphic Agency at the time. “I read an interview with him where he says that because he was in a small country, he would have to find a niche that other people weren’t working in.”


The post Raphael Mechoulam, Israel’s ‘father of cannabis research,’ dies at 92 appeared first on Jewish Telegraphic Agency.

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US Military: ‘Locked and Loaded’ to Strike Iran’s Power Plants, Energy Industry if Ordered

US Secretary of Defense Pete Hegseth speaks during a briefing on the Iran war, at the Pentagon in Washington, DC, US, April 16, 2026. Photo: REUTERS/Nathan Howard

The US naval blockade of Iran is just an example of “polite” behavior during the ongoing ceasefire and US forces are ready to strike Iran’s power plants and energy industry if ordered, US Defense Secretary Pete Hegseth said on Thursday.

Standing alongside two of the US military‘s most senior officers, Hegseth said Iran needs to choose wisely as it prepares for negotiations with the United States.

“We are reloading with more power than ever before, and better intelligence,” Hegseth said at a Pentagon news briefing. “We are locked and loaded on your critical dual-use infrastructure, on your remaining power generation, and on your energy industry. We’d rather not have to do it.”

President Donald Trump’s administration expressed optimism on Wednesday about reaching a deal to end the Iran war, while also warning of increasing economic pressure against Iran if it remains defiant.

That has included a blockade of Iran that went into effect on ‌Monday, with the US military forcing 14 ships to turn around. Dozens of US warships and aircraft, including about 10,000 military personnel, are enforcing the blockade.

Trump is hoping the effort will force Iran to accept US terms ⁠for ending the war, which was launched by the US and Israel on Feb. 28, including opening up the Strait of Hormuz, a waterway through which roughly one fifth of global oil and gas exports ordinarily transits. Trump has said ​that was also a condition of the ceasefire due to expire next week.

The war has resulted in a major disruption of global oil and gas supplies.

Analysts have said that Iran can withstand a complete halt ​in oil exports of up to two months before being forced to curb production.

Hegseth, in comments aimed at the Iranian leadership, said that the blockade “is the polite way that this can go.”

READY TO RESUME OPERATIONS

Admiral Brad Cooper, the head of US Central Command, which oversees military operations in the Middle East, said the military was adjusting tactics, techniques, and procedures, but he did not provide any details.

During the same briefing, General Dan ​Caine, chairman of the US military‘s Joint Chiefs of Staff, added that American forces are “ready to resume major combat operations at literally a moment’s notice.”

US Navy ships would pursue any Iranian-flagged vessel or any vessel attempting to provide material support to Iran, ​Caine told the briefing. He added that could take place not just in the region, but also the Indo-Pacific.

Ships trying to break the blockade would be intercepted and warned that “if you do not comply with this blockade, we will use force,” and enforcement would occur inside Iran’s territorial seas and in international waters, Caine said.

No ships have been boarded so far, Caine said.

The US military has widened its blockade to include cargoes deemed contraband, and any vessels suspected of trying to reach Iranian territory will be “subject to belligerent right to visit and search,” the US Navy said in an advisory on Thursday.

“These vessels, regardless of location, are subject to visit, board, search, and seizure,” the Navy said in an updated advisory.

Contraband items listed included weapons, weapons systems, ammunition, nuclear materials, crude, and refined oil products as well as iron, steel and aluminum.

Sources briefed by Tehran have told Reuters that Iran could let ships sail freely through the Omani side ​of the Strait of Hormuz without risk of attack under proposals it has offered in talks with the US, providing a deal is ‌clinched to prevent renewed conflict.

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Trump Says Lebanon and Israel Have Reached 10-Day Ceasefire

Smoke rises following an airstrike in Lebanon, as seen from Israeli side of the border, April 11, 2026. Photo: REUTERS/Amir Cohen

US President Donald Trump said on Thursday that Israel and Lebanon had agreed to begin a 10-day ceasefire at 5 pm EST (2100 GMT), signaling a pause in Israel‘s conflict with Iran-backed terrorist group Hezbollah that has raged in parallel to the war with Iran.

A US official said the ceasefire would start on Thursday.

After announcing the deal on social media, Trump told reporters that leaders of the two countries could meet at the White House over the next week or two.

“It’s very exciting. I think we’re going to have a deal where we’re going to have a meeting, first time in 44 years, and Lebanon will be meeting with Israel, and they’re probably going to do it at the White House over the next week or two,” Trump said, adding that he spoke with both leaders as the ceasefire was announced and was working on a longer term deal.

Pakistan’s Foreign Ministry had earlier said that peace in Lebanon was essential for talks it is mediating to end the war between the United States and Iran.

Trump said he had held excellent conversations with both Lebanese President Joseph Aoun and Israeli Prime Minister Benjamin Netanyahu.

An Israeli cabinet source said Netanyahu’s security cabinet had convened for an urgent discussion on the Lebanon ceasefire.

An Israeli security official, speaking on the condition of anonymity, said the Israeli military had no plans to withdraw forces from southern Lebanon during a ceasefire.

In its first comment after Trump‘s announcement, Hezbollah said any ceasefire must not allow Israel freedom of movement within Lebanon. In a statement issued by its media office, the terrorist group said the presence of Israeli troops on Lebanese territory granted Lebanon and its people the “right to resist.”

‘BUFFER ZONE’

Lebanon was dragged into the war in the Middle East on March 2, when Hezbollah opened fire in support of Tehran, prompting an Israeli offensive in Lebanon just 15 months after the last major conflict between the Shi’ite Islamist group and Israel.

Israeli attacks have killed more than 2,100 people in Lebanon since March 2 and forced more than 1.2 million to flee, Lebanese authorities say. Most of those killed have been Hezbollah terrorists, according to Israeli tallies. Hezbollah attacks have killed two ⁠Israeli civilians, while 13 Israeli soldiers have died in Lebanon since March 2, Israel says.

Israeli forces have entered areas of southern Lebanon and vowed to maintain control over territory extending all the way to the Litani River, which meets the Mediterranean some 30 km (20 miles) north of Israel‘s border. Israel ordered residents out of the area south of the Litani during the war.

Israeli troops have since destroyed Lebanese villages in the area, saying their aim is to create a “buffer zone” to protect northern Israeli towns from Hezbollah attacks.

Senior Hezbollah lawmaker Hassan Fadlallah, speaking to Reuters minutes before Trump‘s announcement, said the group had been informed by Iran’s ambassador to Lebanon that a ceasefire could begin on Thursday evening. After the announcement, he said it would be for 10 days.

Asked if Hezbollah would commit to the truce, Fadlallah said everything depended on Israel halting all forms of hostilities, and credited Iran’s diplomatic efforts for the possible ceasefire.

BEIRUT AT ODDS WITH HEZBOLLAH

The Lebanese government has been sharply at odds with Hezbollah over its decision to enter the war, having spent the last year seeking to secure the peaceful disarmament of the group founded by Iran’s Revolutionary Guards in 1982.

Israeli and Lebanese ambassadors held rare talks in Washington on Tuesday, despite objections from Hezbollah.

Trump said he had directed US Vice President JD Vance, Secretary of State Marco Rubio, and Chairman of the Joint Chiefs of Staff Dan Caine to work with the two countries to achieve lasting peace. “Both sides want to see PEACE, and I believe that will happen, quickly!” he said in a post on Truth Social.

In another social media post, Trump said he would be inviting Netanyahu and Aoun to the White House for “meaningful talks” between the two countries, which have remained in an official state of war since Israel was established in 1948.

Trump had earlier said that Lebanese and Israeli leaders would speak on Thursday for the first time in decades. However, Lebanese officials said Aoun did not speak with Netanyahu on Thursday, and that Lebanon‘s US embassy had informed Washington he would not speak to him in the near future.

BATTLE FOR BORDER TOWN

Speaking to Reuters again after Trump‘s announcement, Hezbollah lawmaker Fadlallah said Lebanese displaced from the south should wait for the ceasefire to take hold and be extremely cautious in villages occupied by Israeli troops.

Fighting continued to rage in south Lebanon on Thursday, notably in the border town of Bint Jbeil, a Hezbollah stronghold and strategic prize. A senior Lebanese official said Lebanon believed Israel wanted to secure a victory in Bint Jbeil before diplomatic progress could be made.

An Israeli strike destroyed the last bridge over the Litani River into the south, a senior Lebanese security source said, fully severing the area from the rest of the country after Israel destroyed other crossings during the war.

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Three Arrested After Attempted Arson at Persian-Language Media Office in London

A Metropolitan Police Service (MPS) car. Photo: Wikimedia Commons.

British police said on Thursday they had arrested three people in ‌connection with an attempted arson attack on the offices of a Persian-language media organization in northwest London, which followed two similar incidents in the British capital.

An ignited container was thrown toward the premises of the parent company of Iran International, Volant Media, on Wednesday evening, ​landing in a car park where the fire extinguished itself. No damage was reported and there were no ​injuries, the police said.

Two men, aged 19 and 21, and a 16-year-old boy were arrested ⁠on suspicion of arson endangering life. The arson attempt was not being treated as terrorism, but counterterrorism officers were ​involved in the investigation, police said.

Iran International said a suspicious vehicle was denied entry to its London site shortly before ​incendiary devices were thrown into a nearby car park.

It said it viewed the incident in the context of “growing threats and intimidation” directed at the organization and its journalists.

The incident comes a day after police arrested two suspects following an attempted arson attack on a synagogue, ​also in north London.

JEWISH COMMUNITIES AND IRANIAN DIASPORA INCREASINGLY TARGETED, POLICE SAY

Last month, several ambulances belonging to the Jewish volunteer ​emergency service Hatzola were set alight while parked near a synagogue in the Golders Green area of north London.

Matt Jukes, a deputy ‌commissioner ⁠for London’s Metropolitan Police, said in a statement on Thursday he understood why conflict overseas and heightened tensions in Britain would be “deeply worrying.”

“London’s Jewish communities and the Iranian diaspora in London have, in recent years, been increasingly targeted by individuals, groups, and hostile states intent on spreading fear, hate, and harm,” Jukes said.

British authorities have previously warned that there is ​a threat to journalists working ​for Persian-language outlets that ⁠are critical of Iran’s government. In 2024, a journalist working for the television news network Iran International was stabbed in the leg near his home in south London.

Britain’s MI5 spy boss ​said last October that his agency and British police had tracked more than 20 ​Iranian-backed plots to ⁠kidnap or kill British nationals or individuals based in Britain who were regarded by Tehran as a threat.

“We are dealing with an unprecedented level of national security investigations, some with suspected links to foreign states and many of those have dangerous and ⁠often reckless ​intentions,” Vicki Evans, senior national coordinator for Counter Terrorism Policing, told ​reporters on Thursday.

She added that the incidents had taken place against a backdrop of “global instability within which we’re seeing sustained and increasing aggressive and hostile ​activity.”

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