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Raphael Mechoulam, Israel’s ‘father of cannabis research,’ dies at 92
(JTA) — In the early 1960s, a Bulgarian-born scientist named Raphael Mechoulam was caught carrying five kilograms of, as he called it, “superb, smuggled Lebanese hashish” on a bus from Tel Aviv to Rehovot. But he wasn’t planning on smoking the stuff.
Mechoulam was a fledgling researcher keen on exploring the science behind cannabis, a stigmatized plant whose specific medical properties were not yet known. Over the decades he became a pioneer in cannabis research, whose findings about the psychoactive substance helped ease its entry out of the counterculture and into the mainstream.
Mechoulam died in Israel at age 92; his death was announced Friday by American Friends of the Hebrew University, where Mechoulam helped form The Hebrew University Multidisciplinary Center for Cannabinoid Research in 2017.
“Most of the human and scientific knowledge about cannabis was accumulated thanks to Prof. Mechoulam,” Hebrew University President Asher Cohen said in a statement. “He paved the way for groundbreaking studies and initiated scientific cooperation between researchers around the world. Mechoulam was a sharp-minded and charismatic pioneer.”
As a professor in the Hebrew University School of Pharmacy, Mechoulam and his research team isolated THC, the psychoactive component of cannabis, as well as cannabidiol, or CBD, an active ingredient in cannabis with a range of medicinal benefits.
He also pioneered the study of the body’s own cannabinoid system, which produces chemicals similar to THC to help regulate appetite, manage pain and operate the immune system.
As Mechoulam discovered more about cannabis and its efficacy in easing symptoms of cancer, epilepsy and other diseases, he lamented that strict drug laws in the United States and elsewhere suppressed research and kept the derivatives of cannabis off the market.
“Medicinal cannabis has to follow medical lines of thought and development and modern medical routes” in order to be part of proper drugs, he told the New York Times in 2017. “Israel has more [clinical trials] than the United States at the moment, which is ridiculous.”
Mechoulam was a founding member of the International Association for Cannabinoid Medicines and the International Cannabinoid Research Society. In 1994, he was elected to be a member of the Israel Academy of Sciences and Humanities.
Mechoulam was born in Bulgaria in 1930 and immigrated in 1949 with his family to Israel, where he later studied chemistry. He received his PhD at the Weizmann Institute in Rehovot, writing a thesis on the chemistry of steroids. After postdoctoral studies at the Rockefeller Institute in New York, he joined the scientific staff of the Weizmann Institute.
Mechoulam became a full professor at Hebrew University in 1972 and was named the Lionel Jacobson Professor of Medicinal Chemistry in 1975, serving as the university’s rector from 1979-1982.
In 2022, the YIVO Institute for Jewish Research in New York City mounted its exhibition on Jewish contributions to the history of cannabis and highlighted the work of Mechoulam. “He’s worked on cannabis his entire life, and in the 1990s he and his colleagues discovered the endocannabinoid system, which regulates homeostasis — a significant discovery on how the human body deals with cannabinoids,” Eddy Portnoy, who curated the exhibit, told the Jewish Telegraphic Agency at the time. “I read an interview with him where he says that because he was in a small country, he would have to find a niche that other people weren’t working in.”
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Trump Says Gas Prices May Remain High Through November Midterm Election
U.S. President Donald Trump takes questions from reporters while Vice President JD Vance and Secretary of State Marco Rubio look on, as they attend a meeting with oil industry executives, at the White House in Washington, D.C., U.S., January 9, 2026. REUTERS/Kevin Lamarque
US President Donald Trump said on Sunday that the price of oil and gasoline may remain high through November’s midterm elections, a rare acknowledgement of the potential political fallout from his decision to attack Iran six weeks ago.
“It could be, or the same, or maybe a little bit higher, but it should be around the same,” Trump, who is in Miami for the weekend, told Fox News’ “Sunday Morning Futures With Maria Bartiromo” when asked whether the cost of oil and gas would be lower by the fall.
The average price for regular gas at US service stations has exceeded $4 per gallon for most of April, according to data from GasBuddy. Trump’s comments on Sunday came after weeks of asserting that the spike in prices is a short-term phenomenon, though his top advisers are cognizant of the war’s economic impacts, officials have said.
Earlier on Sunday, Trump announced on social media that the US Navy would blockade the Strait of Hormuz and intercept any ship that paid a crossing fee to Iran, after marathon talks between the US and Iran in Pakistan over the weekend did not yield a peace deal.
“No one who pays an illegal toll will have safe passage on the high seas,” he wrote on Truth Social.
Any US blockade is likely to add more uncertainty to the eventual resolution of the conflict, which is currently subject to a tenuous two-week ceasefire. The new tactic is in response to Iran’s own closure of the strait’s critical shipping lanes, which has caused global oil prices to skyrocket about 50%.
UNPOPULAR WAR HITS TRUMP’S APPROVAL
The war began on February 28, when the US launched a joint bombing campaign with Israel against Iran. The scope quickly expanded as Iran and its allies attacked nearby countries, while Israel targeted Hezbollah with massive strikes in Lebanon.
The war has buffeted global financial markets and caused thousands of civilian deaths, mostly in Iran and Lebanon.
Trump’s political standing at home has suffered, with polls showing the war is unpopular among most Americans, who are frustrated by rising gasoline prices.
The president’s approval rating has hit the lowest levels of his second term in office, raising concern among Republicans that his party is poised to lose control of Congress in the midterm elections. A Democratic majority in either chamber could launch investigations into the Trump administration while blocking much of his legislative agenda.
US Senator Mark Warner of Virginia, the ranking Democrat on the Senate Intelligence Committee, questioned the strategy behind Trump’s planned blockade.
“I don’t understand how blockading the strait is going to somehow push the Iranians into opening it,” he told CNN’s “State of the Union” on Sunday.
In a separate appearance on CBS’s “Face the Nation,” Warner said the blockade would not undermine Iranian control of the waterway.
“The Iranians have hundreds of speedboats where they can still mine the strait or put bombs against tankers in closing the strait,” he said. “How is that going to ever bring down gas prices?”
Although Trump has repeatedly said that the war would be over soon, Republican US Senator Ron Johnson of Wisconsin told ABC News’ “This Week” on Sunday that achieving US aims in Iran “could take a long time.”
“It’s going to be a long-term project,” said Johnson, who was not asked about Trump’s proposed blockade. “I never thought this would be easy.”
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Israel’s Ben-Gvir Visits Flashpoint Al-Aqsa Mosque Compound
Israeli politician Itamar Ben-Gvir walks inside the Knesset, in Jerusalem, Oct. 13, 2025. Photo: Chip Somodevilla/Pool via REUTERS
Israel’s far-right police minister Itamar Ben-Gvir visited the flashpoint Al-Aqsa Mosque compound in Jerusalem on Sunday, saying he was seeking greater access for Jewish worshipers and drawing condemnation from Jordan and the Palestinians.
The compound in Jerusalem’s walled Old City is one of the most sensitive sites in the Middle East. Known to Jews as Temple Mount, it is the most sacred site in Judaism and is Islam’s third-holiest site.
Under a delicate, decades-old arrangement with Muslim authorities, it is administered by a Jordanian religious foundation and Jews can visit but may not pray there.
Suggestions that Israel would alter the rules have sparked outrage among Muslims and ignited violence in the past.
“Today, I feel like the owner here,” National Security Minister Ben-Gvir said in a video filmed at the site and distributed by his office. “There is still more to do, more to improve. I keep pushing the Prime Minister (Benjamin Netanyahu) to do more and more — we must keep rising higher and higher.”
A statement from the Jordanian foreign ministry said it considered Ben-Gvir’s visit to be a violation of the status quo agreement at the site and “a desecration of its sanctity, a condemnable escalation and an unacceptable provocation.”
The office of Palestinian president, Mahmoud Abbas, said such actions could further destabilize the region.
Ben-Gvir’s spokesman said the minister was seeking greater access and prayer permits for Jewish visitors. He also said that Ben-Gvir had prayed at the site.
There was no immediate comment from Netanyahu’s office. Previous such visits and statements by Ben-Gvir have prompted Netanyahu announcements saying that there is no change in Israel’s policy of keeping the status quo.
Muslim, Christian and Jewish sites, including Al-Aqsa had been largely closed to the public during the Iran war. There was no immediate sign of unrest on Sunday after Ben-Gvir’s visit.
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Netanyahu Visits Troops Fighting Hezbollah in Southern Lebanon
Israeli Prime Minister Benjamin Netanyahu speaks during a press conference at the Prime Minister’s office in Jerusalem, Aug. 10, 2025. Photo: ABIR SULTAN/Pool via REUTERS
i24 News – Israeli Prime Minister Benjamin Netanyahu visited Israeli forces operating in southern Lebanon on Sunday as military operations against Hezbollah-linked targets continue.
Netanyahu toured forward positions alongside Defense Minister Yisrael Katz, Eyal Zamir, and Northern Command Commander Rafi Milo, meeting troops and receiving operational briefings from commanders on the ground.
Speaking to soldiers, Netanyahu praised their performance and said operations in the Lebanese security zone were ongoing.
“The war continues, including within the security zone in Lebanon,” he said, adding that Israeli forces were working to prevent infiltration attempts and neutralize threats such as anti-tank fire and missiles.
He described the northern campaign as part of a broader regional struggle involving Iran and its allies, saying Israel’s adversaries were now “fighting for their survival” following sustained Israeli military pressure.