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Raphael Mechoulam, Israel’s ‘father of cannabis research,’ dies at 92
(JTA) — In the early 1960s, a Bulgarian-born scientist named Raphael Mechoulam was caught carrying five kilograms of, as he called it, “superb, smuggled Lebanese hashish” on a bus from Tel Aviv to Rehovot. But he wasn’t planning on smoking the stuff.
Mechoulam was a fledgling researcher keen on exploring the science behind cannabis, a stigmatized plant whose specific medical properties were not yet known. Over the decades he became a pioneer in cannabis research, whose findings about the psychoactive substance helped ease its entry out of the counterculture and into the mainstream.
Mechoulam died in Israel at age 92; his death was announced Friday by American Friends of the Hebrew University, where Mechoulam helped form The Hebrew University Multidisciplinary Center for Cannabinoid Research in 2017.
“Most of the human and scientific knowledge about cannabis was accumulated thanks to Prof. Mechoulam,” Hebrew University President Asher Cohen said in a statement. “He paved the way for groundbreaking studies and initiated scientific cooperation between researchers around the world. Mechoulam was a sharp-minded and charismatic pioneer.”
As a professor in the Hebrew University School of Pharmacy, Mechoulam and his research team isolated THC, the psychoactive component of cannabis, as well as cannabidiol, or CBD, an active ingredient in cannabis with a range of medicinal benefits.
He also pioneered the study of the body’s own cannabinoid system, which produces chemicals similar to THC to help regulate appetite, manage pain and operate the immune system.
As Mechoulam discovered more about cannabis and its efficacy in easing symptoms of cancer, epilepsy and other diseases, he lamented that strict drug laws in the United States and elsewhere suppressed research and kept the derivatives of cannabis off the market.
“Medicinal cannabis has to follow medical lines of thought and development and modern medical routes” in order to be part of proper drugs, he told the New York Times in 2017. “Israel has more [clinical trials] than the United States at the moment, which is ridiculous.”
Mechoulam was a founding member of the International Association for Cannabinoid Medicines and the International Cannabinoid Research Society. In 1994, he was elected to be a member of the Israel Academy of Sciences and Humanities.
Mechoulam was born in Bulgaria in 1930 and immigrated in 1949 with his family to Israel, where he later studied chemistry. He received his PhD at the Weizmann Institute in Rehovot, writing a thesis on the chemistry of steroids. After postdoctoral studies at the Rockefeller Institute in New York, he joined the scientific staff of the Weizmann Institute.
Mechoulam became a full professor at Hebrew University in 1972 and was named the Lionel Jacobson Professor of Medicinal Chemistry in 1975, serving as the university’s rector from 1979-1982.
In 2022, the YIVO Institute for Jewish Research in New York City mounted its exhibition on Jewish contributions to the history of cannabis and highlighted the work of Mechoulam. “He’s worked on cannabis his entire life, and in the 1990s he and his colleagues discovered the endocannabinoid system, which regulates homeostasis — a significant discovery on how the human body deals with cannabinoids,” Eddy Portnoy, who curated the exhibit, told the Jewish Telegraphic Agency at the time. “I read an interview with him where he says that because he was in a small country, he would have to find a niche that other people weren’t working in.”
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Israel Publishes Draft Law Seeking to Boost State Revenues From Dead Sea Minerals
A drone picture shows part of the Dead Sea and its shore near Ein Gedi, Israel, Feb. 7, 2025. Photo: REUTERS/Ilan Rosenberg
Israel on Wednesday published a draft law that aims to boost state revenues from a concession for extracting minerals from the Dead Sea as well as tackling its environmental consequences.
The Finance Ministry said the proposed law intends to redefine the concession to ensure the public and the state get their rightful share, while ensuring the preservation of nature and environmental values.
“The law serves as the basis for allocating the concession and the terms of the future tender for resource extraction from the Dead Sea, with an emphasis on promoting optimal competition, lowering entry barriers, and attracting leading international players,” it said.
Fertilizer maker ICL Group has held the concession, giving it exclusive rights to minerals from the Dead Sea site, for five decades, but its permit is set to expire in 2030.
Last month, ICL gave up right of first refusal for its Dead Sea concession under a government plan to open it up for tender, although it would receive some $3 billion if it loses the permit when it expires.
ICL, one of the world’s largest potash producers, has previously said its Dead Sea assets were worth $6 billion. ICL extracts mainly potash and magnesium from the concession.
Under the draft law, which still needs preliminary approval from lawmakers, the state‘s share of concession profits would ultimately rise to an average of 50% from 35% currently, partly through royalties, the ministry said.
The law also aims to tackle negative impacts of resource extraction activities in the Dead Sea, which continues to shrink.
ICL plans to participate in the future tender and has said it believes it is the most suitable candidate to operate the future concession.
Accountant General Yali Rothenberg said the law places emphasis on fair, efficient, and responsible use of one of Israel’s most important natural resources.
It “will ensure that the state maximizes economic value for the public, promotes optimal competition, and protects the unique environment of the Dead Sea region for future generations,” he said.
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Israel Says It Received Body From Hamas, Indicates Rafah Crossing to Open Soon to Let Gazans Cross Into Egypt
People hold images of dead hostages Ran Gvili and Sudthisak Rinthalak, whose bodies haven’t been returned yet, as Israelis attend a rally calling for the immediate return of the remains of all hostages held in Gaza, more than two years after the deadly Oct. 7, 2023, attack on Israel by Hamas, at the Hostages Square in Tel Aviv, Israel, Nov. 29, 2025. Photo: REUTERS/Nir Elias
Israel received a body that the Palestinian terrorist group Hamas said was one of the last two deceased hostages in the Gaza Strip on Wednesday, as Israel said it would allow Gaza’s gateway to Egypt to open once all hostages were returned.
A body has been transferred by the Red Cross to the Israeli military and will undergo forensic identification, a statement from the Israeli Prime Minister’s Office said.
Hamas also handed over remains on Tuesday, which Prime Minister Benjamin Netanyahu’s office later said were not of any hostage.
The handover of the last hostages’ bodies in Gaza would complete a key condition of the initial part of US President Donald Trump’s plan to end the two-year Gaza war, which also provides for the Rafah border crossing between Gaza and Egypt to open in both directions.
Israel has kept the crossing shut since the ceasefire came into effect in October, saying that Hamas must abide by the agreement to return all hostages still in Gaza, living and deceased.
“The crossing will be opened both ways when all of our hostages have been returned,” Israeli government spokesperson Shosh Bedrosian told reporters.
Since the fragile truce started, Hamas has returned all 20 living hostages and 26 bodies in exchange for around 2,000 Palestinian detainees and convicted prisoners, but two more deceased captives – an Israeli police officer and a Thai agricultural worker – are still in Gaza.
ISRAEL SAYS PREVIOUS ‘FINDINGS’ NOT LINKED TO HOSTAGES
The armed wing of the Hamas-allied Palestinian Islamic Jihad terrorist group, the Al Quds Brigades, said it had found a hostage body after conducting a search in northern Gaza, along with a team from the Red Cross.
Hamas and Islamic Jihad said they had handed over the body to the Red Cross late on Wednesday afternoon. The groups did not say which of the two remaining deceased hostages they believed it to be.
The two are Israeli police officer Ran Gvili and Thai national Sudthisak Rinthalak, both kidnapped during Hamas’s Oct. 7, 2023, attack on Israel that triggered two years of devastating war in Gaza.
OPENING OF CROSSING COULD ALLOW OUT THOSE NEEDING TREATMENT
COGAT, the Israeli military arm that oversees humanitarian matters, said the Rafah crossing would be opened in the coming days to allow Palestinians to cross into Egypt.
The decision to open the crossing for those seeking to leave Gaza was made in “full coordination” with those that have mediated between Israel and Hamas during the war, Bedrosian said.
Egypt, along with Qatar and the US, has acted as a mediator.
COGAT said it would be opened under the supervision of a European Union mission – a similar mechanism to that employed during a previous Gaza ceasefire agreed in January 2025.
Before the war, the Rafah crossing was a key entry point for aid into the territory, as well as weapons smuggling for Hamas. It has been mostly closed throughout the conflict.
At least 16,500 patients in Gaza require medical care outside of the enclave, according to the United Nations. Some Gazans have managed to leave for medical treatment abroad through Israel.
Violence has tailed off since the Oct. 10 ceasefire but Israel has continued to strike Gaza and conduct demolitions against what it says is Hamas infrastructure. Hamas and Israel have traded blame for violating the US-backed agreement.
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Israel, Lebanon Send Civilian Envoys to Truce Committee for First Direct Talks in Decades
An Israeli citizen looks out from a viewpoint towards Lebanon, near the Israel-Lebanon border, as seen from northern Israel, Nov. 24, 2025. Photo: REUTERS/Shir Torem
Israel and Lebanon sent civilian envoys to a military committee monitoring their ceasefire, top officials from both said on Wednesday, in a move set to expand the scope of talks between the long-time foes for the first time.
The meeting was a step toward a months-old US demand that the two countries broaden talks beyond monitoring the 2024 ceasefire, in line with US President Donald Trump’s agenda of peace agreements across the Middle East.
It came even as fears of a renewed flare-up between Israel and powerful Lebanese terrorist group Hezbollah persist.
Lebanese Prime Minister Nawaf Salam told journalists he hoped civilian participation in the meetings would help “defuse tensions,” saying further Israeli strikes in recent weeks had been a clear escalatory signal.
Israeli Prime Minister Benjamin Netanyahu said the atmosphere at the meeting was good and that the sides agreed to put forth ideas for economic cooperation.
LEBANON OPEN TO US, FRENCH TROOPS
Lebanon and Israel have been officially enemy states for over 70 years, and Beirut criminalizes contacts with Israeli nationals. Meetings between civilian officials of each side have been extraordinarily rare throughout their fraught history.
Lebanese President Joseph Aoun has said in recent months, however, that he is open to negotiations to pursue a more robust truce and dispatched Lebanon‘s former ambassador to Washington, Simon Karam, to head his country’s delegation to the truce committee‘s meeting.
Netanyahu’s office said that it had sent the deputy head of foreign policy division at Israel‘s National Security Council to the meeting, as part of what it said was the ongoing dialogue between Israel, Lebanon, and the United States.
The committee, chaired by the United States, met on Wednesday for approximately three hours on the Blue Line, which serves as the frontier between Lebanon and Israel.
A statement issued after the session concluded said attendees welcomed the added envoys as an “important step” toward ensuring the committee is “anchored in lasting civilian as well as military dialogue.”
It said it looked forward to working with the representatives to nurture peace along the long-volatile border.
Israel and Lebanon agreed to a US-brokered ceasefire in 2024 that ended more than a year of fighting between Israel and Iran-backed Hezbollah. Since then, they have traded accusations over violations.
Salam said on Wednesday Lebanon was open to the committee taking on a direct verification role to check Israeli claims that Hezbollah is re-arming, and verify the work of the Lebanese army in dismantling the terrorist group’s infrastructure.
Asked by reporters if that meant Beirut was willing to have French and US troops on the ground, Salam said, “Of course.”
ISRAEL DEMANDS HEZBOLLAH DISARM
Netanyahu’s office said that regardless of any economic cooperation, Hezbollah must be disarmed.
Hezbollah’s media office did not immediately respond to questions from Reuters on the talks‘ expansion.
The Iranian-backed, Shi’ite Muslim group has repeatedly rejected any negotiations with Israel as a “trap.”
Despite the ceasefire, Israel has continued air strikes on what it says are Hezbollah’s efforts to rebuild its military capabilities in breach of the truce. Lebanon says Israel‘s bombardment and occupation of hilltop positions in south Lebanon amount to ceasefire breaches.
Fears have been growing in Lebanon that Israel will return to a full-blown military campaign after expressing frustration with the pace of Lebanese authorities’ efforts to seize Hezbollah weaponry across the country.