Uncategorized
Raphael Mechoulam, Israel’s ‘father of cannabis research,’ dies at 92
(JTA) — In the early 1960s, a Bulgarian-born scientist named Raphael Mechoulam was caught carrying five kilograms of, as he called it, “superb, smuggled Lebanese hashish” on a bus from Tel Aviv to Rehovot. But he wasn’t planning on smoking the stuff.
Mechoulam was a fledgling researcher keen on exploring the science behind cannabis, a stigmatized plant whose specific medical properties were not yet known. Over the decades he became a pioneer in cannabis research, whose findings about the psychoactive substance helped ease its entry out of the counterculture and into the mainstream.
Mechoulam died in Israel at age 92; his death was announced Friday by American Friends of the Hebrew University, where Mechoulam helped form The Hebrew University Multidisciplinary Center for Cannabinoid Research in 2017.
“Most of the human and scientific knowledge about cannabis was accumulated thanks to Prof. Mechoulam,” Hebrew University President Asher Cohen said in a statement. “He paved the way for groundbreaking studies and initiated scientific cooperation between researchers around the world. Mechoulam was a sharp-minded and charismatic pioneer.”
As a professor in the Hebrew University School of Pharmacy, Mechoulam and his research team isolated THC, the psychoactive component of cannabis, as well as cannabidiol, or CBD, an active ingredient in cannabis with a range of medicinal benefits.
He also pioneered the study of the body’s own cannabinoid system, which produces chemicals similar to THC to help regulate appetite, manage pain and operate the immune system.
As Mechoulam discovered more about cannabis and its efficacy in easing symptoms of cancer, epilepsy and other diseases, he lamented that strict drug laws in the United States and elsewhere suppressed research and kept the derivatives of cannabis off the market.
“Medicinal cannabis has to follow medical lines of thought and development and modern medical routes” in order to be part of proper drugs, he told the New York Times in 2017. “Israel has more [clinical trials] than the United States at the moment, which is ridiculous.”
Mechoulam was a founding member of the International Association for Cannabinoid Medicines and the International Cannabinoid Research Society. In 1994, he was elected to be a member of the Israel Academy of Sciences and Humanities.
Mechoulam was born in Bulgaria in 1930 and immigrated in 1949 with his family to Israel, where he later studied chemistry. He received his PhD at the Weizmann Institute in Rehovot, writing a thesis on the chemistry of steroids. After postdoctoral studies at the Rockefeller Institute in New York, he joined the scientific staff of the Weizmann Institute.
Mechoulam became a full professor at Hebrew University in 1972 and was named the Lionel Jacobson Professor of Medicinal Chemistry in 1975, serving as the university’s rector from 1979-1982.
In 2022, the YIVO Institute for Jewish Research in New York City mounted its exhibition on Jewish contributions to the history of cannabis and highlighted the work of Mechoulam. “He’s worked on cannabis his entire life, and in the 1990s he and his colleagues discovered the endocannabinoid system, which regulates homeostasis — a significant discovery on how the human body deals with cannabinoids,” Eddy Portnoy, who curated the exhibit, told the Jewish Telegraphic Agency at the time. “I read an interview with him where he says that because he was in a small country, he would have to find a niche that other people weren’t working in.”
—
The post Raphael Mechoulam, Israel’s ‘father of cannabis research,’ dies at 92 appeared first on Jewish Telegraphic Agency.
Uncategorized
A quiet diplomatic shift in the Middle East, with monumental consequences for Israel
Something significant is happening between Israel and Syria, and it deserves more attention than it is getting.
With the backing of the United States, Israeli and Syrian officials have agreed to create what they call a “joint fusion mechanism” — a permanent channel for coordination on intelligence, de-escalation, diplomacy and economic matters — during meetings in Paris. It appears to be the beginning of institutionalized contact between two countries that have formally been at war since 1948.
If this process continues, it will count as a genuine foreign-policy success for President Donald Trump’s administration.
To understand how profound that change would be, it is worth recalling the two countries’ shared history.
Israel and Syria — which the U.S. struck with a set of targeted attacks on the Islamic State on Saturday — have fought openly or by proxy for decades. Before 1967, Syrian artillery positions in the Golan Heights regularly shelled Israeli communities in the Hula Valley and around the Sea of Galilee. After Israel captured that region in 1967, the direct shelling stopped, but the conflict did not.
Syria remained formally committed to a state of war; Israel entrenched itself in the Golan Heights; both sides treated the frontier as a potential flashpoint to be managed carefully. After Egypt and Israel made peace in 1979, Syria became Israel’s most dangerous neighboring state.
A 1974 disengagement agreement created a United Nations-monitored buffer zone, which mostly ensured peace along the border, but did not resolve anything fundamental. In Lebanon, Israel and Syria backed opposing forces for years, and their air forces clashed briefly during the 1982 Lebanon War. Later, Iran’s growing role in Syria and Hezbollah’s military buildup added new threats. The Syrian civil war then destroyed basic state capacity and created precisely the kind of militia-rich environment Israel fears along its borders.
Now, with the dictator Bashar al-Assad gone and the former rebel leader Ahmed al-Sharaa in power, Syria is a broken country trying to stabilize. Sharaa’s past associations, disturbingly, include leadership of jihadist groups that were part of the wartime landscape in Syria. But today he governs a state facing economic collapse, infrastructure ruin and a population that needs jobs and basic services. His incentives are simple and powerful: ensure the survival of his regime, invite foreign investment, and secure relief from isolation and sanctions. Those goals point toward the U.S. and its partners, including Israel.
The Trump administration has made it clear that it wants to see new Syrian cooperation with Israel, with the suggestion that progress with Israel will become a gateway to international investment, and to a degree of political acceptance that Syria has lacked for years. Al-Sharaa’s willingness to engage is therefore not a mystery.
Israel’s motivations are also straightforward. After the Gaza war, Israel is facing a severe reputational problem. It is widely viewed abroad as reckless and excessively militarized. The government is under pressure over not only the conduct of the war but also the perception that it has no political strategy and relies almost exclusively on force. A diplomatic track with Syria allows Israel to present a very different picture: that of a country capable of negotiations with ideologically opposed neighbors, de-escalation, and regional cooperation.
There are significant security incentives, too.
Israel wants to limit Iran and Hezbollah’s influence in Syria. It wants a predictable northern border. It wants assurances regarding the Druze population in southern Syria — brethren to the Israeli Druze who are extremely loyal to the state, and who were outraged after a massacre of Syrian Druze followed the installation of al-Sharaa’s regime. It wants to ensure that no armed Syrian groups will tread near the Golan. A coordinated mechanism supervised by the U.S. offers a strong diplomatic way to address these issues.
The U.S. will benefit as well. The Trump team is eager to show that it can deliver lasting diplomatic achievements in the Middle East after the success of the Abraham Accords in Trump’s first term. A meaningful shift in Israel–Syria relations would be a very welcome addition, especially as the U.S.-brokered ceasefire in the Gaza war faces an uncertain future.
The main questions now are practical. Can the “joint fusion mechanism” function under pressure? What will happen when there is, almost inevitably, an incident — a drone downed, a militia clash, a cross-border strike? Will the new system effectively lower the temperature, or will it collapse at the first crisis?
Will Iran — facing its own profound internal political crisis — accept a Syria that coordinates with Israel under U.S. supervision, or will it work to undermine al-Sharaa? How will Hezbollah react if Damascus appears to move away from the axis of “resistance” and toward a security understanding with Israel?
How would an Israel-Syria deal impact Lebanon’s moribund efforts to dismantle Hezbollah’s military capacity? Al-Sharaa has already helped significantly by ending the transfer of weapons to Hezbollah from Iran through his territory. Might he also actively help with the disarming of the group?
No one should expect a full peace treaty soon. The question of possession of the Golan Heights probably remains a deal-breaker. Public opinion in Syria has been shaped by decades of official hostility to Israel, and Israeli politics is fragmented and volatile.
But diplomatic breakthroughs can confound expectations. They usually begin with mechanisms like this one, involving limited cooperation, routine contact and crisis management.
If this effort helps move the border from a zone of permanent tension to one of managed stability, that alone would be a major shift. It would also send a signal beyond the region: U.S. engagement still matters, and American pressure and incentives can still change behavior.
The post A quiet diplomatic shift in the Middle East, with monumental consequences for Israel appeared first on The Forward.
Uncategorized
Israel’s Netanyahu Hopes to ‘Taper’ Israel Off US Military Aid in Next Decade
Israeli Prime Minister Benjamin Netanyahu speaks to the press on Capitol Hill, Washington, DC, July 8, 2025. REUTERS/Evelyn Hockstein
Israeli Prime Minister Benjamin Netanyahu said in an interview published on Friday that he hopes to “taper off” Israeli dependence on US military aid in the next decade.
Netanyahu has said Israel should not be reliant on foreign military aid but has stopped short of declaring a firm timeline for when Israel would be fully independent from Washington.
“I want to taper off the military within the next 10 years,” Netanyahu told The Economist. Asked if that meant a tapering “down to zero,” he said: “Yes.”
Netanyahu said he told President Donald Trump during a recent visit that Israel “very deeply” appreciates “the military aid that America has given us over the years, but here too we’ve come of age and we’ve developed incredible capacities.”
In December, Netanyahu said Israel would spend 350 billion shekels ($110 billion) on developing an independent arms industry to reduce dependency on other countries.
In 2016, the US and Israeli governments signed a memorandum of understanding for the 10 years through September 2028 that provides $38 billion in military aid, $33 billion in grants to buy military equipment and $5 billion for missile defense systems.
Israeli defense exports rose 13 percent last year, with major contracts signed for Israeli defense technology including its advanced multi-layered aerial defense systems.
US Republican Senator Lindsey Graham, a staunch Israel supporter and close ally of Trump, said on X that “we need not wait ten years” to begin scaling back military aid to Israel.
“The billions in taxpayer dollars that would be saved by expediting the termination of military aid to Israel will and should be plowed back into the US military,” Graham said. “I will be presenting a proposal to Israel and the Trump administration to dramatically expedite the timetable.”
Uncategorized
In Rare Messages from Iran, Protesters ask West for Help, Speak of ‘Very High’ Death Toll
Protests in Tehran. Photo: Iran Photo from social media used in accordance with Clause 27a of the Copyright Law, via i24 News
i24 News – Speaking to Western media from beyond the nationwide internet blackout imposed by the Islamic regime, Iranian protesters said they needed support amid a brutal crackdown.
“We’re standing up for a revolution, but we need help. Snipers have been stationed behind the Tajrish Arg area [a neighborhood in Tehran],” said a protester in Tehran speaking to the Guardian on the condition of anonymity. He added that “We saw hundreds of bodies.”
Another activist in Tehran spoke of witnessing security forces firing live ammunition at protesters resulting in a “very high” number killed.
On Friday, TIME magazine cited a Tehran doctor speaking on condition of anonymity that just six hospitals in the capital recorded at least 217 killed protesters, “most by live ammunition.”
Speaking to Reuters on Saturday, Setare Ghorbani, a French-Iranian national living in the suburbs of Paris, said that she became ill from worry for her friends inside Iran. She read out one of her friends’ last messages before losing contact: “I saw two government agents and they grabbed people, they fought so much, and I don’t know if they died or not.”