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Hereditary cancers aren’t just a women’s problem. Jewish men need to take precautions too.

Bill Harris, a veteran Los Angeles photojournalist, didn’t think much of it when one morning in 2012 he woke up and found a tiny blood spot on the T-shirt he’d slept in. The next morning, he found blood in the same place on his chest — and went straight to his computer.

“Online, I could find only three things that would cause a man’s nipple to discharge blood: being an avid runner, which I wasn’t; having a subtropical fungus, which I didn’t; and breast cancer,” he said. “That was a pretty big shock.”

Harris, then just a few weeks shy of his 61st birthday, immediately called his doctor, who ordered a mammogram and ultrasound. They confirmed a cancerous growth in his right breast. Ten days later, a biopsy came back positive. The next month Harris got a right mastectomy, followed by the removal of his left breast half a year later.

“I walked into a woman’s imaging center and had to get into a pink paper robe,” he recalled. “All the women in the waiting room were staring at me.”

Like many other Ashkenazi men, Harris never had considered that he might have been born with a harmful mutation of the BRCA gene, which elevates the risk not only of breast cancer, but also of melanoma and prostate, ovarian and pancreatic cancer.

“Hundreds of other mutations in the BRCA gene are just as dangerous, but they’re not specific to Ashkenazim,” said Dr. Robert Sidlow, director of the Male BRCA Genetic Risk Program at New York’s Memorial Sloan Kettering Cancer Center. About 1 in 40 Ashkenazi Jews (those of Eastern European descent) carries the harmful mutation, compared to about 1 in 400 in the general population.

“The vast majority of patients I see are relatives of women who have breast or ovarian cancer and then get tested,” he said. Of BRCA mutation carriers, Sidlow added, “Most men are pretty happy to enroll in some kind of surveillance program once they get over the initial shock.”

Sidlow is on the Men’s Leadership Council at Sharsheret, the national Jewish nonprofit organization that educates the community about cancer risks and supports those with breast cancer and ovarian cancer.

Elana Silber, CEO of Sharsheret (Hebrew for “chain”), says it’s crucial that men with a family history of cancer undergo genetic counseling screening for BRCA and other hereditary cancer mutations.

Genetic testing is possible via a standard blood or saliva sample.

While Sharsheret is primarily considered a women’s organization, it has been using November — nicknamed Movember for its focus on men’s health — for an awareness campaign focused on Jewish men’s cancer risks.

“This is not only a women’s issue,” Silber said. “Family history is so important. When a man shares his family history with his doctor, he may not realize that he should mention that his mother had breast cancer or that his sister had ovarian cancer, as these are not generally ‘men’s diseases.’ They are not aware that these cancers could mean that they themselves are at increased risk for cancer and that they can pass on these mutations to the next generation – their daughters and their sons.”

If someone discovers he (or she) is a carrier of one of the genetic mutations with elevated cancer risks — not just BRCA but also such mutations as ATM, TP53, CHEK2, and PALB2 — there are various precautions they can take for themselves and their children. They can monitor their own health more closely, they can get encourage their children to test to see if they are carriers and, for any future children, take steps to prevent the mutated genes from being passed down.

For example, couples can conceive via in vitro fertilization, or IVF, and then test the embryos before implantation to ensure that only those unaffected by the genetic mutation are implanted.

While most women are aware of the risks of breast cancer, men generally are not — even though the disease strikes 2,500 men in the U.S. every year and kills about 500 of them, according to Sidlow. About 1-2% of men with the BRCA1 mutation and 6-7% of men with the BRCA2 mutation will develop cancer by age 80.

“This is why we recommend periodic mammograms starting at about age 50 for men who carry a BRCA2 mutation,” Sidlow said. “We like to educate these men on how to check their chests once a month and have a clinician do a breast checkup on them once a year.”

Since the BRCA1 and BRCA2 mutations also make prostate cancer more likely, men with either mutation should get PSA (prostate-specific antigen) levels in their blood tested annually beginning at age 40, rather than 50, the age at which screening generally begins, Sidlow said.

Sharsheret has been promoting the importance of learning one’s family history, genetic counseling and screening among both men and women. The 20-year-old organization also runs various peer support networks, offers financial assistance to cancer patients, provides mental health counseling and guidance to patients, caregivers, and their friends, and seeks to educate the broader Jewish community about cancer risks and support.

Peggy Cottrell, a certified genetic counselor at Sharsheret, said men in general are more reluctant to get regular checkups than women.

Ashkenazi Jewish men are at elevated risk not just of breast and prostate cancer but also of pancreatic cancer. Pancreatic cancer is particularly difficult because it’s tough to detect early enough and hard to treat. The five-year survival rate is only 11%. About 2% of BRCA1 carriers and 4% of BRCA2 carriers will develop pancreatic cancer, Sidlow estimated.

“Usually by the time pancreas cancer is clinically detected it has already spread microscopically to the liver,” Sidlow said. “But pancreas cancer is potentially curable if caught when the tumor is extremely small.”

Even among those with elevated risks, certain behaviors can improve one’s odds, such as avoiding obesity, smoking and excessive alcohol consumption.

Harris, the California photojournalist, is still fighting at age 71. While he overcame breast cancer 10 years ago, last year he was diagnosed with ampullary cancer, a rare disease related to his BRCA2 status that was discovered thanks to his participation in a UCLA study. Surgeons have removed his gall bladder, half his pancreas and part of his small intestine, and he has had to endure eight rounds of chemotherapy.

“I’m still working through the aftereffects of the chemo. I have to eat smaller quantities than before and take enzymes to supplement my digestive processes,” Harris said.

Meanwhile, his 37-year-old son discovered that he, too, carries the BRCA2 mutation, and he had a double prophylactic mastectomy and reconstruction at age 30 — just to be on the safe side.

“If there’s any history of breast, ovarian or prostate cancer in your family, get tested genetically so that you’re informed,” Harris advised. “Diagnoses happen way too late for men, and the danger is too big.”


The post Hereditary cancers aren’t just a women’s problem. Jewish men need to take precautions too. appeared first on Jewish Telegraphic Agency.

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120th anniversary of the Forverts advice column “Bintel Brief”

מזל־טובֿ! דעם 20סטן יאַנואַר 2026 איז געוואָרן 120 יאָר זינט דער גרינדונג פֿון „אַ בינטל בריוו“ — דער עצות־רובריק פֿונעם פֿאָרווערטס. די רובריק איז פֿאַרלייגט געוואָרן פֿונעם גרינדער און לאַנגיאָריקן שעף־רעדאַקטאָר אַב קאַהאַן אין 1906.

כּדי אָפּצומערקן דעם יום־טובֿ ברענגען מיר אײַך צוויי זאַכן:

• ערשטנס, אַן אַרטיקל וועגן אַ טשיקאַווען בריוו וואָס איז אָנגעקומען אין דער פֿאָרווערטס־רעדאַקציע אין יאַנואַר 1949, פֿון אַ לייענער וועמעס זון האָט חתונה געהאַט מיט אַ קריסטלעכער פֿרוי

• צווייטנס, אַ פֿאָרווערטס־ווידעאָ אויף ייִדיש וועגן דער געשיכטע פֿון „אַ בינטל בריוו“, מיטן געוועזענעם פֿאָרווערטס־רעדאַקטאָר באָריס סאַנדלער און דער פֿאָרווערטס־אַרכיוויסטקע חנה פּאָלאַק.

 

 

The post 120th anniversary of the Forverts advice column “Bintel Brief” appeared first on The Forward.

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Report: Khamenei Moved to Underground Bunker in Tehran

Iran’s Supreme Leader Ayatollah Ali Khamenei speaks in a televised message, after the ceasefire between Iran and Israel, in Tehran, Iran, June 26, 2025. Photo: Office of the Iranian Supreme Leader/WANA (West Asia News Agency)/Handout via REUTERS

i24 NewsAmid tense expectation of US strike on key assets of the Islamic regime, Iran’s Supreme Leader Ali Khamenei was moved into a special underground bunker in Tehran, the Iran International website reported on Saturday.

The report further added that the supreme leader’s third son Masoud Khamenei has taken over day-to-day management of the leader’s office, functioning as the de facto main channel for coordination vis-à-vis the executive branches of the government and the security forces.

The report describes Khamenei’s hideout as a “fortified site with interconnected tunnels.”

On Thursday US President Donald Trump said that a “massive” naval force was heading toward Iran.

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Israel, Syria to Finalize US-Brokered Security Deal ‘Soon,’ as ‘Developments Accelerate Noticeably’

Syria’s interim President Ahmed al-Sharaa speaks during a Ministerial formation of the government of the Syrian Arab Republic, in Damascus, Syria, March 29, 2025. Photo: REUTERS/Khalil Ashawi

i24 NewsSyrian and Israeli officials are expected to meet soon under US mediation, perhaps in Paris, to finalize a security agreement between Damascus and Jerusalem, a source close to Syrian President Ahmed al-Sharaa told i24NEWS on Saturday.

According to the Syrian source, the talks will also focus on various potential joint strategic and economic projects in the buffer zones between the two countries.

“There is very optimistic talk suggesting the possibility of even opening an Israeli embassy in Damascus before the end of this year, given the significant progress in the prospect of Syria joining the Abraham Accords,” the source said.

The original Syrian plan was limited to a security agreement and the opening of an Israeli liaison office in Damascus without diplomatic status, the source tells me. “But developments are accelerating noticeably under pressure from the United States, and specifically by President Trump, and amid growing Syrian openness.”

If Damascus manages to reach an integration agreement with the Druze in southern Syria, similar to its agreement with the Kurds in the northeast, and Israel commits to respecting Syria’s unity and territorial integrity, then al-Sharaa would be open to elevate the status of the agreement with Israel to more than just a security agreement, to also include diplomatic relations and an Israeli embassy in Damascus.

“The al-Sharaa government believes that a viable compromise to advance a peace process with Israel would include a 25-year lease for the Golan Heights, similar to the one Jordan previously signed with Israel over the border enclaves, turning it into a ‘Garden of Peace” of joint economic ventures,” the source said.

The source close to al-Sharaa also tells me that US President Trump is seeking to bring Israeli Prime Minister Netanyahu and President Al-Sharaa together for a peace agreement signing ceremony.

It should be noted that Israel has repeatedly rejected returning any part of the Golan Heights, let alone the entire territory.

On another front, the source stated that Damascus intends to adopt a new local administration system based on expanded administrative decentralization to enhance participation in local communities across all Syrian governorates.

According to the source, this solution would resolve persisting disputes with the Druze, Kurds, Alawites, and other minorities. A new Syrian government is expected to be formed within the next three months, the source added.

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