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Hereditary cancers aren’t just a women’s problem. Jewish men need to take precautions too.
Bill Harris, a veteran Los Angeles photojournalist, didn’t think much of it when one morning in 2012 he woke up and found a tiny blood spot on the T-shirt he’d slept in. The next morning, he found blood in the same place on his chest — and went straight to his computer.
“Online, I could find only three things that would cause a man’s nipple to discharge blood: being an avid runner, which I wasn’t; having a subtropical fungus, which I didn’t; and breast cancer,” he said. “That was a pretty big shock.”
Harris, then just a few weeks shy of his 61st birthday, immediately called his doctor, who ordered a mammogram and ultrasound. They confirmed a cancerous growth in his right breast. Ten days later, a biopsy came back positive. The next month Harris got a right mastectomy, followed by the removal of his left breast half a year later.
“I walked into a woman’s imaging center and had to get into a pink paper robe,” he recalled. “All the women in the waiting room were staring at me.”
Like many other Ashkenazi men, Harris never had considered that he might have been born with a harmful mutation of the BRCA gene, which elevates the risk not only of breast cancer, but also of melanoma and prostate, ovarian and pancreatic cancer.
“Hundreds of other mutations in the BRCA gene are just as dangerous, but they’re not specific to Ashkenazim,” said Dr. Robert Sidlow, director of the Male BRCA Genetic Risk Program at New York’s Memorial Sloan Kettering Cancer Center. About 1 in 40 Ashkenazi Jews (those of Eastern European descent) carries the harmful mutation, compared to about 1 in 400 in the general population.
“The vast majority of patients I see are relatives of women who have breast or ovarian cancer and then get tested,” he said. Of BRCA mutation carriers, Sidlow added, “Most men are pretty happy to enroll in some kind of surveillance program once they get over the initial shock.”
Sidlow is on the Men’s Leadership Council at Sharsheret, the national Jewish nonprofit organization that educates the community about cancer risks and supports those with breast cancer and ovarian cancer.
Elana Silber, CEO of Sharsheret (Hebrew for “chain”), says it’s crucial that men with a family history of cancer undergo genetic counseling screening for BRCA and other hereditary cancer mutations.
Genetic testing is possible via a standard blood or saliva sample.
While Sharsheret is primarily considered a women’s organization, it has been using November — nicknamed Movember for its focus on men’s health — for an awareness campaign focused on Jewish men’s cancer risks.
“This is not only a women’s issue,” Silber said. “Family history is so important. When a man shares his family history with his doctor, he may not realize that he should mention that his mother had breast cancer or that his sister had ovarian cancer, as these are not generally ‘men’s diseases.’ They are not aware that these cancers could mean that they themselves are at increased risk for cancer and that they can pass on these mutations to the next generation – their daughters and their sons.”
If someone discovers he (or she) is a carrier of one of the genetic mutations with elevated cancer risks — not just BRCA but also such mutations as ATM, TP53, CHEK2, and PALB2 — there are various precautions they can take for themselves and their children. They can monitor their own health more closely, they can get encourage their children to test to see if they are carriers and, for any future children, take steps to prevent the mutated genes from being passed down.
For example, couples can conceive via in vitro fertilization, or IVF, and then test the embryos before implantation to ensure that only those unaffected by the genetic mutation are implanted.
While most women are aware of the risks of breast cancer, men generally are not — even though the disease strikes 2,500 men in the U.S. every year and kills about 500 of them, according to Sidlow. About 1-2% of men with the BRCA1 mutation and 6-7% of men with the BRCA2 mutation will develop cancer by age 80.
“This is why we recommend periodic mammograms starting at about age 50 for men who carry a BRCA2 mutation,” Sidlow said. “We like to educate these men on how to check their chests once a month and have a clinician do a breast checkup on them once a year.”
Since the BRCA1 and BRCA2 mutations also make prostate cancer more likely, men with either mutation should get PSA (prostate-specific antigen) levels in their blood tested annually beginning at age 40, rather than 50, the age at which screening generally begins, Sidlow said.
Sharsheret has been promoting the importance of learning one’s family history, genetic counseling and screening among both men and women. The 20-year-old organization also runs various peer support networks, offers financial assistance to cancer patients, provides mental health counseling and guidance to patients, caregivers, and their friends, and seeks to educate the broader Jewish community about cancer risks and support.
Peggy Cottrell, a certified genetic counselor at Sharsheret, said men in general are more reluctant to get regular checkups than women.
Ashkenazi Jewish men are at elevated risk not just of breast and prostate cancer but also of pancreatic cancer. Pancreatic cancer is particularly difficult because it’s tough to detect early enough and hard to treat. The five-year survival rate is only 11%. About 2% of BRCA1 carriers and 4% of BRCA2 carriers will develop pancreatic cancer, Sidlow estimated.
“Usually by the time pancreas cancer is clinically detected it has already spread microscopically to the liver,” Sidlow said. “But pancreas cancer is potentially curable if caught when the tumor is extremely small.”
Even among those with elevated risks, certain behaviors can improve one’s odds, such as avoiding obesity, smoking and excessive alcohol consumption.
Harris, the California photojournalist, is still fighting at age 71. While he overcame breast cancer 10 years ago, last year he was diagnosed with ampullary cancer, a rare disease related to his BRCA2 status that was discovered thanks to his participation in a UCLA study. Surgeons have removed his gall bladder, half his pancreas and part of his small intestine, and he has had to endure eight rounds of chemotherapy.
“I’m still working through the aftereffects of the chemo. I have to eat smaller quantities than before and take enzymes to supplement my digestive processes,” Harris said.
Meanwhile, his 37-year-old son discovered that he, too, carries the BRCA2 mutation, and he had a double prophylactic mastectomy and reconstruction at age 30 — just to be on the safe side.
“If there’s any history of breast, ovarian or prostate cancer in your family, get tested genetically so that you’re informed,” Harris advised. “Diagnoses happen way too late for men, and the danger is too big.”
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What happened during the 2025 Israel-Iran war? A timeline.
(JTA) — The U.S.-Israeli military attack on Iran that launched early Saturday morning comes eight months after the last Israel-Iran war, in June 2025.
As we wait to see what happens in the current war, here’s a look back at how the 2025 conflict played out, from uneasy tensions to U.S. intervention to a grim death toll for Israelis.
- April 2024: First exchange of missiles between Israel and Iran in the 45-year history of the Islamic Republic:
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May-June 2025: Tensions built in the weeks and days leading up to the attack, with the international community condemning Iran’s failure to abide by past nuclear agreements. Diplomatic efforts stalled as officials on all sides signaled that a direct confrontation was possible.
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June 13: Israel launches its attack on Iranian nuclear facilities and ballistic missile program, followed shortly by a warning from Israeli Prime Minister Benjamin Netanyahu that retaliation by Iran was “expected in the immediate future.”
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June 13—: As Israel continues to pummel targets in Iran, Tehran counter-attacks, sending missiles almost nightly. Twenty-eight people are killed in Israel, including four women in an Arab town in northern Israel; a Ukrainian family that had come for cancer treatment for their daughter; and an activist at her home in Beersheba. Many others lost their homes. Flights, schools and workplaces are all massively disrupted.
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June 18: Donald Trump, who had run on a platform of opposing all war, sends mixed signals about whether he will jump in, as the Israelis clearly hoped he would. Trump tells reporters days into the conflict that “nobody knows what I’m going to do.”
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June 21: The United States joins the fight, striking three sites associated with Iran’s nuclear program, including Fordow, Natanz and Esfahan, alongside Israeli forces. The deeply buried facilities were seen as impossible to target without U.S. arms.
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June 23: Trump announces a ceasefire on social media. Iran’s Supreme National Security Council claims victory following the announcement despite striking Israel in its immediate wake. Israel does not say it had acceded to a ceasefire until many hours later.
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Aftermath: The extent of damage to the Iranian regime was unclear. Even on Saturday, as Trump renewed the fight against the Islamic Republic following negotiations that he said had not been satisfactory, he said last year’s strikes had “obliterated” Iran’s nuclear program. But the regime was rebuilding it, he and other observers said, and Iran had reportedly stockpiled more missiles than it had before the 2025 war. And the regime remained intact, clamping down a domestic protest movement by killing tens of thousands of protesters within 48 hours last month. Trump initially threatened to strike over the mass killings but did not.
This article originally appeared on JTA.org.
The post What happened during the 2025 Israel-Iran war? A timeline. appeared first on The Forward.
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Sirens, shelters and an empty Old City: Jerusalem rattled on the first day of war with Iran
(JTA) — JERUSALEM — Jacob Phillips’ first trip to Israel from his home in Germany was in 2023, to visit Holocaust survivors in Tel Aviv as part of a university program. It was cut short by the Oct. 7 Hamas-led attack, which forced him to leave the country.
He returned with his girlfriend this month to see the sites he missed. “Because the last trip, it was a harsh cut,” he said. “That’s why we came back, to visit the people I met here in Israel.”
On Saturday, Phillips and his girlfriend Michelle were among the very few people walking the streets in Jerusalem as another war unfolded, with Iran. The war, which began when Israel and the United States together attacked Iran early Saturday, had already sent them multiple times to shelters and scrambled their departure plans for next Thursday. Ben Gurion Airport is closed until at least March 7.
Phillips said he was in touch with the German consulate and felt safe in Jerusalem despite the incoming missiles, citing Israel’s Iron Dome air defense system. He said he remained happy to be in Israel.
“I wanted to come here to learn about the Jewish experience, especially as a German, and I feel like I have gotten to see so much of it,” Phillips said.
While missile impacts rocked Tel Aviv and elsewhere in Israel, an eerie calm pervaded the streets of Jerusalem on Saturday, extreme even for Shabbat, as residents hunkered down at home between the sirens that indicated that war with Iran had begun anew. The sirens scattered the prayer services that dot the holy city and disrupted plans for shared meals.
The gates of the Old City were closed by Israeli police to everyone but residents. A crowd of Hasidic Jews argued with officers, petitioning for entry to pray at the Western Wall but ultimately giving up and turning back.
One resident who ventured out between air raid alerts said the assault had provided “pauses just long enough to walk up the stairs before heading back [to the shelter] again.”
Those who braved journeys away from their homes offered a general consensus that the war would be significantly worse this time around, only nine months after a 12-day war that led to the deaths of 32 Israelis. In that conflict, Iran launched more than 500 ballistic missiles at Israel and targets throughout the Middle East in retaliation for strikes that Israel initiated and the United States joined.
This time is indeed different. President Donald Trump and Prime Minister Benjamin Netanyahu are gunning for regime change and said they believed Iran’s supreme leader, Ayatollah Ali Khamenei, had been killed in an opening salvo. Sensing an existential threat, the Islamic Republic of Iran has already escalated its response, using its firepower against not only Israel but U.S. targets throughout the Middle East.
Richard Weiner and Rolly Feld had been in Nahariya, in Israel’s north, until Saturday morning. When the sirens began, they drove back to Jerusalem in the hope they would be safer in the city and farther from significant military targets for the Iranian regime, including the port of Haifa, which was struck by an Iranian barrage at 10 a.m.
Feld recounted that while driving down Route 4 toward Jerusalem, it felt as if they were being chased by missiles. Periodically, another batch of air raid alerts would sound, forcing them to shelter in tunnels along the highway.
Feld said he would have preferred to continue driving, contrary to the advice of Israeli authorities who recommend pulling over and lying flat to avoid exposure to shrapnel from missile impacts.
“My wife wanted all the time to stick to the guidelines, to stop the car and stay away, and I keep driving fast then stopped in the tunnels. It’s a compromise,” Feld said.
Weiner, who grew up in Israel but has lived as an adult in South Africa, was critical of Netanyahu’s decision to launch the strikes.
“What he’s doing is horrible for the Iranian people and it’s horrible for the people over here. The government is pushing for this; the people are not.” Weiner identified himself as “something of a pacifist,” adding, “We have to look for other ways of dealing with the Iranian government, as irrational as they are. We should be supporting the people who are protesting and not trying to topple the government by killing the leadership.”
Weiner and Feld bantered back and forth on a sidewalk in the leafy neighborhood of Rehavia, discussing the possibility of further escalation and whether it was Israel’s place to intervene on behalf of the Iranian people — if that was indeed part of the calculus.
Weiner concluded, “I have a love-hate relationship with this country. I come back and this happens again. This is clearly not the answer. Many people will be killed, and it’s horrible that tens of thousands have been killed due to their dissent, but how does this help?”
The question of whether the war would succeed in the U.S.-Israeli ambition of achieving regime change in Iran was a preoccupation of many of those who were out and about.
“The chance of actual change is so low,” said Ishay, 44, a Jerusalem resident. “Like in Israel, there is such a strong contingent of those with radical beliefs in Iran. Even if the regime is toppled, who will replace Khamenei?”
Information was hard to come by throughout the day, though over time it became clear that missile impacts had been confirmed in multiple locations, including Bnei Brak, where Magen David Adom treated people who were wounded. By overnight, it was clear that one woman had been killed and another man had been seriously wounded in Tel Aviv.
The war comes as Israel prepares to celebrate Purim, a Jewish holiday commemorating the overthrow of an oppressive Persian regime, offering a powerful parallel for the current moment.
In the lead-up to the holiday, two Israelis stood talking down the street, seemingly unconcerned by the sirens, both in costume — one wearing a sombrero, the other dressed as a clown.
Yael, who lives in Rehavia, was walking her dog, Lucky, in Meir Sherman Garden Park in central Jerusalem.
“We’ve just come to expect this. I am raising my children here in Israel, but sometimes I wonder if there is a future here,” she said.
For Phillips, the fact that both of his visits to Israel have been derailed by two different conflicts did not dampen his support for Israel’s decision to launch the attacks on Iran.
“It’s time to change the regime there because of the nuclear weapons; it’s important to have this under control,” he said. “For Israel, it will be a hard time, I think, but nothing is free. You have to pay with something.”
This article originally appeared on JTA.org.
The post Sirens, shelters and an empty Old City: Jerusalem rattled on the first day of war with Iran appeared first on The Forward.
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Israel says Iranian supreme leader Khamenei killed during strikes on Tehran
(JTA) — Ayatollah Ali Khamenei, Iran’s supreme leader, was killed Saturday morning during a joint U.S.-Israeli strike that hit targets throughout the country, Israeli officials have announced.
In a televised address late Saturday, Prime Minister Benjamin Netanyahu said there were “growing signs” that Khamenei had been killed during an Israeli strike on his compound in Tehran. Shortly after the address, Israeli officials told Axios and the Associated Press that they had confirmed his death.
The alleged death of Khamenei, 86, who has ruled Iran since 1989 and was one of the world’s longest-serving authoritarian leaders, would serve as a major blow to the Islamic Republic regime, which Netanyahu and President Donald Trump both said they sought to topple in the strikes.
Trump cautiously confirmed the reports of Khamenei’s death on Saturday, telling NBC News about the Israeli report, “We feel that that is a correct story.” The president also told ABC correspondent Rachel Scott, “I don’t want to say anything definitively until I see things but we believe he is, and much of their leaders are gone.”
Iran appeared to deny claims that Khamenei had died on Saturday, with Iranian state media reporting that a source close to Khamenei’s office said, “I can tell you with confidence that the leader of the revolution is steadfast and firm in commanding the field,” according to Reuters.
Khamenei reportedly appointed a deputy to succeed him ahead of the strikes. But the CIA has assessed that he may be replaced by hardline figures from the Islamic Revolutionary Guard, according to Reuters.
Trump said he believed a large number of other Iranian officials were killed in the initial strikes, but neither he nor Israeli officials immediately named other officials they believed had been killed.
This article originally appeared on JTA.org.
The post Israel says Iranian supreme leader Khamenei killed during strikes on Tehran appeared first on The Forward.
