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Hereditary cancers aren’t just a women’s problem. Jewish men need to take precautions too.

Bill Harris, a veteran Los Angeles photojournalist, didn’t think much of it when one morning in 2012 he woke up and found a tiny blood spot on the T-shirt he’d slept in. The next morning, he found blood in the same place on his chest — and went straight to his computer.

“Online, I could find only three things that would cause a man’s nipple to discharge blood: being an avid runner, which I wasn’t; having a subtropical fungus, which I didn’t; and breast cancer,” he said. “That was a pretty big shock.”

Harris, then just a few weeks shy of his 61st birthday, immediately called his doctor, who ordered a mammogram and ultrasound. They confirmed a cancerous growth in his right breast. Ten days later, a biopsy came back positive. The next month Harris got a right mastectomy, followed by the removal of his left breast half a year later.

“I walked into a woman’s imaging center and had to get into a pink paper robe,” he recalled. “All the women in the waiting room were staring at me.”

Like many other Ashkenazi men, Harris never had considered that he might have been born with a harmful mutation of the BRCA gene, which elevates the risk not only of breast cancer, but also of melanoma and prostate, ovarian and pancreatic cancer.

“Hundreds of other mutations in the BRCA gene are just as dangerous, but they’re not specific to Ashkenazim,” said Dr. Robert Sidlow, director of the Male BRCA Genetic Risk Program at New York’s Memorial Sloan Kettering Cancer Center. About 1 in 40 Ashkenazi Jews (those of Eastern European descent) carries the harmful mutation, compared to about 1 in 400 in the general population.

“The vast majority of patients I see are relatives of women who have breast or ovarian cancer and then get tested,” he said. Of BRCA mutation carriers, Sidlow added, “Most men are pretty happy to enroll in some kind of surveillance program once they get over the initial shock.”

Sidlow is on the Men’s Leadership Council at Sharsheret, the national Jewish nonprofit organization that educates the community about cancer risks and supports those with breast cancer and ovarian cancer.

Elana Silber, CEO of Sharsheret (Hebrew for “chain”), says it’s crucial that men with a family history of cancer undergo genetic counseling screening for BRCA and other hereditary cancer mutations.

Genetic testing is possible via a standard blood or saliva sample.

While Sharsheret is primarily considered a women’s organization, it has been using November — nicknamed Movember for its focus on men’s health — for an awareness campaign focused on Jewish men’s cancer risks.

“This is not only a women’s issue,” Silber said. “Family history is so important. When a man shares his family history with his doctor, he may not realize that he should mention that his mother had breast cancer or that his sister had ovarian cancer, as these are not generally ‘men’s diseases.’ They are not aware that these cancers could mean that they themselves are at increased risk for cancer and that they can pass on these mutations to the next generation – their daughters and their sons.”

If someone discovers he (or she) is a carrier of one of the genetic mutations with elevated cancer risks — not just BRCA but also such mutations as ATM, TP53, CHEK2, and PALB2 — there are various precautions they can take for themselves and their children. They can monitor their own health more closely, they can get encourage their children to test to see if they are carriers and, for any future children, take steps to prevent the mutated genes from being passed down.

For example, couples can conceive via in vitro fertilization, or IVF, and then test the embryos before implantation to ensure that only those unaffected by the genetic mutation are implanted.

While most women are aware of the risks of breast cancer, men generally are not — even though the disease strikes 2,500 men in the U.S. every year and kills about 500 of them, according to Sidlow. About 1-2% of men with the BRCA1 mutation and 6-7% of men with the BRCA2 mutation will develop cancer by age 80.

“This is why we recommend periodic mammograms starting at about age 50 for men who carry a BRCA2 mutation,” Sidlow said. “We like to educate these men on how to check their chests once a month and have a clinician do a breast checkup on them once a year.”

Since the BRCA1 and BRCA2 mutations also make prostate cancer more likely, men with either mutation should get PSA (prostate-specific antigen) levels in their blood tested annually beginning at age 40, rather than 50, the age at which screening generally begins, Sidlow said.

Sharsheret has been promoting the importance of learning one’s family history, genetic counseling and screening among both men and women. The 20-year-old organization also runs various peer support networks, offers financial assistance to cancer patients, provides mental health counseling and guidance to patients, caregivers, and their friends, and seeks to educate the broader Jewish community about cancer risks and support.

Peggy Cottrell, a certified genetic counselor at Sharsheret, said men in general are more reluctant to get regular checkups than women.

Ashkenazi Jewish men are at elevated risk not just of breast and prostate cancer but also of pancreatic cancer. Pancreatic cancer is particularly difficult because it’s tough to detect early enough and hard to treat. The five-year survival rate is only 11%. About 2% of BRCA1 carriers and 4% of BRCA2 carriers will develop pancreatic cancer, Sidlow estimated.

“Usually by the time pancreas cancer is clinically detected it has already spread microscopically to the liver,” Sidlow said. “But pancreas cancer is potentially curable if caught when the tumor is extremely small.”

Even among those with elevated risks, certain behaviors can improve one’s odds, such as avoiding obesity, smoking and excessive alcohol consumption.

Harris, the California photojournalist, is still fighting at age 71. While he overcame breast cancer 10 years ago, last year he was diagnosed with ampullary cancer, a rare disease related to his BRCA2 status that was discovered thanks to his participation in a UCLA study. Surgeons have removed his gall bladder, half his pancreas and part of his small intestine, and he has had to endure eight rounds of chemotherapy.

“I’m still working through the aftereffects of the chemo. I have to eat smaller quantities than before and take enzymes to supplement my digestive processes,” Harris said.

Meanwhile, his 37-year-old son discovered that he, too, carries the BRCA2 mutation, and he had a double prophylactic mastectomy and reconstruction at age 30 — just to be on the safe side.

“If there’s any history of breast, ovarian or prostate cancer in your family, get tested genetically so that you’re informed,” Harris advised. “Diagnoses happen way too late for men, and the danger is too big.”


The post Hereditary cancers aren’t just a women’s problem. Jewish men need to take precautions too. appeared first on Jewish Telegraphic Agency.

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Iran Supreme Leader Says Will Not Yield as Protests Simmer and US Threatens

Iran’s Supreme Leader Ayatollah Ali Khamenei speaks during a meeting in Tehran, Iran January 3, 2026. Office of the Iranian Supreme Leader/WANA (West Asia News Agency)/Handout via REUTERS

Iran’s Supreme Leader Ayatollah Ali Khamenei vowed not to yield after US President Donald Trump threatened to come to the aid of protesters, as rights groups reported a sharp rise in arrests following days of unrest sparked by soaring inflation.

Speaking in a recorded appearance on Saturday, Khamenei said the Islamic Republic “will not yield to the enemy” and that rioters should be “put in their place.”

State-affiliated media reported three deaths on Saturday, with rights groups saying more than 10 had already died in demonstrations across Iran since Sunday as the collapsing rial currency hits an economy already undermined by sanctions.

ECONOMIC CRISIS

Videos circulating on social media, which Reuters could not immediately verify, purported to show protests in southern and western Iran. In one, marchers called on other Iranians to come onto the streets, chanting “We don’t want spectators: join us”.

Mehr and Fars news agencies, both state affiliated, reported that a security forces member and two demonstrators were killed in Malekshahi, a western town, when what they called armed protesters tried to enter a police station.

Authorities have attempted to maintain a dual approach to the unrest, saying protests over the economy are legitimate and will be met by dialogue, while meeting some demonstrations with tear gas amid violent street confrontations.

“The bazaaris were right. They are right to say they cannot do business in these conditions,” said Khamenei, referring to market traders’ concerns over the currency slide.

“We will speak with the protesters but talking to rioters is useless. Rioters should be put in their place,” he added.

Reports of violence have centered on small cities in Iran’s western provinces, where several people have been killed, according to state media and rights groups. Authorities have said two members of the security services had died and more than a dozen were injured in the unrest.

Hengaw, a Kurdish rights group, said late on Friday that it had identified 133 people arrested, an increase of 77 from the previous day.

Trump on Friday said the US was “locked and loaded and ready to go” but did not specify what action it might take against Iran, where it carried out airstrikes last summer, joining an Israeli campaign targeting Iran’s nuclear sites and military leaders.

The threat of action adds to the pressure on Iran’s leaders as they navigate one of the most difficult periods in decades, with the sanctions-hit economy shrinking and the government struggling to provide water and electricity in some regions.

Iran has suffered a succession of major strategic blows to its regional position since the start of the war in Gaza in 2023 between its ally Hamas and Israel.

Israeli strikes hammered Iran’s strongest regional partner Hezbollah. Tehran’s close ally Bashar al-Assad was ousted in Syria. The Israeli and US assault strikes on Iran set back the expensive atomic program and killed senior military leaders, revealing extensive penetration of Tehran’s upper echelons.

FLARING VIOLENCE

The protests are the biggest since mass nationwide demonstrations in late 2022 over the death in custody of Kurdish woman Mahsa Amini. This week’s demonstrations have not matched those in scale, but still represent the toughest domestic test for authorities in three years.

Rights groups such as Hengaw and activists posting on social media reported continued protests and violence by security forces across Iran, while state-affiliated media reported what it called attacks on property by infiltrators “in the name of protest.”

State television reported arrests in western and central Iran and near the capital Tehran, including of people accused of manufacturing petrol bombs and home-made pistols.

Numerous social media posts overnight said there had been unrest in a number of cities and towns, as well as three districts of Tehran.

Reuters could not immediately verify the reports by rights groups, state media or social media accounts.

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Trump Says US Oil Companies Will Spend Billions in Venezuela

A photograph posted by US President Donald Trump on his Truth Social account shows him sitting next to CIA Director John Ratcliffe and US Secretary of State Marco Rubio as they watch the US military operation in Venezuela, January 3, 2026. Photo: @realDonaldTrump/Handout via REUTERS

President Donald Trump said that American oil companies were prepared to enter Venezuela and invest to restore production in the South American country, an announcement that came just hours after Nicolás Maduro was captured and removed by US forces.

“We’re going to have our very large US oil companies, the biggest anywhere in the world, go in, spend billions of dollars, fix the badly broken infrastructure, oil infrastructure, and start making money for the country,” Trump said on Saturday.

While Chevron is the only American major with current operations in Venezuela, Exxon Mobil and ConocoPhillips, among others, have storied histories in the country. The American Petroleum Institute, the largest US oil trade group, said on Saturday it was monitoring the emerging situation.

“We’re closely watching developments involving Venezuela, including the potential implications for global energy markets,” an API spokesperson told Reuters.

Chevron, which exports around 150,000 bpd of crude from Venezuela to the US Gulf Coast, said it is focused on the safety and wellbeing of its employees, in addition to the integrity of its assets.

“We continue to operate in full compliance with all relevant laws and regulations,” a Chevron spokesperson said in an emailed response to questions.

Top oilfield service companies SLB, Baker Hughes, Halliburton and Weatherford did not immediately respond to requests for comment. Exxon and Conoco did not immediately respond to questions from Reuters.

Trump’s plans to have large US oil companies enter Venezuela and get “oil flowing” will be hindered by lack of infrastructure that will require many years and heavy investment, analysts said. “There are still many questions that need to be answered about the state of the Venezuelan oil industry, but it is clear that it will take tens of billions of dollars to turn that industry around,” said Peter McNally, Global Head of Sector Analysts at Third Bridge, adding that it could take at least a decade of Western oil majors committing to the country.

A US embargo on all Venezuelan oil, meanwhile, remains in full effect, Trump said. He told reporters that the US military forces would remain in position until US demands had been fully met.

“The American armada remains poised in position, and the US retains all military options until United States demands have been fully met and fully satisfied,” he said.

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US Captures Venezuela’s Maduro, Trump Says US Will Run the Country

Smoke rises near Fort Tiuna during a full blackout, following explosions and loud noises, after U.S. President Donald Trump said the U.S. has struck Venezuela and captured its President Nicolas Maduro, in Caracas, Venezuela, January 3, 2026. REUTERS/Leonardo Fernandez Viloria

The US attacked Venezuela and deposed its long-serving President Nicolas Maduro in an overnight operation on Saturday, President Donald Trump said, in Washington’s most direct intervention in Latin America since the 1989 invasion of Panama.

“This was one of the most stunning, effective and powerful displays of American might and competence in American history,” Trump said at a press conference at his Mar-a-Lago resort in Florida, where he was flanked by senior officials, including Secretary of Defense Pete Hegseth and Secretary of State Marco Rubio.

Trump said Maduro was in custody and that American officials would take control of Venezuela.

“We’re going to run the country until such time as we can do a safe, proper and judicious transition,” he said. “We can’t take a chance that someone else takes over Venezuela who doesn’t have the interests of Venezuelans in mind.”

POTENTIAL POWER VACUUM

It is unclear how Trump plans to oversee Venezuela. Despite a dramatic overnight operation that knocked out electricity in part of Caracas and captured Maduro in or near one of his safe houses, US forces have no control over the country itself, and Maduro’s government appears to still be in charge.

The removal of Maduro, who led Venezuela with a heavy hand for more than 12 years, potentially opens a power vacuum in the Latin American country. Venezuelan Vice President Delcy Rodriguez — Maduro’s presumptive successor — is in Russia, four sources familiar with her movements said, stoking confusion about who is next in line to govern the South American country.

Russia’s foreign ministry said the report that Rodriguez is in Russia was “fake.”

Any serious destabilization in the nation of 28 million people threatens to hand Trump the type of quagmire that has marked US foreign policy for much of the 21st century, including the invasions of Afghanistan and Iraq – which were also premised on regime change.

The US has not made such a direct intervention in its backyard region since the invasion of Panama 37 years ago to depose military leader Manuel Noriega over allegations that he led a drug-running operation. The United States has leveled similar charges against Maduro, accusing him of running a “narco-state” and rigging the 2024 election.

Maduro, a 63-year-old former bus driver handpicked by the dying Hugo Chavez to succeed him in 2013, has denied those claims and said Washington was intent on taking control of his nation’s oil reserves, the largest in the world.

VENEZUELAN OFFICIALS DECRY U.S. ACTION

The streets of Venezuela appeared calm as the sun rose. Soldiers patrolled some parts and some small pro-Maduro crowds began gathering in Caracas.

Others, however, expressed relief.

“I’m happy, I doubted for a moment that it was happening because it’s like a movie,” said merchant Carolina Pimentel, 37, in the city of Maracay. “It’s all calm now but I feel like at any moment everyone will be out celebrating.”

Venezuelan officials condemned Saturday’s intervention. “In the unity of the people we will find the strength to resist and to triumph,” Defense Minister Vladimir Padrino said in a video message.

While various Latin American governments oppose Maduro and say he stole the 2024 vote, direct US action revives painful memories of past interventions and is generally strongly opposed by governments and populations in the region.

Trump’s action recalls the Monroe Doctrine, laid out in 1823 by President James Monroe, laying US claim to influence in the region, as well as the “gunboat diplomacy” seen under Theodore Roosevelt in the early 1900s.

Venezuelan allies Russia, Cuba and Iran were quick to condemn the strikes as a violation of sovereignty. Tehran urged the UN Security Council to stop the “unlawful aggression.”

Among major Latin American nations, Argentina’s President Javier Milei lauded Venezuela’s new “freedom” while Mexico condemned the intervention and Brazil’s President Luiz Inacio Lula da Silva said it crossed “an unacceptable line.”

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