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Raphael Mechoulam, Israel’s ‘father of cannabis research,’ dies at 92
(JTA) — In the early 1960s, a Bulgarian-born scientist named Raphael Mechoulam was caught carrying five kilograms of, as he called it, “superb, smuggled Lebanese hashish” on a bus from Tel Aviv to Rehovot. But he wasn’t planning on smoking the stuff.
Mechoulam was a fledgling researcher keen on exploring the science behind cannabis, a stigmatized plant whose specific medical properties were not yet known. Over the decades he became a pioneer in cannabis research, whose findings about the psychoactive substance helped ease its entry out of the counterculture and into the mainstream.
Mechoulam died in Israel at age 92; his death was announced Friday by American Friends of the Hebrew University, where Mechoulam helped form The Hebrew University Multidisciplinary Center for Cannabinoid Research in 2017.
“Most of the human and scientific knowledge about cannabis was accumulated thanks to Prof. Mechoulam,” Hebrew University President Asher Cohen said in a statement. “He paved the way for groundbreaking studies and initiated scientific cooperation between researchers around the world. Mechoulam was a sharp-minded and charismatic pioneer.”
As a professor in the Hebrew University School of Pharmacy, Mechoulam and his research team isolated THC, the psychoactive component of cannabis, as well as cannabidiol, or CBD, an active ingredient in cannabis with a range of medicinal benefits.
He also pioneered the study of the body’s own cannabinoid system, which produces chemicals similar to THC to help regulate appetite, manage pain and operate the immune system.
As Mechoulam discovered more about cannabis and its efficacy in easing symptoms of cancer, epilepsy and other diseases, he lamented that strict drug laws in the United States and elsewhere suppressed research and kept the derivatives of cannabis off the market.
“Medicinal cannabis has to follow medical lines of thought and development and modern medical routes” in order to be part of proper drugs, he told the New York Times in 2017. “Israel has more [clinical trials] than the United States at the moment, which is ridiculous.”
Mechoulam was a founding member of the International Association for Cannabinoid Medicines and the International Cannabinoid Research Society. In 1994, he was elected to be a member of the Israel Academy of Sciences and Humanities.
Mechoulam was born in Bulgaria in 1930 and immigrated in 1949 with his family to Israel, where he later studied chemistry. He received his PhD at the Weizmann Institute in Rehovot, writing a thesis on the chemistry of steroids. After postdoctoral studies at the Rockefeller Institute in New York, he joined the scientific staff of the Weizmann Institute.
Mechoulam became a full professor at Hebrew University in 1972 and was named the Lionel Jacobson Professor of Medicinal Chemistry in 1975, serving as the university’s rector from 1979-1982.
In 2022, the YIVO Institute for Jewish Research in New York City mounted its exhibition on Jewish contributions to the history of cannabis and highlighted the work of Mechoulam. “He’s worked on cannabis his entire life, and in the 1990s he and his colleagues discovered the endocannabinoid system, which regulates homeostasis — a significant discovery on how the human body deals with cannabinoids,” Eddy Portnoy, who curated the exhibit, told the Jewish Telegraphic Agency at the time. “I read an interview with him where he says that because he was in a small country, he would have to find a niche that other people weren’t working in.”
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The post Raphael Mechoulam, Israel’s ‘father of cannabis research,’ dies at 92 appeared first on Jewish Telegraphic Agency.
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Lindsey Graham urges Israel not to strike Iranian oil depots even as he says he helped make war happen
(JTA) — Sen. Lindsey Graham of South Carolina has called on Israel to rein in its attacks on Iranian oil infrastructure, marking a rare note of caution from a Republican lawmaker who has said he helped push the United States to join Israel in waging war against Iran.
In a post on X on Sunday, Graham praised Israel for its role in the war before adding that “there will be a day soon that the Iranian people will be in charge of their own fate, not the murderous ayatollah’s regime.”
“In that regard, please be cautious about what targets you select,” continued Graham. “Our goal is to liberate the Iranian people in a fashion that does not cripple their chance to start a new and better life when this regime collapses. The oil economy of Iran will be essential to that endeavor.”
Graham’s post linked to an Axios article that reported that the United States was alarmed by Israeli strikes over the weekend that targeted 30 Iranian fuel depots. On Monday, U.S. gas prices rose to their highest levels since 2024.
The warning from Graham, an ally of President Donald Trump and staunch supporter of Israel, comes days after the Republican hawk told the Wall Street Journal that he had played a key role in urging Trump to strike Iran.
Prior to the joint U.S.-Israeli strikes on Iran, Graham made several trips to Israel where he met with members of the Mossad, Israel’s intelligence agency, as well as Israeli Prime Minister Benjamin Netanyahu whom he said he coached on how to lobby Trump to strike Iran.
“They’ll tell me things our own government won’t tell me,” Graham told the newspaper.
On Monday, Graham also directed his criticism at Saudi Arabia’s decision to stay on the sidelines of the campaign against Iran.
“It is my understanding the Kingdom refuses to use their capable military as a part of an effort to end the barbaric and terrorist Iranian regime who has terrorized the region and killed 7 Americans,” wrote Graham in a post on X Monday. “Question – why should America do a defense agreement with a country like the Kingdom of Saudi Arabia that is unwilling to join a fight of mutual interest?”
The post Lindsey Graham urges Israel not to strike Iranian oil depots even as he says he helped make war happen appeared first on The Forward.
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Belgian officials investigating synagogue explosion as possible act of terrorism
(JTA) — Belgian officials are investigating an explosion in front of a synagogue in Liège early Monday as a possible act of terrorism.
The explosion, which took place at 4 a.m., damaged the door of the historic neo-Romanesque synagogue and blew out the windows of multiple buildings across the street. No injuries were reported.
A range of Belgian politicians, including the prime minister and the mayor of Liège, characterized the explosion as act of antisemitism.
“Antisemitism is an attack on our values and our society, and we must fight it unequivocally,” Prime Minister Bart de Wever said in a statement. “We stand in solidarity with the Jewish community in Liege and across the country.”
The explosion comes amid a surge of concern about possible attacks by agents associated with the Iranian regime, against which the United States and Israel launched a war last week. Iran has a long record of supporting attacks on Jewish targets abroad, including two bombings in the 1990s in Argentina that killed more than 100 people at the Israeli embassy and a Jewish community center. Now, with Iran being pummeled at home, watchdogs are warning that it might lash out through its Iranian Islamic Revolutionary Guard Corps Quds Force, responsible for attacks abroad.
Azerbaijan said Friday that it had foiled multiple terror attacks planned by Iranian agents on Jewish sites. In London, four men were arrested last week for allegedly spying on the Jewish community for Iran, with the intent of planning attacks against the community. And a string of shootings at synagogues in Toronto has ignited concern in Canada, too.
Iranian agents have taken aim at non-Jewish targets, too. On Friday, a Pakistani man who prosecutors said had been directed by Iran’s IRGC was convicted of plotting to assassinate President Donald Trump.
The attack in Liège, in the primarily French-speaking Wallonia province, comes amid a range of recent developments that have unsettled Belgian Jews, who number approximately 30,000. They include antisemitic carnival caricatures in the city of Aalst; a ban on ritual slaughter preventing the local production of kosher meat; and an ongoing row between U.S. and Belgian officials over Jewish circumcision practices. The attack also follows a 2014 shooting in which a gunman associated with the Islamic State, a rival to Iran’s Islamic Republic, shot four people to death at the Jewish Museum in Brussels.
A spokesperson for the Liège police described the effects to the area as “only material damage” to the 1899 building. Rabbi Joshua Nejman told local media that he was hoping that security footage would reveal the perpetrator.
“I’m going to try to calm my heart, because it is beating faster and faster this morning,” said Nejman, who said he had been at the synagogue for 25 years.
“Liege is home to a very small but vibrant Jewish community where I personally grew up,” Eitan Bergman, vice president of the Coordinating Committee of Jewish Organisations in Belgium, told Reuters. “Today, the feelings among our community members are a mixture of sadness, worry and profound shock.”
Liege’s mayor, Willy Demeyer, praised the synagogue community to RBTF, Belgium’s French-language national broadcaster. He added, “We cannot allow foreign conflicts to be imported into our city.”
The post Belgian officials investigating synagogue explosion as possible act of terrorism appeared first on The Forward.
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The Top 100 People Positively Influencing Jewish Life, 2025
In honor of The Algemeiner‘s 12th annual gala, we are proud to present our “J100” list — 100 individuals who have positively influenced Jewish life over the past year.