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Raphael Mechoulam, Israel’s ‘father of cannabis research,’ dies at 92
(JTA) — In the early 1960s, a Bulgarian-born scientist named Raphael Mechoulam was caught carrying five kilograms of, as he called it, “superb, smuggled Lebanese hashish” on a bus from Tel Aviv to Rehovot. But he wasn’t planning on smoking the stuff.
Mechoulam was a fledgling researcher keen on exploring the science behind cannabis, a stigmatized plant whose specific medical properties were not yet known. Over the decades he became a pioneer in cannabis research, whose findings about the psychoactive substance helped ease its entry out of the counterculture and into the mainstream.
Mechoulam died in Israel at age 92; his death was announced Friday by American Friends of the Hebrew University, where Mechoulam helped form The Hebrew University Multidisciplinary Center for Cannabinoid Research in 2017.
“Most of the human and scientific knowledge about cannabis was accumulated thanks to Prof. Mechoulam,” Hebrew University President Asher Cohen said in a statement. “He paved the way for groundbreaking studies and initiated scientific cooperation between researchers around the world. Mechoulam was a sharp-minded and charismatic pioneer.”
As a professor in the Hebrew University School of Pharmacy, Mechoulam and his research team isolated THC, the psychoactive component of cannabis, as well as cannabidiol, or CBD, an active ingredient in cannabis with a range of medicinal benefits.
He also pioneered the study of the body’s own cannabinoid system, which produces chemicals similar to THC to help regulate appetite, manage pain and operate the immune system.
As Mechoulam discovered more about cannabis and its efficacy in easing symptoms of cancer, epilepsy and other diseases, he lamented that strict drug laws in the United States and elsewhere suppressed research and kept the derivatives of cannabis off the market.
“Medicinal cannabis has to follow medical lines of thought and development and modern medical routes” in order to be part of proper drugs, he told the New York Times in 2017. “Israel has more [clinical trials] than the United States at the moment, which is ridiculous.”
Mechoulam was a founding member of the International Association for Cannabinoid Medicines and the International Cannabinoid Research Society. In 1994, he was elected to be a member of the Israel Academy of Sciences and Humanities.
Mechoulam was born in Bulgaria in 1930 and immigrated in 1949 with his family to Israel, where he later studied chemistry. He received his PhD at the Weizmann Institute in Rehovot, writing a thesis on the chemistry of steroids. After postdoctoral studies at the Rockefeller Institute in New York, he joined the scientific staff of the Weizmann Institute.
Mechoulam became a full professor at Hebrew University in 1972 and was named the Lionel Jacobson Professor of Medicinal Chemistry in 1975, serving as the university’s rector from 1979-1982.
In 2022, the YIVO Institute for Jewish Research in New York City mounted its exhibition on Jewish contributions to the history of cannabis and highlighted the work of Mechoulam. “He’s worked on cannabis his entire life, and in the 1990s he and his colleagues discovered the endocannabinoid system, which regulates homeostasis — a significant discovery on how the human body deals with cannabinoids,” Eddy Portnoy, who curated the exhibit, told the Jewish Telegraphic Agency at the time. “I read an interview with him where he says that because he was in a small country, he would have to find a niche that other people weren’t working in.”
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Israeli Artist Forced to Close Mexico City Exhibit for ‘Safety Reasons’ After Antisemitic Harassment, Vandalism
Pro-Palestinian protesters and vandals hold a flag during a demonstration against Amir Fattal, an openly Zionist Israeli graphic artist. They later spray-painted the facade of the private KÖNIG GALERIE gallery, where he was exhibiting some of his AI-generated works. Photo: Gerardo Vieyra / SOPA Images via Reuters Connect
An Israeli artist based in Berlin was forced to close his solo exhibition at a Mexico City gallery a week earlier than planned following continued antisemitic harassment, a protest at his exhibit, and vandalism of the gallery.
Artist and curator Amir Fattal shared the news on Instagram about the closing of his exhibit, “I’m Just Here For The Pool,” at the König contemporary art gallery. The show opened on Feb. 3 and was expected to close on April 1, according to the gallery.
On March 26, pro-Palestinian activists spray-painted antisemitic and anti-Israel messages and symbols across the outer walls of the König gallery. Swastikas, Star of Davids, the word “Nazi,” and more offensive messages were spray-painted along with the number “666.” The number is used by the Aryan Brotherhood, a white supremacist group, and it signifies the “number of the beast,” according to the Anti-Defamation League. On the door of the gallery, a vandal carved a swastika and the phrase “acqui hay terroristas,” which translates in English to “here there are terrorists.” The same phrase was written in chalk on the street in front of the gallery, according to photos shared by Reuters.
On March 21, during a guided tour of the gallery, roughly 15 demonstrators gathered outside, chanted against Fattal, and called him “a murderer” and “a Mossad agent,” according to Artnet.
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Israeli Forces to Expand Control in Southern Lebanon as Defense Chief Outlines Long-Term Security Plans
Smoke rises after an Israeli strike, amid escalating hostilities between Israel and Hezbollah, as the US-Israeli conflict with Iran continues, in southern Lebanon, March 28, 2026. Photo: REUTERS/Stringer
Israeli Defense Minister Israel Katz announced on Tuesday that the Israel Defense Forces (IDF) will maintain security control over territory in southern Lebanon up to the Litani River even after active ground operations against Hezbollah conclude, signaling plans for a sustained Israeli security presence along the northern front.
During a press briefing, Katz pointed to a shift beyond limited cross-border raids, outlining plans for a long-term security presence and the creation of a buffer zone as part of a broader effort to reshape the security landscape in Lebanon.
Under this new plan, the IDF will move to dismantle terrorist infrastructure in border villages using operational methods similar to those employed in the Gaza Strip against Hamas, aiming to permanently eliminate the threat of cross-border raids and anti-tank fire targeting Israeli frontline communities.
“The return of more than 600,000 southern Lebanese residents who fled north of the Litani River will remain completely prohibited until the security of Israel’s northern residents is guaranteed,” the Israeli defense chief said.
Katz also announced the IDF plans to establish a new defensive line inside Lebanese territory once the ground campaign concludes.
“The IDF will maintain security control over the entire area up to the Litani River, including all bridges, while fully neutralizing Radwan’s forces and destroying their weapons,” he said, referring to Hezbollah’s elite units.
“We are determined to separate Lebanon from Iran’s influence, to uproot the snake’s teeth, and eliminate Hezbollah’s threat capability,” Katz continued. “The situation in Lebanon will change once and for all — we will enforce security just as we do in Syria and Gaza.”
During a cabinet meeting on Tuesday, Israeli Prime Minister Benjamin Netanyahu outlined a tougher operational approach to the campaign in Lebanon, emphasizing shifts in battlefield tactics following the heavy toll the fighting has taken.
“I have ordered our soldiers to avoid entering buildings whenever possible, using mechanical engineering equipment and heavy weapons instead,” Netanyahu said, explaining that the goal is to “minimize casualties” and to safeguard soldiers on the ground.
With prospects of potential ceasefire negotiations with Iran to end the ongoing war still uncertain, Netanyahu said Israel is shaping a new security reality along its northern border and will act independently of any agreement possibly reached with Tehran.
“Even if an agreement is reached with Iran, a ceasefire in Lebanon cannot be imposed on us — that must be Israel’s own independent decision,” the Israeli leader said.
The Iranian regime backs and ultimately commands Hezbollah, having formed the Lebanese terrorist group in the 1980s and, since then, providing significant amounts of weapons, funding, and training.
Last week, Hezbollah Secretary General Naim Qassem warned that negotiating with Israel while under fire would amount to forced surrender, adding that his fighters are prepared to continue operations “without limits.”
With a ground maneuver underway to expand a defensive zone in southern Lebanon, the IDF says it has eliminated over 850 Hezbollah terrorists since fighting began earlier this month, while continuing to dismantle the group’s command and weapons infrastructure.
Israel has intensified strikes targeting Hezbollah, particularly south of the Litani River, where the group’s operatives have historically been most active against the Jewish state. Hezbollah opened fire on Israel earlier this month, just a few days after the US and Israel launched their joint military campaign against Iran.
Israel has long demanded that Hezbollah be barred from carrying out activities south of the Litani, located roughly 15 miles from the Israeli border.
Although the overall number of attacks has decreased, Hezbollah continues to launch significant strikes against civilian areas while maintaining sustained operations targeting IDF forces in southern Lebanon.
In just the first month of the conflict, Israeli officials report that Hezbollah has carried out more than 900 coordinated attacks, marking a sharp increase in cross-border activity and a broader expansion of its operations across the region.
On Sunday, Israeli forces intercepted a Hezbollah a terrorist cell disguised as paramedics who tried to transport weapons in an ambulance.
For years, Hezbollah has embedded command posts, weapons depots, snipers, and troops within Shiite villages, situating them in the heart of civilian centers near schools, hospitals, mosques, and main roads to turn entire communities into battlefields.
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Newest Members of the IDF’s Ultra-Orthodox Hasmonean Brigade Get Their Berets
Illustrative: Members of the Hasmonean Brigade during their beret ceremony at the Western Wall on Aug. 6, 2024. Photo: Screenshot
The third set of soldiers in the Hasmonean Brigade, the Israel Defense Force’s first ultra-Orthodox brigade, completed eight months of training earlier this month and received their dark blue berets at the end of a beret march of approximately 40 kilometers, according to the Israeli news outlet Walla.
The troops will join the regular forces of the Hasmonean Brigade, which was established in 2024 and has participated in military operations in Syria, the West Bank, the Gaza Strip, and southern Lebanon. Members of the brigade live an ultra-Orthodox lifestyle, and their blue berets reportedly symbolize the sky. The brigade is named after the Hasmonean Jewish dynasty that ruled Judea, and liberated Jerusalem and the Temple from oppressive Greek rule.
In February, members of the Hasmonean Brigade’s Yonatan Battalion completed its first-ever battalion-level exercise in the Golan Heights area, “marking the conclusion of the battalion’s operational certification process and its preparation for operational activity,” according to the military. During the exercise, the soldiers were trained in combat in open terrain, targeted operations, and urban warfare scenarios. It took place mere weeks after the start of the Israel-Iran war, also known as Operation Roaring Lion.
“You can be ultra-Orthodox and be a combat soldier – you are making history,” Commander of the Ground Forces, Major General Nadav Lotan, said at the time. “The Hasmonean Brigade continues to establish itself as a combat brigade within the ground forces. This exercise, along with the establishment of the battalions, marks another significant step forward. I am proud of you – the brigade’s troops and commanders. You operate at a high operational standard while preserving your unique identity.”