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Raphael Mechoulam, Israel’s ‘father of cannabis research,’ dies at 92
(JTA) — In the early 1960s, a Bulgarian-born scientist named Raphael Mechoulam was caught carrying five kilograms of, as he called it, “superb, smuggled Lebanese hashish” on a bus from Tel Aviv to Rehovot. But he wasn’t planning on smoking the stuff.
Mechoulam was a fledgling researcher keen on exploring the science behind cannabis, a stigmatized plant whose specific medical properties were not yet known. Over the decades he became a pioneer in cannabis research, whose findings about the psychoactive substance helped ease its entry out of the counterculture and into the mainstream.
Mechoulam died in Israel at age 92; his death was announced Friday by American Friends of the Hebrew University, where Mechoulam helped form The Hebrew University Multidisciplinary Center for Cannabinoid Research in 2017.
“Most of the human and scientific knowledge about cannabis was accumulated thanks to Prof. Mechoulam,” Hebrew University President Asher Cohen said in a statement. “He paved the way for groundbreaking studies and initiated scientific cooperation between researchers around the world. Mechoulam was a sharp-minded and charismatic pioneer.”
As a professor in the Hebrew University School of Pharmacy, Mechoulam and his research team isolated THC, the psychoactive component of cannabis, as well as cannabidiol, or CBD, an active ingredient in cannabis with a range of medicinal benefits.
He also pioneered the study of the body’s own cannabinoid system, which produces chemicals similar to THC to help regulate appetite, manage pain and operate the immune system.
As Mechoulam discovered more about cannabis and its efficacy in easing symptoms of cancer, epilepsy and other diseases, he lamented that strict drug laws in the United States and elsewhere suppressed research and kept the derivatives of cannabis off the market.
“Medicinal cannabis has to follow medical lines of thought and development and modern medical routes” in order to be part of proper drugs, he told the New York Times in 2017. “Israel has more [clinical trials] than the United States at the moment, which is ridiculous.”
Mechoulam was a founding member of the International Association for Cannabinoid Medicines and the International Cannabinoid Research Society. In 1994, he was elected to be a member of the Israel Academy of Sciences and Humanities.
Mechoulam was born in Bulgaria in 1930 and immigrated in 1949 with his family to Israel, where he later studied chemistry. He received his PhD at the Weizmann Institute in Rehovot, writing a thesis on the chemistry of steroids. After postdoctoral studies at the Rockefeller Institute in New York, he joined the scientific staff of the Weizmann Institute.
Mechoulam became a full professor at Hebrew University in 1972 and was named the Lionel Jacobson Professor of Medicinal Chemistry in 1975, serving as the university’s rector from 1979-1982.
In 2022, the YIVO Institute for Jewish Research in New York City mounted its exhibition on Jewish contributions to the history of cannabis and highlighted the work of Mechoulam. “He’s worked on cannabis his entire life, and in the 1990s he and his colleagues discovered the endocannabinoid system, which regulates homeostasis — a significant discovery on how the human body deals with cannabinoids,” Eddy Portnoy, who curated the exhibit, told the Jewish Telegraphic Agency at the time. “I read an interview with him where he says that because he was in a small country, he would have to find a niche that other people weren’t working in.”
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U.S. Senate candidate from Michigan calls Israeli government ‘evil’ like Hamas
Abdul El-Sayed, a U.S. Senate candidate from Michigan, said in an interview aired Sunday that the Israeli government is as “evil” as Hamas, sharpening his criticism of Israel in the closely-watched Democratic primary.
“Killing tens of thousands of people makes you pretty damn evil,” El-Sayed told CNN congressional reporter Manu Raja on the network’s Inside Politics program. “It’s not how evil is this one versus that one — Hamas: Evil, Israeli government: Evil. We can say both.”
El-Sayed, 41, is a physician and the son of Egyptian immigrants. He is seeking to channel the energy of the 2024 Uncommitted movement, which protested the Biden administration’s support for Israel in the war against Hamas in Gaza. He is also hoping to build on the surprise success of the New York City mayoral campaign of Zohran Mamdani in taking on the Democratic establishment.
He is locked in a dead heat with state Sen. Mallory McMorrow and Rep. Haley Stevens. The primary is set for Aug. 4.
Earlier this month, El-Sayed faced backlash for appearing alongside streamer Hasan Piker, who has been accused of antisemitic rhetoric — including saying that Hamas “is a thousand times better” than Israel. McMorrow, who is married to a Jewish man, and Stevens, who is closely aligned with AIPAC, have both criticized El-Sayed.
In the CNN interview, El-Sayed defended his decision to campaign with Piker, framing it as an effort to reach voters who feel alienated from traditional politics. “My understanding of America is, it’s a place where we have freedom of speech,” he said.
#MISen Abdul El-Sayed on CNN Inside Politics: @mkraju: You said Israeli government is evil. Do you think they’re just as evil as Hamas?
El-Sayed: “Yes, killing tens of thousands of people makes you pretty damn evil. It’s not about how evil one is versus the other. Hamas —… pic.twitter.com/4GfJ5oCtqR
— Jacob N. Kornbluh (@jacobkornbluh) April 19, 2026
The Michigan Senate race is shaping up as one of the starkest tests of the Democratic coalition and how the party navigates policy towards Israel in Congress amid the wars in Gaza and Iran. The state is home to the largest concentration of Arab Americans in the United States.
Last week, 40 Senate Democrats voted to block $295 million for the transfer of bulldozers, used by the Israeli military to demolish homes in the West Bank and Gaza; 36 of them also supported a measure to block the sale of 1,000-pound bombs to the Jewish state. It shattered a previous high of 27 Democrats who backed a similar pair of resolutions of disapproval to block some weapons transfers last year.
Sen. Elissa Slotkin of Michigan, who is Jewish, was among those who voted for the measures. In remarks as they announced their votes, Democrats highlighted their opposition to the Israeli government’s policies in the occupied West Bank, the humanitarian situation in Gaza and the war with Iran.
The post U.S. Senate candidate from Michigan calls Israeli government ‘evil’ like Hamas appeared first on The Forward.
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NYC Mayor Mamdani Unveils Major Tax Hike on Unoccupied Luxury Real Estate
New York City Mayor Zohran Mamdani holds a press conference at the New York City Office of Emergency Management, as a major winter storm spreads across a large swath of the United States, in Brooklyn, New York City, US, Jan. 25, 2026. Photo: REUTERS/Bing Guan
i24 News – NYC Mayor Zohran Mamdani has officially introduced a controversial new tax targeting secondary residences valued at over $5 million.
The measure, designed to tap into the city’s vast concentration of unoccupied luxury wealth, is projected to generate roughly $500 million annually for the municipal budget.
“This tax is specifically aimed at the ultra-rich,” Mamdani stated, highlighting high-profile examples such as Ken Griffin’s $238 million Midtown penthouse and Alexander Varshavsky’s $20.5 million Columbus Circle residence.
While the city has yet to finalize specific evaluation criteria or the methods for distinguishing primary from secondary homes, the proposal has already become a flashpoint for economic debate.
The move has drawn sharp condemnation from billionaire investor Bill Ackman, who argued that the policy is fundamentally flawed.
Ackman contended that owners of luxury secondary residences contribute significant capital to the local economy without utilizing costly municipal services. He warned that the tax would likely trigger a corporate and high-net-worth exodus to low-tax jurisdictions like Miami, ultimately harming the city’s tax base.
President Donald Trump also entered the fray, denouncing the policy as “totally misguided” and claiming it is “destroying New York.” Trump, whose own extensive real estate holdings in the city could be impacted, argued that such taxation serves only to drive away the international investors who fuel New York’s development.
Implementation remains a significant question mark, as the tax could potentially affect nearly 13,000 property owners, including major figures like Jeff Bezos. Financial analysts point out that many of the city’s most expensive apartments are held through complex offshore structures and shell companies, making the identification and appraisal of these properties an immense administrative challenge for the city.
As the debate intensifies, the Mamdani administration faces a difficult path ahead in balancing its “tax the rich” mandate with the practical realities of New York’s competitive global real estate market.
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Iran Rebuffs Trump Announcement of New Peace Talks, State News Agency Reports
Iran rejected new peace talks with the United States, its state news agency reported on Sunday, hours after US President Donald Trump said he was sending envoys for talks in Pakistan and would launch new strikes on Iran unless it accepts his terms.
Trump posted on Truth Social that his envoys would arrive in Pakistan on Monday evening for negotiations, a timetable that would leave only a day for talks to make progress before a two-week ceasefire ends.
“We’re offering a very fair and reasonable DEAL, and I hope they take it because, if they don’t, the United States is going to knock out every single Power Plant, and every single Bridge, in Iran,” he wrote. “NO MORE MR. NICE GUY!”
Iran’s official IRNA news agency cited no specific source in its report that Iran had rejected the talks.
“Iran stated that its absence from the second round of talks stems from what it called Washington’s excessive demands, unrealistic expectations, constant shifts in stance, repeated contradictions, and the ongoing naval blockade, which it considers a breach of the ceasefire,” IRNA wrote.
The White House did not immediately respond to a request for comment on Iran’s rejection of the talks.
Earlier, a White House official said the US delegation would be headed by Vice President JD Vance, who led the war’s first peace talks a week ago, and also include Trump’s envoy Steven Witkoff and son-in-law Jared Kushner. Trump had initially told ABC News and MS Now that Vance would not go.