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Raphael Mechoulam, Israel’s ‘father of cannabis research,’ dies at 92
(JTA) — In the early 1960s, a Bulgarian-born scientist named Raphael Mechoulam was caught carrying five kilograms of, as he called it, “superb, smuggled Lebanese hashish” on a bus from Tel Aviv to Rehovot. But he wasn’t planning on smoking the stuff.
Mechoulam was a fledgling researcher keen on exploring the science behind cannabis, a stigmatized plant whose specific medical properties were not yet known. Over the decades he became a pioneer in cannabis research, whose findings about the psychoactive substance helped ease its entry out of the counterculture and into the mainstream.
Mechoulam died in Israel at age 92; his death was announced Friday by American Friends of the Hebrew University, where Mechoulam helped form The Hebrew University Multidisciplinary Center for Cannabinoid Research in 2017.
“Most of the human and scientific knowledge about cannabis was accumulated thanks to Prof. Mechoulam,” Hebrew University President Asher Cohen said in a statement. “He paved the way for groundbreaking studies and initiated scientific cooperation between researchers around the world. Mechoulam was a sharp-minded and charismatic pioneer.”
As a professor in the Hebrew University School of Pharmacy, Mechoulam and his research team isolated THC, the psychoactive component of cannabis, as well as cannabidiol, or CBD, an active ingredient in cannabis with a range of medicinal benefits.
He also pioneered the study of the body’s own cannabinoid system, which produces chemicals similar to THC to help regulate appetite, manage pain and operate the immune system.
As Mechoulam discovered more about cannabis and its efficacy in easing symptoms of cancer, epilepsy and other diseases, he lamented that strict drug laws in the United States and elsewhere suppressed research and kept the derivatives of cannabis off the market.
“Medicinal cannabis has to follow medical lines of thought and development and modern medical routes” in order to be part of proper drugs, he told the New York Times in 2017. “Israel has more [clinical trials] than the United States at the moment, which is ridiculous.”
Mechoulam was a founding member of the International Association for Cannabinoid Medicines and the International Cannabinoid Research Society. In 1994, he was elected to be a member of the Israel Academy of Sciences and Humanities.
Mechoulam was born in Bulgaria in 1930 and immigrated in 1949 with his family to Israel, where he later studied chemistry. He received his PhD at the Weizmann Institute in Rehovot, writing a thesis on the chemistry of steroids. After postdoctoral studies at the Rockefeller Institute in New York, he joined the scientific staff of the Weizmann Institute.
Mechoulam became a full professor at Hebrew University in 1972 and was named the Lionel Jacobson Professor of Medicinal Chemistry in 1975, serving as the university’s rector from 1979-1982.
In 2022, the YIVO Institute for Jewish Research in New York City mounted its exhibition on Jewish contributions to the history of cannabis and highlighted the work of Mechoulam. “He’s worked on cannabis his entire life, and in the 1990s he and his colleagues discovered the endocannabinoid system, which regulates homeostasis — a significant discovery on how the human body deals with cannabinoids,” Eddy Portnoy, who curated the exhibit, told the Jewish Telegraphic Agency at the time. “I read an interview with him where he says that because he was in a small country, he would have to find a niche that other people weren’t working in.”
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Pope Leo Says Those Who Wage War Are Thieves Stealing Away Our Peaceful Future
Pope Leo XIV looks on as he meets with Catholic religious education teachers attending a national meeting organised by the Italian Bishops’ Conference (CEI), in the Paul VI Hall at the Vatican, April 25, 2026. Photo: REUTERS/Yara Nardi
Pope Leo on Sunday described those who wage wars and appropriate the earth’s resources as thieves who rob the world of a peaceful future, issuing a warning about the use of nuclear power on the anniversary of the Chernobyl reactor accident.
Ukraine is commemorating the 40th anniversary of the world’s worst nuclear disaster on Sunday amid lingering fears that Russia’s four-year-old war could spark a repeat of the tragedy.
In his weekly address after the Angelus prayer, the Pontiff said the Chernobyl accident had left a mark on humankind’s collective conscience.
“It remains a warning over the use of ever more powerful technologies,” the Pope, who has just returned from a 10-day tour across four African nations, said.
“I hope that at all decision-making levels, wisdom and responsibility always prevail, so that atomic power can always be used to support life and peace,” he added.
Commenting on the Gospel of the day, which contained the metaphor of a sheep thief, Pope Leo said thieves came under many appearances, listing as examples “superficial lifestyles driven by consumerism,” prejudices and wrong ideas.
“And let’s not forget also those thieves who, by plundering the earth’s resources, by fighting bloody wars or feeding evil in whichever form, are simply taking away from all of us the chance of a future of peace and serenity,” he added.
Leo, the first US pontiff, has attracted the ire of President Donald Trump after becoming more outspoken against war and despotism.
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UK’s Starmer and Trump Discuss ‘Urgent Need’ to Restore Shipping in Strait of Hormuz
British Prime Minister Keir Starmer and US President Donald Trump (not pictured) hold a bilateral meeting at Trump Turnberry golf course in Turnberry, Scotland, Britain, July 28, 2025. Photo: REUTERS/Evelyn Hockstein
British Prime Minister Keir Starmer and US President Donald Trump discussed the urgent need to get shipping moving again in the Strait of Hormuz during a call on Sunday, a Downing Street spokesperson said.
“The leaders discussed the urgent need to get shipping moving again in the Strait of Hormuz, given the severe consequences for the global economy and cost of living for people in the UK and globally,” the spokesperson for Starmer’s office said in a statement.
“The prime minister shared the latest progress on his joint initiative with President (Emmanuel) Macron to restore freedom of navigation,” the spokesperson added.
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Palestinian Leader’s Loyalists Win Local Elections, Including Some Seats in Gaza
A Palestinian man votes during the municipal election at a polling station in Deir al-Balah, central Gaza Strip April 25, 2026. Photo: REUTERS/Mahmoud Issa
Loyalists of President Mahmoud Abbas won most races in Palestinian municipal elections, election officials said on Sunday, in a vote that for the first time in nearly two decades included a city in the Gaza Strip run by rival Hamas.
Saturday’s ballot marked the first elections of any kind in Gaza since 2006 and the first Palestinian polls since the Gaza war began more than two years ago with Hamas’ cross‑border attack on southern Israel.
Abbas’ West Bank–based Palestinian Authority (PA) said the inclusion of the Gaza city Deir al‑Balah, which suffered less damage than other areas of the coastal territory during the war, was intended to show that Gaza was an inseparable part of a future Palestinian state.
The elections, in which voter turnout was low, had been held “at a highly sensitive moment amid complex challenges and exceptional circumstances,” Palestinian Prime Minister Mohammad Mustafa said as results were announced on Sunday.
But they represented “an important first step in a broader national process aimed at strengthening democratic life … and ultimately achieving the unity of the homeland,” he said.
POSSIBLE INDICATOR OF HAMAS SUPPORT
Hamas, which ousted the PA from Gaza in 2007, did not formally nominate candidates in Gaza and boycotted the race in the Israeli-occupied West Bank, where Fatah’s victory was widely expected.
But some candidates on one of the Deir al-Balah lists were widely seen by residents and analysts as aligned with the movement, making the vote a potential indicator of support for the Islamist group.
Preliminary results showed that the list, known as Deir al‑Balah Brings Us Together, won only two of the 15 seats contested in Gaza.
The Nahdat Deir al‑Balah list, backed by Abbas’ Fatah party and the Western-backed PA, secured six seats. The remaining seats were won by two other Gaza-based groups, Future of Deir al‑Balah and Peace and Building, not affiliated with either faction.
Abbas loyalists swept the election in the West Bank, running unchallenged in many seats.
Fatah spokesperson Abdul Fattah Dawla noted that turnout was close to that for the last municipal elections in the West Bank, in 2022, praising voters for participating despite ongoing violence by Israel.
“By electing figures linked to Fatah, voters appear to be seeking unrestricted international support for municipal governance and a gradual political shift that could extend beyond the local level,” said Palestinian political analyst Reham Ouda.
The recent war has left much of Gaza reduced to rubble, with many residents displaced and focused on survival. Israel has continued conducting strikes despite an October ceasefire.
In Gaza, voter turnout reached just 23 percent, while in the West Bank it was 56 percent, according to Chairman of the Central Elections Commission Rami al‑Hamdallah.
Al‑Hamdallah said some of the ballot boxes and voting equipment did not make it into the enclave because of Israeli security restrictions, though those challenges were overcome.
Hamas’ Gaza spokesperson, Hazem Qassem, downplayed the significance of the election results, saying that they had no impact on wider national issues.