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Famed biographer Walter Isaacson’s latest book examines how “Crispr” tecnnology developed and how it’s changing our world

Cover of “The Codebreaker”
with Dr. Jennifer Doudna
right: author Walter Isaacson

By MARTIN ZEILIG During the recent rebroadcast of an interview on CBC Radio’s science show, Quirks & Quarks, Dr. Jennifer Doudna told how it “was a real shock” when she received an early morning telephone call notifying her of having been co-awarded the 2020 Nobel Prize in Chemistry.
She’s a humble person. But, she shouldn’t have been so surprised.

Doudna, a professor of molecular and cell biology at University of California, Berkeley, and her collaborator, a French professor and researcher in microbiology, genetics, and biochemistry at the Max Planck Institute in Berlin, Germany, were awarded the prize for the development of the CRISPR-Cas9 genome editing technique.
This meticulously researched book by author Walter Isaacson takes a reader into the quest by Doudna and Charpentier that eventually led to their breakthrough discovery. We see Doudna as a liberal minded and generous person, as well as a brilliant and driven research scientist.

Walter Isaacson, a professor of history at Tulane University, has been CEO of the Aspen Institute, chair of CNN, and an editor at Time Magazine. He is the author of “Leonardo da Vinci”, “The Innovators”, “Steve Jobs”, “Einstein: His Life and Universe”, “Benjamin Franklin: An American Life”, and “Kissinger: A Biography”, also the coauthor of “The Wise Men: Six Friends and the World They Made”.

The essence of CRISPR (an acronym for clustered regularly interspaced short palindromic repeats) is simple: It’s a way of finding a specific bit of DNA inside a cell.

“CRISPR technology also has the potential to transform medicine, enabling us to not only treat but also prevent many diseases. We may even decide to use it to change the genomes of our children. An attempt to do this in China has been condemned as premature and unethical, but some think it could benefit children in the future, notes online information. After that, the next step in CRISPR gene editing is usually to alter that piece of DNA. However, CRISPR has also been adapted to do other things too, such as turning genes on or off without altering their sequence.
“There were ways to edit the genomes of some plants and animals before the CRISPR method was unveiled in 2012 but it took years and cost hundreds of thousands of dollars,” says the science site.
“CRISPR has made it cheap and easy.

“CRISPR is already widely used for scientific research, and in the not too distant future many of the plants and animals in our farms, gardens or homes may have been altered with CRISPR. In fact, some people already are eating CRISPRed food.
“CRISPR is being used for all kinds of other purposes too, from fingerprinting cells and logging what happens inside them to directing evolution and treating gene drives.
“The key to CRISPR is the many flavours of “Cas” proteins found in bacteria, where they help defend against viruses. The Cas9 protein is the most widely used by scientists. This protein can easily be programmed to find and bind to almost any desired target sequence, simply by giving it a piece of RNA to guide it in its search.”

Isaacson describes how a young Doudna came home one day from grade school to find that her father had left a paperback issue of the book, “The Double Helix”, by James Watson, on her bed. That classic and compelling story about Watson and his collaborator Frances Crick’s (1916-2004) race to discover the structure of DNA delighted Doudna.
Years later, Watson praised Doudna for her role in, as the author writes, “the most important biological advance” since his codiscovery of the structure of DNA.

There are many other prominent and not so well known names, at least to the non-science community, referenced in this superb story.
“The inner workings of molecules may remain, for most people, as mysterious as those of microchips, but at least all of us will be a bit more aware of the beauty and power of both,” the author writes.

“By honoring CRISPR, a virus-fighting system found in nature, in the midst of a virus pandemic, the Nobel committee reminded us how curiosity-driven basic research can end up having very practical applications. CRISPR and COVID are speeding our entry into a life-science era. Molecules are becoming the new microchips.”
This book helps us to understand that brave new world.

“The Code Breaker: Jennifer Doudna, Gene Editing, and the Future of the Human Race”
by Walter Isaacson
(Simon & Schuster 536 pg. $40.00)

 

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Features

Securing Your Account on PHBingo Login (GameZone)

The rising popularity of online casino platforms like GameZone has attracted many players eager to indulge in their favorite bingo games. As the number of users grows, so does the need for account security. Protecting personal data, playing progress, and account wallets has become vital due to the increase in online threats. Learning effective security techniques for PHBingo Login (GameZone) is essential for players, ensuring both safety and uninterrupted gameplay.

GameZone, a platform that features traditional and modern bingo games, stores sensitive information about user details, progress, and financial data. Without proper precautions, accounts may fall victim to unauthorized access, leading to loss of control, misuse of credentials, and exposure to significant risks. Following preventative measures will allow players to enjoy their favorite games worry-free.

Risks of Unauthorized Access in Online Bingo Play

Players using GameZone or similar platforms need to consider the potential consequences of compromised accounts. The inability to access an account, unauthorized transactions, and losing virtual credits are common issues resulting from poor security. Personal data, such as email addresses or payment information, is also at risk once hackers gain access.

While online casino platforms offer built-in security mechanisms, users carry the responsibility of implementing their own account protection solutions. Taking proactive steps, such as using strong passwords and enabling additional security layers, greatly reduces exposure to risks.

Steps to Secure Your PHBingo Account

1. Set a Strong, Unique Password

Having an easily guessed password, like “123456” or a birthdate, leaves accounts highly vulnerable. Strong passwords are critical for better security and protecting login details.

Strong password elements to consider:

  • A combination of uppercase and lowercase letters
  • Numbers and symbols
  • A length of at least 8–12 characters

Using different passwords for each account ensures that other platforms won’t be compromised if one is hacked. Players should create passwords that are unique and hard to decipher.

2. Enable Two-Factor Authentication (2FA)

Two-factor authentication (2FA) provides an additional security layer on GameZone online platforms. When enabled, it requires a secondary verification code sent to a user’s mobile phone to complete the login process.

Benefits of using 2FA:

  • Prevents unauthorized access, even if passwords are exposed
  • Adds extra verification for every login attempt

This security feature is highly beneficial for players frequently engaging in multiplayer bingo games or downloading game applications. Gamers reduce unauthorized access risks significantly by implementing 2FA.

3. Avoid Logging in Over Public Wi-Fi

Connecting to GameZone through public Wi-Fi networks puts users at risk. Public or unsecured networks allow cybercriminals to intercept data on the network, including login credentials.

Safer alternatives include:

  • Using private and secure network connections at home.
  • Avoiding logins from shared or public devices.
  • Relying on mobile data for safer gameplay while traveling or away from home.

These preventive measures ensure a secure experience, wherever the player may be.

4. Update Devices and Apps Regularly

Neglected updates on devices or casino platforms expose users to software vulnerabilities. Regular updates deliver patches and fixes to enhance protection against hackers.

Best practices for keeping systems updated:

  • Install updates for operating systems and browsers at regular intervals.
  • Download GameZone apps and updates officially from trusted sources.
  • Avoid using third-party versions of GameZone applications.

Updated devices and applications offer smoother and more secure sessions, ensuring that accounts remain safeguarded.

5. Log Out After Playing Sessions

Failing to log out from GameZone accounts increases the risk of unauthorized access, especially on shared or public devices. Ensuring account disconnection after gameplay is a simple yet effective habit.

Steps to improve logout practices:

  • Avoid saving login details when using shared devices.
  • Clear cache and browsing data after accessing accounts.
  • Make it a point to log out systematically after every session.

Regularly logging out minimizes the chances of account breaches and maintains better security for PHBingo accounts.

6. Beware of Phishing Scams

Phishing scams involve fake emails or messages impersonating official GameZone communications to trick players into revealing login information. These scams often include links to malicious websites posing as the platform’s login page.

Signs of phishing schemes include:

  • Emails claiming “urgent account issues” requiring immediate action
  • Links to web pages that request sensitive login credentials
  • Emails sent from domains that look unofficial or are oddly spelled

Players should always enter their credentials through the official GameZone login page rather than clicking on suspicious links to avoid falling victim to such scams.

7. Monitor Account Activity Regularly

Checking account activity makes it easier to detect and resolve suspicious behavior or unauthorized logins. Reviewing recent account use helps players pinpoint breaches quickly.

Effective steps to manage account activity:

  • Change passwords immediately if irregular activity appears.
  • Reach out to GameZone support for assistance with securing compromised accounts.
  • Monitor recent logins and transactions for unrecognized activities.

Tracking account patterns ensures issues are addressed early, making it easier to control risks.

8. Use Secure Payment and Transaction Methods

Online bingo often involves linking accounts with payment methods. Securing financial data ensures that sensitive information isn’t exploited or mishandled.

Practical payment security tips include:

  • Using verified and reputable payment gateways.
  • Avoiding unauthorized transactions or sharing of payment details.
  • Double-checking URLs to ensure the payment page is official and secure.

Secure payment methods enhance the overall user experience while providing peace of mind for frequent players.

9. Avoid Sharing Account Credentials

Sharing login information with others, even with close friends, increases the risk of unauthorized access or account misuse. Keeping accounts private ensures better control over personal playing progress.

Reasons to avoid sharing login details:

  • Reduces the possibility of accidental account misuse.
  • Preserves account integrity and progress.
  • Prevents unknown individuals from accessing personal information.

Limiting account sharing eliminates these risks and ensures safety for all users.

10. Focus on Responsible Practices Alongside Security

Combining security precautions with responsible practices allows for a safe and balanced experience. GameZone promotes responsible practices by offering reminders and restrictions that prevent excessive gameplay.

By maintaining both security and healthy habits, players can enjoy a fun, worry-free environment.

Enhancing GameZone Experiences Through Security

Secure play for PHBingo accounts begins with adopting strong cybersecurity habits. Simple measures like using complex passwords, enabling two-factor authentication, and avoiding suspicious links create a robust system of protection. Regular account monitoring and updates further help reduce risks associated with online threats.

By reinforcing security steps, users gain confidence in their platforms, ensuring they can focus on enjoying PHBingo and other offerings worry-free.

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Features

Today’s Antizionism is Jew-Hatred

By HENRY SREBRNIK The Jewish world has grown darker. I’m not going to compare the anti-Jewish hate that has spread across this and other countries since October 7, 2023, to the Holocaust, but we know that Jewish life has become far more precarious. And so much of the hatred flies under the rubric of so-called “antizionism,” with people claiming that this isn’t “antisemitism.” But this is a false dichotomy. And we know it when we see it.

“Antizionism” is not about the now arcane historical debates that occurred mainly within Jewish communities from the 19th century through 1948, in which those who became Zionists sought to actualize the Jewish ties to biblical Israel and recreate a modern state. By “Zionists,” today’s enemies are not referring to supporters of the 19th century self-liberation movement of the Jewish people, whose goal was to establish a national home. They known little of this history. They’ve never heard of Theodor Herzl, Ahad Ha’am, Ber Borochov, Ze’ev Jabotinsky, or Chaim Weizmann.

As a derogatory slur, a pejorative, it simply means “Jew,” the way earlier words, now archaic, used to. Some call Jews “Zios.” They mean the Jewish people, who exist in opposition to everything good in the world, and who are figures of emblematic wickedness. In this they simply update what Nazis said a century ago. Hitler, too, was an “antizionist,” along with his racial antisemitism. It attacks Jews, here in Western countries like Canada – in the cities where they live, in the universities they attend, in the publishing houses where they send their manuscripts, and in the entertainment world where they act and sing. 

Note that it calls itself antizionism, not anti-Israelism, so that the net can grab virtually every Jew who simply wants to see Israel not destroyed – and that’s the vast, vast majority. We Jews know what it means, regardless of what our enemies claim. Would anyone think that the term antisemitism means hatred of Semites? 

Clearly a ludicrous idea; it was invented in the 19th century by a German Jew-hater, Wilhelm Marr, to make it sound more “racially scientific.” No one is fooled by that, of course, nor should they be by so-called “antizionism.” In its effects, it is for Jews a distinction with a negligible difference. It is meant to portray Jews as villains, and while it may fool some gullible people, it will deceive very, very few of us.

After all, as Michel Coren noted in “Roald Dahl’s Antisemitism Feels Painfully Familiar,” in the British magazine the Spectator March 16, “most Jewish people do in fact to varying degrees support Israel, partly because centuries of bigotry, violence, massacre, and attempted genocide have given them little alternative. They may oppose Israeli policy, may condemn the current government, may even want radical compromises, but there’s still support. And in the current climate of leftist and Islamist triumphalism, it’s all Zionism and none of it acceptable.”

Anti-Zionism is marked by three core “libels”: that “Zionists” are colonizers, guilty of apartheid, and committing genocide. (Actually, the only time we were settler-colonialists was when we conquered Canaan, but that was God’s doing!) Anti-Israel activists incorporate historical manifestations of anti-Jewish discrimination under the guise of anti-Zionist political activism, from the blood libel to Nazi-era tropes, mixed with contemporary academic theories. Anti-Zionism acts as a container for these historical tropes, blending them together with progressive talking points.

George Washington University professor Daniel Schwartz, in “Vocabulary Lesson,” Jewish Review of Books, Spring 2026, describes a pro-Palestinian demonstration in 2025 at his campus where a student held a placard with Israel at the center and spokes radiating outward to other evils: imperialism, white supremacy, even reproductive injustice. “This is not garden-variety political criticism of Israel policies or conduct. It invokes a symbolic architecture in which the Jewish state becomes the universal source of global suffering — a structure with deep resonance in antisemitic thought.”

Scholars argue that it is the third major iteration of discrimination against Jews. The first was anti-Judaism, based on religion, the second was antisemitism, focused on race, and the third, anti-Zionism, is a hatred of Jewish peoplehood. 

“Anti-Zionism transforms the very meaning of Zionism,” contends Adam Louis-Klein. “The Jew is reconstructed through a new symbolic logic and a new repertoire of stereotypes.” Where antisemites invoked the pseudo-biological figure of “the Semite” to cast Jews as an Oriental race infiltrating the West, anti-Zionists invoke the authority of the social sciences to recode the Jew as the “Zionist,” a European colonizer destined to commit genocide of a non-European population. 

“Erasing Jewish indigeneity and severing Jewish belonging to the land of Israel, anti-Zionism transforms the race polluter of antisemitism into the white settler of anti-Zionism,” he asserts in his March 24, 2026 Free Press article “Yes, Anti-Zionism Is Discrimination.” 

For this reason, he writes, it’s imperative that organizations and institutions committed to protecting Jews and fighting the scourge of Jew-hatred start condemning—clearly and without apology—antisemitism and antizionism. This goes to the moral core of the matter: the right of Jews to a homeland versus the bigotry of those who deny them that right.

After the Holocaust, explicit Jew-hatred became unfashionable in polite society, but the impulse never disappeared. The workaround was simple: separate Zionism from Judaism in name, then recycle every old anti-Jewish trope and pin it on “the Zionists.”

Henry Srebrnik is a professor of political science at the University of Prince Edward Island.

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Artificial Intelligence, Sports Data, and What It Means for Community Values

Artificial intelligence is becoming an increasingly visible part of modern life, shaping how information is analyzed and decisions are made. While often discussed in fields such as healthcare, finance, and education, sports analytics provides a particularly clear example of how these systems function in real time. For many readers, the relevance of this topic goes beyond sports itself and speaks to broader questions about technology and community values.

Within Jewish communities, where education, critical thinking, and ethical responsibility have long been central principles, the rise of AI invites meaningful discussion. Understanding how automated systems operate is not only a technical issue but also a cultural and intellectual one. In global digital environments, references to platforms such as 1xbet Republic of Ireland often appear in discussions about real-time data processing, illustrating how widely these technologies are applied.

From Human Judgment to Algorithmic Thinking

Traditionally, interpreting sports performance required human observation and experience. Analysts would review statistics, assess player form, and make informed judgments based on knowledge built over time. While this method remains valuable, it is now being supplemented by artificial intelligence.

AI systems can process large volumes of data instantly, identifying patterns and trends that might otherwise go unnoticed. This shift reflects a broader movement toward algorithmic thinking—where decisions are increasingly informed by data rather than intuition alone.

For communities that place a strong emphasis on learning and inquiry, this raises important questions. How should data be interpreted? What role should human judgment continue to play? And how do we ensure that reliance on technology does not replace thoughtful analysis?

What AI Systems Analyze

Modern AI models draw on a wide range of data inputs to generate insights. In the context of sports, this includes:

  • real-time performance data
  • historical comparisons
  • individual player metrics
  • behavioural patterns
  • external conditions

The ability to integrate these variables allows AI to produce highly detailed assessments. However, it also creates a layer of complexity that is not always easy to understand.

This challenge is particularly relevant in educational settings. As younger generations become more familiar with technology, there is a growing need to teach not only how to use these systems, but also how to question and evaluate them.

Ethics, Transparency, and Responsibility

The increasing role of AI naturally leads to ethical considerations. In Jewish thought, concepts such as responsibility, fairness, and accountability are deeply rooted and widely discussed. These ideas are highly relevant when considering how automated systems are designed and used.

One of the key concerns surrounding AI is transparency. When decisions are made by complex algorithms, it can be difficult to understand the reasoning behind them. This raises questions about trust and oversight.

Ensuring that AI systems are used responsibly requires a balance between innovation and ethical awareness. Community dialogue plays an essential role in this process, helping to define how technology should align with shared values.

A Community Conversation About the Future

The use of artificial intelligence in sports analytics may seem like a narrow topic, but it reflects a much larger transformation. Across many areas of life, data-driven systems are becoming the norm, influencing how information is processed and decisions are made.

For Jewish communities, this moment presents an opportunity for reflection and engagement. By approaching technology with curiosity, critical thinking, and a strong ethical framework, it is possible to better understand both its potential and its limitations.

Ultimately, the conversation about AI is not just about technology. It is about how communities adapt, preserve their values, and shape the future in a rapidly changing world.

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