Features
Famed biographer Walter Isaacson’s latest book examines how “Crispr” tecnnology developed and how it’s changing our world
By MARTIN ZEILIG During the recent rebroadcast of an interview on CBC Radio’s science show, Quirks & Quarks, Dr. Jennifer Doudna told how it “was a real shock” when she received an early morning telephone call notifying her of having been co-awarded the 2020 Nobel Prize in Chemistry.
She’s a humble person. But, she shouldn’t have been so surprised.
Doudna, a professor of molecular and cell biology at University of California, Berkeley, and her collaborator, a French professor and researcher in microbiology, genetics, and biochemistry at the Max Planck Institute in Berlin, Germany, were awarded the prize for the development of the CRISPR-Cas9 genome editing technique.
This meticulously researched book by author Walter Isaacson takes a reader into the quest by Doudna and Charpentier that eventually led to their breakthrough discovery. We see Doudna as a liberal minded and generous person, as well as a brilliant and driven research scientist.
Walter Isaacson, a professor of history at Tulane University, has been CEO of the Aspen Institute, chair of CNN, and an editor at Time Magazine. He is the author of “Leonardo da Vinci”, “The Innovators”, “Steve Jobs”, “Einstein: His Life and Universe”, “Benjamin Franklin: An American Life”, and “Kissinger: A Biography”, also the coauthor of “The Wise Men: Six Friends and the World They Made”.
The essence of CRISPR (an acronym for clustered regularly interspaced short palindromic repeats) is simple: It’s a way of finding a specific bit of DNA inside a cell.
“CRISPR technology also has the potential to transform medicine, enabling us to not only treat but also prevent many diseases. We may even decide to use it to change the genomes of our children. An attempt to do this in China has been condemned as premature and unethical, but some think it could benefit children in the future, notes online information. After that, the next step in CRISPR gene editing is usually to alter that piece of DNA. However, CRISPR has also been adapted to do other things too, such as turning genes on or off without altering their sequence.
“There were ways to edit the genomes of some plants and animals before the CRISPR method was unveiled in 2012 but it took years and cost hundreds of thousands of dollars,” says the science site.
“CRISPR has made it cheap and easy.
“CRISPR is already widely used for scientific research, and in the not too distant future many of the plants and animals in our farms, gardens or homes may have been altered with CRISPR. In fact, some people already are eating CRISPRed food.
“CRISPR is being used for all kinds of other purposes too, from fingerprinting cells and logging what happens inside them to directing evolution and treating gene drives.
“The key to CRISPR is the many flavours of “Cas” proteins found in bacteria, where they help defend against viruses. The Cas9 protein is the most widely used by scientists. This protein can easily be programmed to find and bind to almost any desired target sequence, simply by giving it a piece of RNA to guide it in its search.”
Isaacson describes how a young Doudna came home one day from grade school to find that her father had left a paperback issue of the book, “The Double Helix”, by James Watson, on her bed. That classic and compelling story about Watson and his collaborator Frances Crick’s (1916-2004) race to discover the structure of DNA delighted Doudna.
Years later, Watson praised Doudna for her role in, as the author writes, “the most important biological advance” since his codiscovery of the structure of DNA.
There are many other prominent and not so well known names, at least to the non-science community, referenced in this superb story.
“The inner workings of molecules may remain, for most people, as mysterious as those of microchips, but at least all of us will be a bit more aware of the beauty and power of both,” the author writes.
“By honoring CRISPR, a virus-fighting system found in nature, in the midst of a virus pandemic, the Nobel committee reminded us how curiosity-driven basic research can end up having very practical applications. CRISPR and COVID are speeding our entry into a life-science era. Molecules are becoming the new microchips.”
This book helps us to understand that brave new world.
“The Code Breaker: Jennifer Doudna, Gene Editing, and the Future of the Human Race”
by Walter Isaacson
(Simon & Schuster 536 pg. $40.00)
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Discover Your Ultimate Smooth at Sets on Corydon: Nanoplasty vs. Keratin vs. Japanese Straightening
Are you ready to wake up with flawless, effortless hair every single day? While standard straightening methods try to fit everyone into the same box, your hair has its own unique structure, strength, and history.
We offer three distinct, state-of-the-art smoothing and straightening systems. Finding the perfect match depends entirely on your hair type, your lifestyle, and your ultimate hair goals.
Here is exactly how they compare so you can choose the path to your most beautiful, resilient hair.
The Treatment Breakdown
1. The Elite Standard: Nanoplasty (Our Premier Selection)
Nanoplasty is a revolutionary, high-technical smoothing treatment that works at a deep cellular level. Using nanotechnology, nutrients and amino acids are deeply integrated right into the hair cortex (the inner core of the hair strand). It heals, seals, and straightens from the inside out without harsh chemicals.
- How it works: It uses an acidic formula triggered by specialized infrared heat to realign the hair bonds. It does not just coat the cuticle; it restructures it while infusing massive hydration.
- The Finish: Ultra-glossy, high-shine, sleek, and straight, while retaining natural movement and zero frizz.
- The Big Benefit: Formulated without formaldehyde or harsh chemicals. There are no fumes, no burning eyes, and you can wash your hair or tie it up the very same day.
- Longevity: Lasts up to 4 to 6 months.
2. The Classic De-Frizzer: Keratin Treatment
The traditional choice for managing unruly texture. Keratin acts like a protective shield, filling in the cracks along a compromised or distressed hair cuticle (the protective outer layer).
- How it works: A liquid keratin formula is sealed into the outer layer of the hair with a flat iron.
- The Finish: Soft, smooth, and incredibly manageable. It reduces curl volume by roughly 50 to 70% and completely deletes frizz, but leaves some of your natural body and bounce.
- The Big Benefit: Ideal for hair that has undergone chemical stress or bleaching. It acts like a temporary protein bandage to restore softness and cut your blow-dry time in half.
- Longevity: Lasts 3 to 4 months, gradually washing out over time.
3. The Permanent Sleek: Japanese Straightening (Thermal Reconditioning)
For those who want absolute, pin-straight hair that defies high humidity and never reverts.
- How it works: This is a permanent chemical process that physically breaks down the internal bonds of the hair, which are then precision-ironed perfectly flat and neutralized to lock in the new shape forever.
- The Finish: Mirror-smooth, pin-straight, glassy hair with zero wave or curl.
- The Big Benefit: It is completely permanent on the hair that is treated. Rain, humidity, and workouts will not change it. Only your new root growth will need touching up.
- Longevity: Permanent (requires root touch-ups every 6 to 9 months).
Which One Is Right For You?
| Feature | Nanoplasty | Keratin Treatment | Japanese Straightening |
| Primary Goal | Deep cellular repair, sleek straightening, intense gloss. | Frizz elimination, volume reduction, softer texture. | Permanent, absolute pin-straight results. |
| Hair Condition | Healthy to moderately sensitized or colored hair. | Highly compromised, bleached, or heat-distressed hair. | Healthy, resistant, coarse, or virgin hair only. |
| Chemical Type | Amino acids & organic acids (No formaldehyde fumes). | Cuticle-coating formulas (May contain standard preservatives). | Traditional alkaline straightening solution. |
| Post-Care Window | Wash or style immediately. No waiting period. | Must wait 48 to 72 hours before washing or tying up. | Must keep completely dry and straight for 48 to 72 hours. |
An Important Note on Hair Integrity: Beautiful hair is healthy hair. Because Japanese Straightening permanently alters the internal architecture of the hair strand, it is completely unsuitable for heavily highlighted, bleached, or fragile hair. If your hair has a history of heavy chemical processing, a customized Nanoplasty or Keratin Treatment will give you the breathtaking, smooth results you want while respecting and preserving the strength of your hair structure.
Let’s curate your perfect look. Book a structural hair analysis with us today, and let’s design a smoothing protocol tailored exactly to your hair’s unique signature.
Features
Why Digital Innovation Keeps Elevating PH Bingo Online in the Philippines
Bingo culture in the Philippines draws from decades of shared moments—barangay get-togethers, family weekends, office fundraisers, and local assemblies where cards, markers, and number calls set the pace of the room. The pull often comes from anticipation: one more number, one more match, one step closer to a winning pattern. That familiar rhythm now appears in PH Bingo Online, where the classic experience stays recognizable while the delivery shifts to a faster, more flexible digital format.
Digital innovation around online bingo centers on convenience and player experience rather than changing the heart of the game. Technology supports easier entry, cleaner interfaces, stronger security, and tools for time and budget awareness. Within this space, platforms such as GameZone position online bingo as a modern option that still respects traditional gameplay structure.
From Bingo Halls to Phone Screens: Convenience as the Main Upgrade
Offline bingo often required planning. Venue distance, session schedules, traffic, seating capacity, and start times shaped participation. For many players, the issue never involved lack of interest; the issue involved logistics.
Online access changes the path to play. A mobile device turns idle minutes into potential game time, whether that means a short session after work, a quick round during downtime, or weekend play without commuting. The bingo card format remains intact, and the core mechanics stay familiar—numbers called, cards tracked, patterns completed—while the steps around participation become simpler.
With increased accessibility, PH Bingo Online reaches players outside the usual venue radius: those who live far from halls, those with rotating schedules, and those who prefer home-based entertainment. Digital convenience broadens the audience without demanding a new learning curve.
Digital Innovation That Improves the Online Bingo Experience
Online bingo involves more than transferring a paper card onto a screen. Modern platforms refine the full player journey, from sign-in to gameplay flow, with upgrades designed to reduce friction.
Key improvements commonly found in PH Bingo Online environments include:
Faster access and session entry
Less waiting and fewer steps before joining gameplay, especially compared with traveling to a venue and lining up for a seat.
Cleaner interface design
Card tracking becomes easier with readable layouts, clear number displays, responsive controls, and features that reduce mis-clicks or confusion.
Mobile-first accessibility
Support for play across compatible devices, allowing sessions at home or on the go.
Stability and performance upgrades
Optimized apps and server infrastructure help reduce lag, disconnections, or slow loading during active rounds.
Secure account management
Stronger login protection and account verification processes help reduce risk related to unauthorized access and imitation sites.
Responsible gaming tools
Built-in reminders and control features encourage healthier play habits, especially for players who want structure around spending and time.
Each feature targets the experience around bingo without altering the basic identity: number calls, card matches, and pattern wins.
Why Bingo Matches Digital Attention Habits
Bingo’s appeal often sits in its balance. The game requires attention, but not intense strategy. Each number call triggers a quick scan and a small decision—mark or move on—creating a cycle of anticipation that feels active without becoming mentally exhausting.
Digital platforms amplify that comfort by removing distractions tied to offline logistics. Travel time, venue noise, managing physical cards, and tracking multiple paper boards become less of a concern. The focus narrows to the core rhythm of the game, which fits players seeking light entertainment with consistent suspense.
This structure helps explain repeat engagement. When online platforms deliver smooth navigation and stable performance, bingo becomes an easy-to-enter pastime that works well for casual play, short breaks, or end-of-day downtime.
GameZone and the Modern Bingo Hub Experience
GameZone’s appeal often connects to its mixed offering: familiar entertainment presented through a modern interface. Alongside popular card selections, the platform includes Bingo games on GameZone, creating a single space for players who prefer switching between categories without opening multiple apps.
A platform-style hub typically supports:
- one account across several game types
- consistent interface and navigation design
- partnerships with recognized game providers
- in-house titles aimed at convenience-focused play
- responsible play tools integrated into the experience
Risk Assessment for PH Bingo Online Players
Online bingo convenience comes with practical risks that benefit from awareness and simple safeguards.
Unofficial or imitation platforms
Risk level: High
Copycat sites can mimic branding and create account safety issues.
Tip: access GameZone only through its official website and official app channels.
Playing while distracted
Risk level: Moderate
Multitasking affects enjoyment, focus, and time awareness.
Tip: choose a calmer setting and treat the session as dedicated playtime.
Long sessions without breaks
Risk level: Moderate
Extended play can weaken awareness of time and spending.
Tip: use session reminders or set limits before starting.
Ignoring updates
Risk level: Low
Outdated versions may miss important fixes for security and performance.
Tip: keep apps updated to maintain stability and protection.
Tips for a Better PH Bingo Online Experience
Get comfortable with the interface
Knowing where controls sit, how cards display, and how sessions move improves confidence and reduces mistakes.
Choose the right timing
Short sessions after a stressful workday may feel better with a quick break first. A refreshed mindset often improves the experience.
Explore other bingo formats
Starting with PH Bingo provides familiarity, while exploring other Bingo games on GameZone introduces variety in pacing and format.
Prioritize entertainment over outcomes
A recreation-first mindset supports healthier expectations and more sustainable enjoyment.
Downloading the GameZone App Safely
A typical setup process starts with the official GameZone website, followed by account registration or login. After that, the platform provides steps for downloading the official app. Supported app stores may also host the app depending on device and availability.
Official sources help ensure access to current versions, updated security protections, and performance improvements tied to the latest release.
Responsible Gaming on a Licensed Platform
GameZone operates as a PAGCOR-licensed gaming platform, available only to individuals 21 years old and above. Responsible gaming support often includes:
- session reminders for time awareness
- spending controls for budget structure
- self-exclusion options for stronger personal limits
Frequently Asked Questions
What is PH Bingo Online?
PH Bingo Online refers to digital versions of classic bingo, designed to preserve the familiar card-and-number format while enabling online access.
How does online bingo differ from offline bingo?
Core rules often remain the same, while convenience features, interface design, and platform tools vary by provider.
Can the GameZone app be downloaded?
Download access typically begins through the official GameZone website after registration or login, with installation guidance provided. Availability may also extend to supported app stores.
Is GameZone legitimate?
GameZone operates under PAGCOR licensing and limits access to players aged 21 and above.
Why do responsible gaming tools matter?
Session reminders, spending controls, and self-exclusion options support balanced play habits and long-term sustainability.
Features
New book highlights relationship between Kabbalah and science
By MYRON LOVE In his new book, “The Relativity of Death: Part One: Basic Principles of Kabbalah of Information. Complete Theory of Information Space, Miracles and Maxwell’s Demon,” Dr. Eduard Shyfrin demonstrates the complementary relationship between Kabbalah – the ancient practice of Jewish mysticism – and science.
“The Relativity of Death” is a follow up to “From Infinity to Man: the Fundamental Ideas of Kabbalah Within the Framework of Information Theory and Quantum Physics,” Shyfrin’s previous work on the subject, which he published in 2018.
In his introduction to “The Relativity of Death”, the author, himself a scientist by training – observes that while “science is absolutely necessary for humankind, it nevertheless does not constitute the whole truth. Science is morally neutral,” he continues. “Two plus two equals four is neither good nor bad. Science doesn’t provide an answer to the basic questions about our existence: Why are we here? What is our mission? How should we live? Do we have a freedom of choice? Why are we destined to die? And finally, the famous question posted by Gottfried Leibniz as to why is there something rather than nothing?
“I believe that it is impossible and wrong to try to describe Creation while at the same time excluding the Creator.
“When I started reading the works of kabbalists,” he notes, ‘I realised that Kabbalah is deeply ‘scientific,’ that it is a theory of Creation of which our Universe is just a part. Kabbalah is not a textbook – it doesn’t provide equations and laws. Instead, it’s a live body comprised of the teachings and opinions of kabbalists, which often diverged.
“The main notions of Kabbalah,” he writes, “for example the notion of light, are not well defined. As the great kabbalist Rabbi Moshe Hayyim Luzzatto explained in his book, “Philosopher and Kabbalist,” the notion of ‘Light has no definition and is used as some sort of synonym for G-dliness.
“The original works of kabbalists,” he points out, “are very difficult to read and comprehend, since the main ideas are usually expressed through allegories, parables and hints. This makes them largely inaccessible to contemporary readers. With this in mind, I attempted to create the Theory of Kabbalah of Information based on traditional Kabbalah, Theory of Information and the body of scientific knowledge accumulated by humankind, written in simple language accessible to the reader.”
Eduard Shyfrin is a remarkable individual – a man of many parts. In addition to his roles as scientist and author – he has also published a children’s book – the Ukrainian-born Shyfrin is a musician who writes his own words and music, a billionaire, and an important community leader who generously supports his fellow Ukrainian Jews and our Israeli homeland.
Growing up during the last years of the Soviet Union though, it comes as no surprise that he knew nothing about Judaism except that he was Jewish. In the Soviet Union, being Jewish was simply a label that kept you from being accepted into top universities and leadership roles.
“We tried to hide out Jewishness,” he recalls. “I wanted to be a physicist but wasn’t accepted into university.”
Instead, he followed in his father’s footsteps and became a metallurgist. In 1983, he started work at a Ukrainian steel plant. Over the next few years, he was promoted from assistant foreman to manager to head of marketing.
He was able to earn a PhD in physical chemistry in 1993.
In 1993, he changed jobs – becoming a representative in Ukraine of a Hong Kong-based company called Linkfull. He was responsible for buying steel for export. In 1994, he joined forces with Alex Schnaider and co-founded a company called the Midland Group, with partner Alexander Shnaider. The company deals in steel, shipping, real estate, agriculture and sport ventures.
Shyfrin’s interest in Judaism was sparked by the arrival of Chabad rabbis in the lands of the former Soviet Union in the mid 1990s and, in particular, Rabbi David Bleich, the Chief Rabbi of Ukraine. Shyfrin recalls that Rabbi Bleich got him involved in Jewish charities. He helped rebuild the oldest synagogue in Kiev, provided funds for the Jewish schools in the city, and and financed the construction of the Jewish Education Centre in Kiev, which was dedicated to his late father.
Still, Shyfrin remained largely secular.
It was in 2002, he recalls, that he experienced a midlife crisis when he began questioning the meaning of life – and death.
“My rabbi,” he says, “encouraged me to commit to a more Jewish lifestyle. I began keeping kosher, putting on tefillin and studying Torah. I found in my Torah study that there were a lot of contradictions and inconsistencies in what I was reading in the Torah and what I had learned as a scientist.”
Shyfrin began to find his answers in Kabbalah, which he approached through a scientific perspective. As a result , he came to understand kabbalah and reality as “fundamentally information based and that physics and Torah describe different layers of the same structure”.
That epiphany led to his first book, which has sold around 8,000 copies. He followed up the book’s success by writing numerous articles for the Jerusalem Post. Shyfrin also gives a yearly lecture in London, where he now makes his home.
He is also the founder of the Shyfrin Alliance, an initiative dedicated to advancing understanding of Jewish mysticism and spiritual thought.
Alongside his delving into Jewish mysticism, Shyfrin remains very much involved in the real world and the crises affecting Israel, the Jewish people, and his Ukrainian homeland. He currently serves as Vice President of the World Jewish Congress, representing Ukraine. He continues to fund Jewish schools, synagogues and community centres across Ukraine and Russia.
Since the invasion of Ukraine, Shyfrin has helped finance evacuations of Jewish elderly people and children to Hungary and Israel and continues to support communities on a monthly basis.
“For me, a Jew is a Jew,” he has been quoted as saying. “It does not matter where he lives. We are one family.”
As for the rising antisemitism in Europe, he points out that – unlike the 1930s – today, we have Israel.
“Israel is our country and we must be strong enough to protect it,” he is quoted as saying..
“The Relativity of Death” was released in February, and, Shyfrin reports, has already sold over 5,000 copies. The book is available on Amazon and Kindle.
