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For one Jewish family, education about family cancer history pays dividends
When Sue Gorlin was a child and away at camp during the summer of 1960, her mother received some awful news: She was diagnosed with ovarian cancer, and doctors gave her six months to live.
But she underwent surgery and, defying the odds, made a full recovery.
Not long afterward, Sue’s aunt was diagnosed with the same illness, and in this case the outcome was bad: She died within two years.
Still a teenager, Sue didn’t quite understand what was going on because she was kept largely in the dark.
“Back then, it was called ‘the big C.’ Nobody talked about it,” Sue recalled in an interview. “My mother and her sister both had ovarian cancer, but they were never going to tell me. That’s how secretive it was.”
Only by chance in the mid-1990s did Sue learn the truth, when a cousin revealed the story and urged her to get tested for the BRCA1 and BRCA2 genetic mutations. Those mutations render carriers far more susceptible to breast and ovarian cancer than otherwise, and approximately one of every 40 Jewish women of Ashkenazi descent is a carrier — compared to about 1 in 400 women in the general U.S. population.
Sue, who at the time was living in Silver Spring, Maryland, got tested and learned she was not a carrier of a BRCA mutation. But she nonetheless decided to get an annual pelvic sonogram and ultrasound just to be on the safe side.
That decision would end up saving her life. About 10 years later a sonogram revealed a malignant growth on one of her ovaries that had not yet spread. She had surgery to remove it, then underwent five months of chemotherapy.
Today Sue, now 79, lives in Israel with her husband, Jacques. Their Gorlin Family Foundation is a major benefactor of Sharsheret, the American Jewish nonprofit that offers education, counseling and support to women facing breast cancer and ovarian cancer.
October has been recognized as National Breast Cancer Awareness Month since 1985, and several weeks ago President Biden proclaimed September as National Ovarian Cancer Awareness Month.
This October, Sharsheret is holding five webinars focused on the cancers, from “Facing Scanxiety” (Oct. 16) to “Artificial Intelligence and Breast Cancer: What Does the Future Hold?” (Oct 30), and coordinating hundreds of in-person events at schools, Jewish community centers, and synagogues across the country.
Marking breast cancer and ovarian cancer with two specially designated months is a lifesaving reminder: It gives people an opportunity to learn about their risk for cancer and about how to find the resources they need to protect their health,” said Sharsheret CEO Elana Silber. “During these two months, people are paying attention and understanding the urgent concerns in our community. As a result, we are seeing more investment in critical support programs and medical research.”
Because they are in a heightened risk category, Jews have extra reasons to undergo genetic testing and research their family history.
“If it hadn’t been for Sue knowing her family history, who knows if she’d be around today?” said Sue’s husband, Jacques. “When she discovered her ovarian cancer in 2009, there were no clinical trials, and we didn’t know about the services of Sharsheret.”
Knowledge of her family history also made all the difference for Sue’s daughter, Michal Gorlin Becker.
“Because of my family history, I was considered high-risk and already had genetic counseling years before,” said Michal, 49, a mother of four living in Jerusalem. “I knew that my mother had ovarian cancer, and that my great-aunt had died of it. So in 2016 I had my ovaries taken out.”
She continued to monitor her health. In April 2020, after Michal’s doctor at Jerusalem’s Shaare Zedek Medical Center had her do a biopsy, she received some bad news: She had breast cancer. The news arrived on the morning of her 46th birthday, just as she was preparing for her daughter’s bat mitzvah.
“I was expecting it, but not necessarily on that day,” Michal said.
Annual pelvic sonograms and ultrasounds helped save Sue Gorlin’s life, enabling her to catch a malignant growth in her ovaries early on. Sue, 79, now lives in Israel with her husband, Jacques Gorlin. (Courtesy of Gorlin family)
Fortunately, her cancer was at an early stage and had not yet metastasized. Michal started chemotherapy the day after the bat mitzvah. She did eight rounds of chemo every two weeks; the course of treatment took four months.
“I was very lucky in that the type of cancer I had — HER-negative — wasn’t biological, and it wasn’t related to any hormones, so I didn’t have to continue with pills,” Michal said. “I had a double mastectomy with immediate reconstruction. It was major surgery, but I’ve done the best I can to prevent any sort of recurrence.”
Michal attributes her success fighting the cancer in part to her physical fitness at the time of her diagnosis. She had run back-to-back marathons in January and February 2020 and felt she was in the best shape of her life.
“I was strong and positive,” Michal said. “This is why I was able to get through it.”
Still a runner, Michal ran the TCS New York City Marathon last year with Team Sharsheret.
Her mother, Sue, eventually retested herself after technological advancements made BRCA testing more discerning. Updated versions cover genetic deletions as well as mutations, and Sue discovered she had a deletion that had not been picked up in earlier tests. Now Sue sees her oncologist once a year but has MRIs and mammograms every six months, as well as the CA125 blood test recommended for ovarian cancer survivors.
It’s important to keep in mind that breast and ovarian cancers are not limited to those with genetic mutations and often have other causes, said Sharsheret’s genetics program manager, Peggy Cottrell.
“When we see multiple cases of ovarian cancer in the same family, the likelihood of it being an inherited cancer is higher,” Cottrell said. “If someone tests negatively for hereditary cancer but has a very strong personal and family history of cancer, an updated test or even a research study may be helpful. Speaking with a genetic counselor can help clarify the best course of action.”
Chicago attorney Daniel Gorlin, 44, who is the youngest of Jacques and Sue Gorlin’s four children, credits his mother’s survival and his sister’s health in part to education about the importance of knowing one’s family history of illness — a message Sharsheret emphasizes in its educational outreach.
“This knowledge is what saved their lives,” said Daniel, who is a member of Sharsheret’s Illinois Community Advisory Committee.
Daniel has gotten himself tested for the BRCA genetic mutation. (Men are also susceptible to breast cancer, and carriers of the mutation are at higher risk of not only male breast cancer but also melanoma, prostate and pancreatic cancer.)
“It’s a different day and age now. People are far more interested in their genetics than before,” Daniel said. “This is a moment in time when it’s too dangerous for these topics to be taboo.”
The key, Sharsheret leaders say, is to take action. Sharsheret offers free and confidential conversations with mental health professionals and genetic counselors as well as connections to peer supporters. They can be reached via email at clinicalstaff@sharsheret.org, by phone at 866 474-2774 or online at Sharsheret.org.
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The post For one Jewish family, education about family cancer history pays dividends appeared first on Jewish Telegraphic Agency.
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Iran, US Resume Oman-Mediated Nuclear Talks in Rome
US President Donald Trump’s Middle East envoy-designate Steve Witkoff gives a speech at the inaugural parade inside Capital One Arena on the inauguration day of Trump’s second presidential term, in Washington, DC, Jan. 20, 2025. Photo: REUTERS/Carlos Barria
i24 News – A new round of nuclear talks between Iran and the United States kicked off in Rome on Saturday, under the shadow of President Donald Trump’s threat to unleash military action if diplomacy fails.
Iran’s Foreign Minister Abbas Araqchi and Trump’s Middle East envoy Steve Witkoff will negotiate indirectly through an Omani official who will shuttle messages between the two sides, Iranian officials said, a week after a first round of indirect talks in Muscat that both sides described as “constructive.”
Araqchi and Witkoff interacted briefly at the end of the first round, but officials from the two countries have not held direct negotiations since 2015 under former US President Barack Obama.
Araqchi called on “all parties involved in the talks to seize the opportunity to reach a reasonable and logical nuclear deal.”
Trump told reporters on Friday: “I’m for stopping Iran, very simply, from having a nuclear weapon. They can’t have a nuclear weapon. I want Iran to be great and prosperous and terrific.”
Meanwhile, Israel has not ruled out an attack on Iran’s nuclear facilities in the coming months, according to an Israeli official and two other people familiar with the matter.
Trump, who ditched a 2015 nuclear pact between Iran and six powers during his first term in 2018 and reimposed crippling sanctions on Tehran, has revived his “maximum pressure” campaign on the country since returning to the White House in January.
Since 2019, Iran has breached and far surpassed the 2015 deal’s limits on its uranium enrichment, producing stocks far above what is necessary for a civilian energy program.
The post Iran, US Resume Oman-Mediated Nuclear Talks in Rome first appeared on Algemeiner.com.
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Reps. Dan Goldman and Chris Smith Issue Statement Condemning Shapiro Arson Attack As ‘Textbook Antisemitism’
Pennsylvania Gov. Josh Shapiro (D) holds a rally in support of US Vice President Kamala Harris’ Democratic presidential election campaign in Ambler, Pennsylvania, US, July 29, 2024. Photo: REUTERS/Rachel Wisniewski
Rep. Dan Goldman (D-NY) and Rep. Chris Smith (D-NJ) issued a statement condemning the recent arson attack against Gov. Josh Shapiro (D-PA) as a form of “textbook antisemitism.”
“Governor Shapiro is the Governor of Pennsylvania and has nothing to do with Israel’s foreign policy, yet he was targeted as an American Jew by a radicalized extremist who blames the Governor for Israel’s actions. That is textbook antisemitism,” the statement read.
Shapiro’s residence, the Pennsylvania governor’s mansion, was set ablaze on Sunday morning, hours after the governor hosted a gathering to celebrate the first night of the Jewish holiday of Passover. Shapiro said that he, his wife, and his children were awakened by state troopers knocking on their door at 2 am. The governor and his family immediately evacuated the premises and were unscathed.
Goldman and Smith added that the arson attack against Shapiro serves as “a bitter reminder that persecution of Jews continues.” The duo claimed that they “strongly condemn this antisemitic violence” and called on the suspect to “be held accountable to the fullest extent of the law.”
Pennsylvania State Police said that the suspect, Cody Balmer set fire to Shapiro’s residence over the alleged ongoing “injustices to the people of Palestine” and Shapiro’s Jewish faith.
According to an arrest warrant, Balmer called 911 prior to the attack and told emergency operators that he “will not take part in [Shapiro’s] plans for what he wants to do to the Palestinian people,” and demanded that the governor “stop having my friends killed.”
The suspect continued, telling operators, “Our people have been put through too much by that monster.”
Balmer later revealed to police that he planned to beat Shapiro with a sledgehammer if he encountered him after gaining access into his residence, according to authorities.
He was subsequently charged with eight crimes by authorities, including serious felonies such as attempted homicide, terrorism, and arson. The suspect faces potentially 100 years in jail. He has been denied bail.
Shapiro, a practicing Jew, has positioned himself as a staunch supporter of Israel. In the days following Hamas’s brutal slaughter of roughly 1,200 people across southern Israel on Oct. 7, 2023, Shapiro issued statements condemning the Palestinian terrorist group and gave a speech at a local synagogue. The governor also ordered the US and Pennsylvania Commonwealth flags to fly at half-mast outside the state capitol to honor the victims.
Shapiro’s strident support of the Jewish state in the wake of Oct. 7 also incensed many pro-Palestinian activists, resulting in the governor being dubbed “Genocide Josh” by far-left demonstrators.
US Senate Democratic Leader Chuck Schumer (NY) chimed in on the arson attack Thursday, urging the Justice Department to launch a federal investigation, claiming that the incident could be motivated by antisemitism.
Schumer argued that the arson attack targeting Shapiro, who is Jewish, left the Pennsylvania governor’s family in “anguish” and warned that it could serve as an example of “rising antisemitic violence” within the United States. He stressed that a federal investigation and hate crime charges may be necessary to uphold the “fundamental values of religious freedom and public safety.”
Thus far, Shapiro has refused to blame the attack on antisemitism, despite the suspect’s alleged comments repudiating the governor over his support for Israel. The governor has stressed the importance of allowing prosecutors to determine whether the attack constitutes a hate crime.
The post Reps. Dan Goldman and Chris Smith Issue Statement Condemning Shapiro Arson Attack As ‘Textbook Antisemitism’ first appeared on Algemeiner.com.
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US, Iran Set for Second Round of Nuclear Talks as Iranian FM Warns Against ‘Unrealistic Demands’
Iran’s Foreign Minister Abbas Araqchi attends a press conference following a meeting with Russia’s Foreign Minister Sergei Lavrov in Moscow, Russia, April 18, 2025. Tatyana Makeyeva/Pool via REUTERS
Iranian Foreign Minister Abbas Araghchi said a deal could be reached during Saturday’s second round of nuclear negotiations in Rome if the United States does not make “unrealistic demands.”
In a joint press conference with his Russian counterpart, Sergei Lavrov, Araghchi said that Washington showed “partial seriousness” during the first round of nuclear talks in Oman last week.
The Iranian top diplomat traveled to Moscow on Thursday to deliver a letter from Iran’s so-called Supreme Leader, Ayatollah Ali Khamenei, briefing Russian President Vladimir Putin on the ongoing nuclear talks with the White House.
“Their willingness to enter serious negotiations that address the nuclear issue only, without entering into other issues, can lead us towards constructive negotiations,” Araghchi said during the joint press conference in Moscow on Friday.
“As I have said before, if unreasonable, unrealistic and impractical demands are not made, an agreement is possible,” he continued.
Tehran has previously rejected halting its uranium enrichment program, insisting that the country’s right to enrich uranium is non-negotiable, despite Washington’s threats of military actions, additional sanctions, and tariffs if an agreement is not reached to curb the country’s nuclear activities.
On Tuesday, US special envoy Steve Witkoff said that any deal with Iran must require the complete dismantling of its “nuclear enrichment and weaponization program” — reversing his earlier comments, in which he indicated that the White House would allow Tehran to enrich uranium to a 3.67 percent threshold for a “civil nuclear program.”
During the press conference, Araghchi also announced he would attend Saturday’s talks in Rome, explaining that negotiations with the US are being held indirectly due to recent threats and US President Donald Trump’s “maximum pressure” campaign against Tehran — which aims to cut the country’s crude exports to zero and prevent it from obtaining a nuclear weapon.
“Indirect negotiations are not something weird and an agreement is within reach through this method,” Araghchi said.
He also indicated that Iran expects Russia to play a role in any potential agreement with Washington, noting that the two countries have held frequent and close consultations on Tehran’s nuclear program in the past.
“We hope Russia will play a role in a possible deal,” Araghchi said during the press conference.
As an increasingly close ally of Iran, Moscow could play a crucial role in Tehran’s nuclear negotiations with the West, leveraging its position as a veto-wielding member of the UN Security Council and a signatory to a now-defunct 2015 nuclear deal that imposed limits on the Iranian nuclear program in exchange for sanctions relief.
Known formally as the Joint Comprehensive Plan of Action (JCPOA), Trump withdrew the US from the deal in 2018.
Since then, even though Tehran has denied wanting to develop a nuclear weapon, the UN’s nuclear watchdog – the International Atomic Energy Agency (IAEA) – has warned that Iran has “dramatically” accelerated uranium enrichment to up to 60 percent purity, close to the roughly 90 percent weapons-grade level and enough to build six nuclear bombs.
During the press conference on Friday, Russian Foreign Minister Lavrov said that “Russia is ready to facilitate the negotiation process between Iran and the US regarding Tehran’s nuclear program.”
Moscow has previously said that any military strike against Iran would be “illegal and unacceptable.”
Russia’s diplomatic role in the ongoing negotiations could also be important, as the country has recently solidified its growing partnership with the Iranian regime.
On Wednesday, Russia’s upper house of parliament ratified a 20-year strategic partnership agreement with Iran, strengthening military ties between the two countries.
Despite Tehran’s claims that its nuclear program is solely for civilian purposes rather than weapon development, Western states have said there is no “credible civilian justification” for the country’s recent nuclear activity, arguing it “gives Iran the capability to rapidly produce sufficient fissile material for multiple nuclear weapons.”
The post US, Iran Set for Second Round of Nuclear Talks as Iranian FM Warns Against ‘Unrealistic Demands’ first appeared on Algemeiner.com.