Israeli forces kept up their military campaign in the Gaza Strip on Wednesday and told civilians to leave a refugee camp in the north of the Palestinian enclave after the war reached into Lebanon with the killing in Beirut of the Hamas deputy leader.

Israel has neither confirmed nor denied that it killed Saleh al-Arouri in a drone strike in the Lebanese capital on Tuesday. But military spokesperson Rear Admiral Daniel Hagari said Israeli forces were in a high state of readiness and prepared for any scenario.

The assassination was a further sign that the nearly three-month war between Israel and Hamas was spreading across the region, drawing in the West Bank, Hezbollah forces on the Lebanon-Israel border, and even Red Sea shipping lanes.

Arouri, 57, who lived in Beirut, was the first senior Hamas political leader to be assassinated since Israel began its offensive against the Palestinian terrorist group in response to its deadly rampage into Israeli towns on Oct. 7.

Hamas politburo member Hossam Badran said in a eulogy for Arouri: “We say to the criminal occupation [Israel] that the battle between us is open.”

Israel had long accused him of orchestrating attacks on its citizens. But a Hamas official said he was also “at the heart of negotiations” conducted by Qatar and Egypt over the outcome of the Gaza war and the release of Hamas-held Israeli hostages.

Hezbollah chief Sayyed Hassan Nasrallah was due to make a speech in Beirut later on Wednesday. Previously he had warned Israel against carrying out assassinations on Lebanese soil, vowing a “severe reaction.”

The heavily armed Hezbollah, a Hamas ally and an Iran-backed terrorist group, has been exchanging near-daily fire with Israel across Lebanon’s southern border since the Gaza war began. More than 100 Hezbollah fighters and two dozen civilians have been killed on Lebanese territory, as well as at least nine Israeli soldiers in Israel.

Following Arouri’s killing, the UN peacekeeping mission in Lebanon said any escalation “could have devastating consequences for people on both sides of the border.”

In Cairo, Egypt’s President Abdel Fattah al-Sisi told a delegation from the US Congress that the priority was to secure a ceasefire in Gaza.

Sisi stressed the need to prevent the conflict from widening across the region, a presidency statement said.

The Israeli military said in its daily briefing that “intensive battles” with terrorists were continuing in Gaza on Wednesday in the southern city of Khan Younis. It has said previously it is trying to flush out Hamas leaders in the area.

Residents and Palestinian media said Israeli forces bombed Al-Nusseirat refugee camp in the northern part of the Hamas-ruled enclave overnight and into Wednesday.

Israeli planes also dropped leaflets on Al-Nusseirat ordering people to leave seven districts.

“You are in a dangerous combat area. The IDF is operating heavily in your area of residence. For your safety the IDF urge you to immediately evacuate this area,” the leaflets said.

Israeli war planes and tanks also stepped up attacks on the Al-Bureij refugee camp.

Hamas’ armed wing said it had killed 10 Israeli soldiers in fighting in Al-Bureij and hit five tanks and troop carriers. The Israeli military said the number of its soldiers killed since its first incursion into Gaza on Oct. 20 had reached 177.

The war was triggered by a cross-border Hamas assault on Israeli towns on Oct. 7 in which Israel says 1,200 people were killed and some 240 hostages taken back to Gaza.

Since then Israel has waged a campaign of air strikes and ground operations in Gaza with the goal of incapacitating Hamas.

Iranian foreign ministry spokesman Nasser Kanaani said Arouri’s killing would “ignite another surge in the veins of resistance and the motivation to fight against the Zionist occupiers.”

Shortly before Arouri’s killing, Hamas’ paramount leader Ismail Haniyeh, who is also based outside Gaza, said the movement had delivered its response to an Egyptian-Qatari ceasefire proposal.

He reiterated that Hamas’ conditions entailed “a complete cessation” of Israel‘s offensive in exchange for further releases of hostages.

Israel believes 129 hostages remain in Gaza after some were released during a brief truce in late November and others were killed during air strikes and rescue or escape attempts.

Israel has vowed to keep fighting until it has wiped out Hamas but it is unclear what it plans to do with the enclave should it succeed, and where that leaves the prospect of an independent Palestinian state.

In Lisbon, the European Union’s foreign policy chief Josep Borrell said the international community must impose a solution to the conflict because the two parties would never be able to reach an agreement.

“If this tragedy doesn’t end soon, the entire Middle East might end up in flames,” he said.

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