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Hereditary cancers aren’t just a women’s problem. Jewish men need to take precautions too.

Bill Harris, a veteran Los Angeles photojournalist, didn’t think much of it when one morning in 2012 he woke up and found a tiny blood spot on the T-shirt he’d slept in. The next morning, he found blood in the same place on his chest — and went straight to his computer.

“Online, I could find only three things that would cause a man’s nipple to discharge blood: being an avid runner, which I wasn’t; having a subtropical fungus, which I didn’t; and breast cancer,” he said. “That was a pretty big shock.”

Harris, then just a few weeks shy of his 61st birthday, immediately called his doctor, who ordered a mammogram and ultrasound. They confirmed a cancerous growth in his right breast. Ten days later, a biopsy came back positive. The next month Harris got a right mastectomy, followed by the removal of his left breast half a year later.

“I walked into a woman’s imaging center and had to get into a pink paper robe,” he recalled. “All the women in the waiting room were staring at me.”

Like many other Ashkenazi men, Harris never had considered that he might have been born with a harmful mutation of the BRCA gene, which elevates the risk not only of breast cancer, but also of melanoma and prostate, ovarian and pancreatic cancer.

“Hundreds of other mutations in the BRCA gene are just as dangerous, but they’re not specific to Ashkenazim,” said Dr. Robert Sidlow, director of the Male BRCA Genetic Risk Program at New York’s Memorial Sloan Kettering Cancer Center. About 1 in 40 Ashkenazi Jews (those of Eastern European descent) carries the harmful mutation, compared to about 1 in 400 in the general population.

“The vast majority of patients I see are relatives of women who have breast or ovarian cancer and then get tested,” he said. Of BRCA mutation carriers, Sidlow added, “Most men are pretty happy to enroll in some kind of surveillance program once they get over the initial shock.”

Sidlow is on the Men’s Leadership Council at Sharsheret, the national Jewish nonprofit organization that educates the community about cancer risks and supports those with breast cancer and ovarian cancer.

Elana Silber, CEO of Sharsheret (Hebrew for “chain”), says it’s crucial that men with a family history of cancer undergo genetic counseling screening for BRCA and other hereditary cancer mutations.

Genetic testing is possible via a standard blood or saliva sample.

While Sharsheret is primarily considered a women’s organization, it has been using November — nicknamed Movember for its focus on men’s health — for an awareness campaign focused on Jewish men’s cancer risks.

“This is not only a women’s issue,” Silber said. “Family history is so important. When a man shares his family history with his doctor, he may not realize that he should mention that his mother had breast cancer or that his sister had ovarian cancer, as these are not generally ‘men’s diseases.’ They are not aware that these cancers could mean that they themselves are at increased risk for cancer and that they can pass on these mutations to the next generation – their daughters and their sons.”

If someone discovers he (or she) is a carrier of one of the genetic mutations with elevated cancer risks — not just BRCA but also such mutations as ATM, TP53, CHEK2, and PALB2 — there are various precautions they can take for themselves and their children. They can monitor their own health more closely, they can get encourage their children to test to see if they are carriers and, for any future children, take steps to prevent the mutated genes from being passed down.

For example, couples can conceive via in vitro fertilization, or IVF, and then test the embryos before implantation to ensure that only those unaffected by the genetic mutation are implanted.

While most women are aware of the risks of breast cancer, men generally are not — even though the disease strikes 2,500 men in the U.S. every year and kills about 500 of them, according to Sidlow. About 1-2% of men with the BRCA1 mutation and 6-7% of men with the BRCA2 mutation will develop cancer by age 80.

“This is why we recommend periodic mammograms starting at about age 50 for men who carry a BRCA2 mutation,” Sidlow said. “We like to educate these men on how to check their chests once a month and have a clinician do a breast checkup on them once a year.”

Since the BRCA1 and BRCA2 mutations also make prostate cancer more likely, men with either mutation should get PSA (prostate-specific antigen) levels in their blood tested annually beginning at age 40, rather than 50, the age at which screening generally begins, Sidlow said.

Sharsheret has been promoting the importance of learning one’s family history, genetic counseling and screening among both men and women. The 20-year-old organization also runs various peer support networks, offers financial assistance to cancer patients, provides mental health counseling and guidance to patients, caregivers, and their friends, and seeks to educate the broader Jewish community about cancer risks and support.

Peggy Cottrell, a certified genetic counselor at Sharsheret, said men in general are more reluctant to get regular checkups than women.

Ashkenazi Jewish men are at elevated risk not just of breast and prostate cancer but also of pancreatic cancer. Pancreatic cancer is particularly difficult because it’s tough to detect early enough and hard to treat. The five-year survival rate is only 11%. About 2% of BRCA1 carriers and 4% of BRCA2 carriers will develop pancreatic cancer, Sidlow estimated.

“Usually by the time pancreas cancer is clinically detected it has already spread microscopically to the liver,” Sidlow said. “But pancreas cancer is potentially curable if caught when the tumor is extremely small.”

Even among those with elevated risks, certain behaviors can improve one’s odds, such as avoiding obesity, smoking and excessive alcohol consumption.

Harris, the California photojournalist, is still fighting at age 71. While he overcame breast cancer 10 years ago, last year he was diagnosed with ampullary cancer, a rare disease related to his BRCA2 status that was discovered thanks to his participation in a UCLA study. Surgeons have removed his gall bladder, half his pancreas and part of his small intestine, and he has had to endure eight rounds of chemotherapy.

“I’m still working through the aftereffects of the chemo. I have to eat smaller quantities than before and take enzymes to supplement my digestive processes,” Harris said.

Meanwhile, his 37-year-old son discovered that he, too, carries the BRCA2 mutation, and he had a double prophylactic mastectomy and reconstruction at age 30 — just to be on the safe side.

“If there’s any history of breast, ovarian or prostate cancer in your family, get tested genetically so that you’re informed,” Harris advised. “Diagnoses happen way too late for men, and the danger is too big.”


The post Hereditary cancers aren’t just a women’s problem. Jewish men need to take precautions too. appeared first on Jewish Telegraphic Agency.

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Trump Curious Why Iran Has Not ‘Capitulated’ Amid US Military Buildup, Says Witkoff

US Special Envoy Steve Witkoff delivers a press conference upon the signing of the declaration on deploying post-ceasefire force in Ukraine, during the so-called ‘Coalition of the Willing’ summit, at the Elysee Palace in Paris, France, Jan. 6, 2026. Photo: Ludovic Marin/Pool via REUTERS

US President Donald Trump is curious as to why Iran has not yet “capitulated” and agreed to curb its nuclear program, as Washington builds up its military capability in the Middle East, Trump’s special envoy Steve Witkoff said.

“I don’t want to use the word ‘frustrated,’ because he understands he has plenty of alternatives, but he’s curious as to why they haven’t… I don’t want to use the word ‘capitulated,’ but why they haven’t capitulated,” Witkoff said during an interview on Saturday with Fox News’ “My View with Lara Trump,” hosted by the president’s daughter-in-law.

“Why, under this pressure, with the amount of seapower and naval power over there, why haven’t they come to us and said, ‘We profess we don’t want a weapon, so here’s what we’re prepared to do’? And yet it’s sort of hard to get them to that place.”

Trump has ordered a huge buildup of forces in the Middle East and preparations for a potential multi-week air attack on Iran. Iran has threatened to strike US bases if it is attacked.

IRAN DENIES SEEKING NUCLEAR WEAPONS

The United States wants Iran to give up enriched uranium which Washington says can potentially be used to make a bomb, as well as stop supporting terrorists in the Middle East and accept limits to its missile program.

Tehran says its nuclear program is peaceful but it is willing to accept some curbs on it in return for the lifting of financial sanctions. It rejects tying this to other issues such as missiles and support for armed groups.

“They’ve been enriching well beyond the number that you need for civil nuclear. It’s up to 60 percent [fissile purity],” Witkoff said. “They’re probably a week away from having industrial, industrial-grade bomb-making material, and that’s really dangerous.”

A senior Iranian official told Reuters on Sunday that Iran and the United States still have differing views over sanctions relief in talks.

Witkoff also said he has met at Trump’s direction with Iranian opposition figure Reza Pahlavi, son of the shah ousted in Iran’s 1979 Islamic Revolution. He did not provide further details of the meeting.

Pahlavi, who lives in exile, served as a rallying figure for some of Iran’s opposition during anti-government demonstrations last month in which thousands of people are believed to have been killed, the worst domestic unrest since the revolution era.

Earlier in February, Pahlavi said US military intervention in Iran could save lives, and urged Washington not to spend too long negotiating with Tehran’s clerical rulers on a nuclear deal.

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US-Iran Talks Expected Friday if Iran Sends Nuclear Proposal Soon, Axios Reports

Atomic symbol and USA and Iranian flags are seen in this illustration taken, September 8, 2022. Photo: REUTERS/Dado Ruvic/Illustration/File Photo

United States negotiators are ready to hold another round of talks with Iran on Friday in Geneva if they receive a detailed Iranian proposal for a nuclear deal in the next 48 hours, Axios reported on Sunday, citing a senior US official.

Reuters could not immediately verify the report.

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Khamenei Designates Larijani to Lead Iran’s Affairs During Protests, Military Threats

Iran’s Supreme National Security Council Secretary Ali Larijani speaks after meeting with Lebanese Parliament Speaker Nabih Berri, in Beirut, Lebanon, Aug. 13, 2025. Photo: REUTERS/Aziz Taher

i24 NewsIran’s Supreme Leader Ali Khamenei has reportedly assigned significant authority to former Revolutionary Guards commander and longtime political figure Ali Larijani in response to rising US and Israeli military threats, as well as nationwide unrest, according to a report by The New York Times.

The newspaper cites Iranian officials, members of the Revolutionary Guards, and former diplomats, noting that Khamenei has issued detailed instructions on succession and emergency decision-making should he be targeted in a potential strike.

Larijani, currently a top national security official, has been tasked with managing state affairs, overseeing the crackdown on protests, coordinating sensitive nuclear discussions with Washington, and liaising with allied nations including Russia, Qatar, and Oman.

“Larijani has been entrusted with responsibilities that cover both domestic security and international relations, effectively acting as Khamenei’s right-hand man during this period of heightened tension,” the report states.

Officials say Khamenei has prepared multiple layers of succession for key political and military positions and delegated powers to a close circle of confidants. While Larijani is not considered a likely successor to the Supreme Leader due to insufficient religious credentials, he is described as one of the regime’s most trusted crisis managers.

Iran has reportedly placed its armed forces on high alert, deployed missile systems near Iraq and in the Persian Gulf, and intensified military exercises. Special forces, intelligence units, and Basij militia battalions are prepared to deploy to major cities to suppress unrest and monitor suspected foreign operatives if conflict escalates.

The move comes amid continued diplomatic engagement over Tehran’s nuclear program. Despite ongoing negotiations, officials say Iran is operating under the assumption that a U.S. military strike is “inevitable and imminent.”

According to the report, Larijani tops the list of emergency successors, followed by Parliament Speaker General Mohammad Bagher Ghalibaf, with former president Hassan Rouhani also named as a potential fallback in extraordinary circumstances.

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