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Hereditary cancers aren’t just a women’s problem. Jewish men need to take precautions too.
Bill Harris, a veteran Los Angeles photojournalist, didn’t think much of it when one morning in 2012 he woke up and found a tiny blood spot on the T-shirt he’d slept in. The next morning, he found blood in the same place on his chest — and went straight to his computer.
“Online, I could find only three things that would cause a man’s nipple to discharge blood: being an avid runner, which I wasn’t; having a subtropical fungus, which I didn’t; and breast cancer,” he said. “That was a pretty big shock.”
Harris, then just a few weeks shy of his 61st birthday, immediately called his doctor, who ordered a mammogram and ultrasound. They confirmed a cancerous growth in his right breast. Ten days later, a biopsy came back positive. The next month Harris got a right mastectomy, followed by the removal of his left breast half a year later.
“I walked into a woman’s imaging center and had to get into a pink paper robe,” he recalled. “All the women in the waiting room were staring at me.”
Like many other Ashkenazi men, Harris never had considered that he might have been born with a harmful mutation of the BRCA gene, which elevates the risk not only of breast cancer, but also of melanoma and prostate, ovarian and pancreatic cancer.
“Hundreds of other mutations in the BRCA gene are just as dangerous, but they’re not specific to Ashkenazim,” said Dr. Robert Sidlow, director of the Male BRCA Genetic Risk Program at New York’s Memorial Sloan Kettering Cancer Center. About 1 in 40 Ashkenazi Jews (those of Eastern European descent) carries the harmful mutation, compared to about 1 in 400 in the general population.
“The vast majority of patients I see are relatives of women who have breast or ovarian cancer and then get tested,” he said. Of BRCA mutation carriers, Sidlow added, “Most men are pretty happy to enroll in some kind of surveillance program once they get over the initial shock.”
Sidlow is on the Men’s Leadership Council at Sharsheret, the national Jewish nonprofit organization that educates the community about cancer risks and supports those with breast cancer and ovarian cancer.
Elana Silber, CEO of Sharsheret (Hebrew for “chain”), says it’s crucial that men with a family history of cancer undergo genetic counseling screening for BRCA and other hereditary cancer mutations.
Genetic testing is possible via a standard blood or saliva sample.
While Sharsheret is primarily considered a women’s organization, it has been using November — nicknamed Movember for its focus on men’s health — for an awareness campaign focused on Jewish men’s cancer risks.
“This is not only a women’s issue,” Silber said. “Family history is so important. When a man shares his family history with his doctor, he may not realize that he should mention that his mother had breast cancer or that his sister had ovarian cancer, as these are not generally ‘men’s diseases.’ They are not aware that these cancers could mean that they themselves are at increased risk for cancer and that they can pass on these mutations to the next generation – their daughters and their sons.”
If someone discovers he (or she) is a carrier of one of the genetic mutations with elevated cancer risks — not just BRCA but also such mutations as ATM, TP53, CHEK2, and PALB2 — there are various precautions they can take for themselves and their children. They can monitor their own health more closely, they can get encourage their children to test to see if they are carriers and, for any future children, take steps to prevent the mutated genes from being passed down.
For example, couples can conceive via in vitro fertilization, or IVF, and then test the embryos before implantation to ensure that only those unaffected by the genetic mutation are implanted.
While most women are aware of the risks of breast cancer, men generally are not — even though the disease strikes 2,500 men in the U.S. every year and kills about 500 of them, according to Sidlow. About 1-2% of men with the BRCA1 mutation and 6-7% of men with the BRCA2 mutation will develop cancer by age 80.
“This is why we recommend periodic mammograms starting at about age 50 for men who carry a BRCA2 mutation,” Sidlow said. “We like to educate these men on how to check their chests once a month and have a clinician do a breast checkup on them once a year.”
Since the BRCA1 and BRCA2 mutations also make prostate cancer more likely, men with either mutation should get PSA (prostate-specific antigen) levels in their blood tested annually beginning at age 40, rather than 50, the age at which screening generally begins, Sidlow said.
Sharsheret has been promoting the importance of learning one’s family history, genetic counseling and screening among both men and women. The 20-year-old organization also runs various peer support networks, offers financial assistance to cancer patients, provides mental health counseling and guidance to patients, caregivers, and their friends, and seeks to educate the broader Jewish community about cancer risks and support.
Peggy Cottrell, a certified genetic counselor at Sharsheret, said men in general are more reluctant to get regular checkups than women.
Ashkenazi Jewish men are at elevated risk not just of breast and prostate cancer but also of pancreatic cancer. Pancreatic cancer is particularly difficult because it’s tough to detect early enough and hard to treat. The five-year survival rate is only 11%. About 2% of BRCA1 carriers and 4% of BRCA2 carriers will develop pancreatic cancer, Sidlow estimated.
“Usually by the time pancreas cancer is clinically detected it has already spread microscopically to the liver,” Sidlow said. “But pancreas cancer is potentially curable if caught when the tumor is extremely small.”
Even among those with elevated risks, certain behaviors can improve one’s odds, such as avoiding obesity, smoking and excessive alcohol consumption.
Harris, the California photojournalist, is still fighting at age 71. While he overcame breast cancer 10 years ago, last year he was diagnosed with ampullary cancer, a rare disease related to his BRCA2 status that was discovered thanks to his participation in a UCLA study. Surgeons have removed his gall bladder, half his pancreas and part of his small intestine, and he has had to endure eight rounds of chemotherapy.
“I’m still working through the aftereffects of the chemo. I have to eat smaller quantities than before and take enzymes to supplement my digestive processes,” Harris said.
Meanwhile, his 37-year-old son discovered that he, too, carries the BRCA2 mutation, and he had a double prophylactic mastectomy and reconstruction at age 30 — just to be on the safe side.
“If there’s any history of breast, ovarian or prostate cancer in your family, get tested genetically so that you’re informed,” Harris advised. “Diagnoses happen way too late for men, and the danger is too big.”
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Rubio Says ‘Historic’ Israel-Lebanon Talks Should Outline Framework for Peace
Smoke rises after an Israeli strike, amid escalating hostilities between Israel and Hezbollah, as the US-Israeli conflict with Iran continues, in southern Lebanon, March 24, 2026. Photo: REUTERS/Stringer
US Secretary of State Marco Rubio hosted a rare meeting between Israeli and Lebanese envoys in Washington on Tuesday, saying he hoped the two countries would agree to a framework for a peace process, even as Israel pressed its war on Hezbollah.
The two countries went into their first direct negotiations since 1983 with conflicting agendas, with Israel ruling out discussion of a ceasefire and demanding Beirut disarm Hezbollah, an Iran-backed terrorist group based in Lebanon that seeks Israel’s destruction.
But the presence of Rubio, President Donald Trump’s top diplomat and national security adviser, signaled Washington’s desire to see progress.
CRITICAL JUNCTURE IN MIDDLE EAST CRISIS
The meeting comes at a critical juncture in the conflict in the Middle East, a week into a fragile ceasefire between the United States, Israel, and Iran.
Iran says Israel‘s campaign against Hezbollah in Lebanon must be included in any agreement to end the wider war, complicating talks mediated by Pakistan aimed at averting further economic fallout.
The conflict that began with US-Israeli strikes on Iran on Feb. 28 has led to a major oil supply disruption, piling pressure on Trump to find an off-ramp.
Rubio opened the meeting between Israel‘s ambassador to the US, Yechiel Leiter, and his Lebanese counterpart, Nada Hamadeh Moawad, saying he hoped the talks could begin a process to permanently end the conflict in Lebanon and prevent Hezbollah, which he called a “terrorist proxy of Iran,” from threatening Israel.
The meeting marked a rare encounter between representatives of governments that have remained technically in a state of war since the modern state of Israel was established in 1948.
“This is a process, not an event. This is more than just one day. This will take time, but we believe it is worth this endeavor, and it’s a historic gathering that we hope to build on. And the hope today is that we can outline the framework upon which a permanent, lasting peace can be developed,” Rubio said.
Rubio was hosting Tuesday’s talks amid questions over his lack of in-person participation in talks with Iran, with the Republican president sending Vice President JD Vance to Islamabad over the weekend to lead the US negotiations.
Rubio was with Trump in Florida watching a mixed martial arts event as Vance announced in Pakistan that talks with the Iranians had concluded with no breakthrough.
State Department Counselor Michael Needham, US ambassador to the United Nations Mike Waltz, and US ambassador to Lebanon Michel Issa, a personal friend of Trump, were also participating in the talks on Tuesday.
LEBANON SEEKS CEASEFIRE
Lebanese President Joseph Aoun said in a statement on X as the meeting started that he hoped it would “mark the beginning of ending the suffering of the Lebanese people in general, and the southerners in particular.”
The Lebanese government led by Aoun and Prime Minister Nawaf Salam has called for negotiations with Israel despite objections from Hezbollah, reflecting worsening tensions between the Shi’ite Muslim group and its opponents.
Hezbollah opened fire in support of Tehran on March 2, sparking an Israeli offensive that has killed more than 2,000 people and forced 1.2 million from their homes, according to Lebanese authorities. Most of those killed have been Hezbollah terrorists, according to Israeli tallies.
Lebanese officials have said Moawad only has authority to discuss a ceasefire in Tuesday’s meeting.
But Israeli government spokesperson Shosh Bedrosian said Israel would not discuss a ceasefire.
Israeli Foreign Minister Gideon Saar told reporters in Jerusalem ahead of the meeting that talks would focus on the disarmament of Hezbollah, which he said must take place before Israel and Lebanon could sign any peace agreement and normalise relations.
He said Hezbollah was a problem for Israel‘s security and Lebanon‘s sovereignty that needed to be addressed to move relations to a different phase. “We want to reach peace and normalization with the state of Lebanon,” he said.
The Lebanese state has been seeking to disarm Hezbollah peacefully since a war between the terrorist group and Israel in 2024. Efforts by Lebanon to disarm it by force risk igniting conflict in a country shattered by civil war from 1975 to 1990. Moves against Hezbollah by a Western-backed government in 2008 prompted a short civil war.
The current government banned Hezbollah’s military wing after it opened fire on Israel last month.
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Italy Suspends Defense Cooperation Deal With Israel as Trump Turns on Meloni
Italy’s Prime Minister Giorgia Meloni listens to debate, after she reported on her government’s actions and is expected to speak on the latest developments in Iran, at the lower house of Parliament in Rome, Italy, April 9, 2026. Photo: REUTERS/Remo Casilli
Italy’s Prime Minister Giorgia Meloni said on Tuesday her government had suspended a defense cooperation deal with Israel, reflecting frayed ties between previously close allies as the conflicts in the Middle East continue.
Meloni‘s right-wing government has been one of Israel‘s closest friends in Europe, but in recent weeks it has criticized its attacks on the Iran-backed terrorist group Hezbollah in Lebanon, which have killed hundreds and injured thousands.
Israel also fired warning shots last week at Italian troops serving in Lebanon under a UN mandate, causing damage to a vehicle.
“When there are things we don’t agree with, we act accordingly,” Meloni told reporters on the sidelines of a wine fair in Verona, northern Italy.
“In light of the current situation, the government has decided to suspend the automatic renewal of the defense agreement with Israel,” she added.
Meloni‘s announcement marked another diplomatic realignment for her right-wing government, coming a day after she criticized another close ally, US President Donald Trump, for his attacks on Pope Leo.
A source close to the matter, who requested anonymity, said Meloni took the decision on Monday with her foreign and defense ministers, Antonio Tajani and Guido Crosetto, as well as Deputy Prime Minister Matteo Salvini.
Israel‘s foreign ministry played down the consequences.
“We have no security agreement with Italy. We have a memorandum of understanding from many years ago that has never contained any substantive content. This will not affect Israel‘s security,” it said in a statement.
MELONI CHANGES TACK
Meloni has been in power since 2022 and will face a general election by late 2027.
“It’s a repositioning,” Lorenzo Castellani, political historian at Rome’s Luiss University, told Reuters.
“She’s afraid that a sizeable portion of the electorate, even among the center-right, will become highly critical of Trump and Netanyahu and of the effects of this war on Iran on the economy,” he added, referring to Israeli Prime Minister Benjamin Netanyahu,
Italy’s opposition parties had long called for a stop to the deal with Israel.
Signed in 2003 by the government of then Prime Minister Silvio Berlusconi, the memorandum entered into force in 2006 and was subject to automatic renewals every five years unless one of the parties withdraws.
It spans fields including procurement, training and the “import, export, and transit of defense and military equipment.”
As diplomatic tensions have risen, Rome last week summoned the Israeli ambassador to protest over the incident involving Italian troops in Lebanon. Then on Monday, Netanyahu’s government summoned the Italian ambassador “to discuss the situation in Lebanon.”
TRUMP TURNS ON MELONI
Meanwhile, Trump told an Italian newspaper on Tuesday that Meloni lacks courage and has let Washington down.
Meloni had been a vociferous supporter of Trump, but she distanced herself from him after he went to war with Iran in February, and on Monday she openly criticized him for lashing out at Pope Leo, saying his verbal assault was “unacceptable.”
Trump responded in an interview with Corriere della Sera, saying Meloni was “very different from what I thought” and denouncing her for refusing to help re-open the Strait of Hormuz, which has been blocked by Iran.
“I’m shocked by her. I thought she had courage. I was wrong,” he was quoted as saying in the Italian-language article.
The White House declined to comment on the reported quotes. Meloni‘s office also declined to comment, but politicians of all stripes rallied to her defense, including Foreign Minister Antonio Tajani, head of the coalition Forza Italia party.
“We are, and will remain, sincere supporters of Western unity and steadfast allies of the United States, but that unity is built on loyalty, respect, and mutual frankness,” he said, applauding Meloni for denouncing Trump‘s attack on the pope.
Trump‘s criticism marked a dramatic change in tone toward Meloni, the only European leader to attend his inauguration in 2025 and whom he had hailed as “a great leader” just one month ago.
On Tuesday he accused her of failing to back US efforts to tackle Iran’s nuclear program and guarantee energy flows through the Gulf, saying she wanted America “to do the job for her.”
Asked about her condemnation of his comments on Pope Leo, he said: “She is the one who is unacceptable, because she does not care whether Iran has a nuclear weapon and would blow Italy up in two minutes if it had the chance.”
The reprimand capped a tumultuous month for Meloni, who lost a crunch referendum on judicial reform in March and then saw her political ally Viktor Orban ousted from power in Hungary.
The US-Israeli war in the Gulf threatens to upend the economy with surging energy costs and is hugely unpopular with Italians, putting Meloni on a collision course with Trump.
Seeking to distance herself from the conflict, she refused to let US fighters use an airbase in Sicily for combat operations in Iran last month, before suspending the military cooperation pact with Israel this week.
Trump said the surge in energy prices should have encouraged Italy, which is heavily dependent on oil and gas imports, to help re-open the Strait of Hormuz.
“They pay the highest energy costs in the world and are not even ready to fight for the Strait of Hormuz … They depend on Donald Trump to keep it open,” Trump said.
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US, Iran May Resume Talks This Week Despite Port Blockade
A vessel at the Strait of Hormuz, off the coast of Oman’s Musandam province, April 12, 2026. Photo: REUTERS
Talks to end the Iran war could resume in Pakistan over the next two days, US President Donald Trump said on Tuesday, after the collapse of weekend negotiations prompted Washington to impose a blockade on Iranian ports.
Gulf, Pakistani, and Iranian officials also said negotiating teams from the US and Iran could return to Pakistan later this week, though one senior Iranian source said no date had been set.
“You should stay there, really, because something could be happening over the next two days, and we’re more inclined to go there,” Trump was quoted as saying in an interview with the New York Post.
While the US blockade drew angry rhetoric from Tehran, signs that diplomatic engagement might continue helped calm oil markets, pushing benchmark prices below $100 on Tuesday.
The highest-level talks between the two adversaries since the 1979 Islamic Revolution ended in Islamabad without a breakthrough, raising doubts over the survival of a two-week ceasefire that still has a week to run.
Since the United States and Israel began the war on Feb. 28, Iran effectively shut the Strait of Hormuz to nearly all vessels except its own, saying passage would be permitted only under Iranian control and subject to a fee. Nearly a fifth of global oil and gas supplies previously flowed through the narrow waterway, making the fallout widespread.
In a countermeasure, the US military said it began blocking shipping traffic in and out of Iran‘s ports on Monday. Tehran has threatened to hit naval ships going through the strait and to retaliate against its Gulf neighbors’ ports.
IMF CUTS GROWTH OUTLOOK
US Central Command said the blockade of Iranian ports involved more than 10,000 US military personnel, more than a dozen warships, and dozens of aircraft.
“During the first 24 hours, no ships made it past the US blockade and 6 merchant vessels complied with direction from US forces to turn around to re-enter an Iranian port on the Gulf of Oman,” CENTCOM said in a statement posted on X.
Shipping data showed the blockade had made little difference to Strait of Hormuz traffic on Tuesday, with at least eight ships crossing the waterway.
The latest standoff has further clouded the outlook for global energy security and the supply of goods that rely on petroleum.
On Tuesday, the International Monetary Fund cut its growth outlook and said the global economy would teeter on the brink of recession if the conflict worsens and oil stays above $100 per barrel into 2027.
The International Energy Agency slashed its forecasts for global oil supply and demand growth, saying both are now expected to fall from 2025 levels.
The US’ NATO allies including Britain and France said they would not be drawn into the conflict by taking part in the blockade, although they have offered to help safeguard the strait by drawing together a defensive multilateral mission to assist when an agreement is in place.
China, the main buyer of Iranian oil, said the US blockade was “dangerous and irresponsible” and would only aggravate tensions.
PROPOSAL FOR 20-YEAR SUSPENSION OF NUCLEAR ACTIVITY
US Vice President JD Vance, who led Washington’s delegation in Pakistan, has said Trump was adamant that any enriched nuclear material must be removed from Iran and a mechanism be established to verify that Iran is not developing nuclear weapons.
A source briefed on the matter confirmed reports that the US had proposed a 20-year suspension of all nuclear activity by Iran “with all sorts of restrictions.”
Two Iranian sources said Iran had rejected the proposal, suggesting a halt of just three to five years.
One source involved in the negotiations in Pakistan said backchannel talks since the weekend had produced good progress in closing the gap on the nuclear issue, bringing the two sides closer to a deal that could be put forward at a new round of talks.
Complicating Pakistan’s mediation efforts, Israel has continued targeting Iran-backed terrorist group Hezbollah in Lebanon. Israel and the United States say that campaign is not covered by the ceasefire, while Iran has insisted it is.
Israeli and Lebanese envoys were to meet in Washington on Tuesday in a rare encounter also expected to be attended by Secretary of State Marco Rubio. Lebanon’s government has sought negotiations with Israel despite objections from Hezbollah.
Israel continued to target Hezbollah after the Iran ceasefire was announced last week, but later said it was willing to discuss a separate ceasefire with the Lebanese government.
Regarding Iran, Israeli Foreign Minister Gideon Saar told reporters in Jerusalem on Tuesday: “We will never allow Iran to obtain nuclear weapons … The enriched materials must be removed from Iran.”
CEASEFIRE STILL HOLDING
With the war unpopular at home and rising energy prices causing political blowback, Trump paused the US-Israeli bombing campaign last week after threatening to destroy Iran‘s bridges and power grid unless it reopened the strait.
A Reuters/Ipsos poll conducted from April 10 to 12 after the ceasefire was announced showed that 35% of Americans approve of US strikes against Iran, down from 37% a week earlier.
The ceasefire has largely held over its first week despite sharp rhetoric from both sides.
An Iranian military spokesperson called any US restrictions on international shipping “piracy,” while Trump said that Iran‘s navy had been “completely obliterated” and that only a small number of “fast-attack ships” remained.
“Warning: If any of these ships come anywhere close to our BLOCKADE, they will be immediately ELIMINATED,” Trump wrote on social media.