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Hereditary cancers aren’t just a women’s problem. Jewish men need to take precautions too.

Bill Harris, a veteran Los Angeles photojournalist, didn’t think much of it when one morning in 2012 he woke up and found a tiny blood spot on the T-shirt he’d slept in. The next morning, he found blood in the same place on his chest — and went straight to his computer.

“Online, I could find only three things that would cause a man’s nipple to discharge blood: being an avid runner, which I wasn’t; having a subtropical fungus, which I didn’t; and breast cancer,” he said. “That was a pretty big shock.”

Harris, then just a few weeks shy of his 61st birthday, immediately called his doctor, who ordered a mammogram and ultrasound. They confirmed a cancerous growth in his right breast. Ten days later, a biopsy came back positive. The next month Harris got a right mastectomy, followed by the removal of his left breast half a year later.

“I walked into a woman’s imaging center and had to get into a pink paper robe,” he recalled. “All the women in the waiting room were staring at me.”

Like many other Ashkenazi men, Harris never had considered that he might have been born with a harmful mutation of the BRCA gene, which elevates the risk not only of breast cancer, but also of melanoma and prostate, ovarian and pancreatic cancer.

“Hundreds of other mutations in the BRCA gene are just as dangerous, but they’re not specific to Ashkenazim,” said Dr. Robert Sidlow, director of the Male BRCA Genetic Risk Program at New York’s Memorial Sloan Kettering Cancer Center. About 1 in 40 Ashkenazi Jews (those of Eastern European descent) carries the harmful mutation, compared to about 1 in 400 in the general population.

“The vast majority of patients I see are relatives of women who have breast or ovarian cancer and then get tested,” he said. Of BRCA mutation carriers, Sidlow added, “Most men are pretty happy to enroll in some kind of surveillance program once they get over the initial shock.”

Sidlow is on the Men’s Leadership Council at Sharsheret, the national Jewish nonprofit organization that educates the community about cancer risks and supports those with breast cancer and ovarian cancer.

Elana Silber, CEO of Sharsheret (Hebrew for “chain”), says it’s crucial that men with a family history of cancer undergo genetic counseling screening for BRCA and other hereditary cancer mutations.

Genetic testing is possible via a standard blood or saliva sample.

While Sharsheret is primarily considered a women’s organization, it has been using November — nicknamed Movember for its focus on men’s health — for an awareness campaign focused on Jewish men’s cancer risks.

“This is not only a women’s issue,” Silber said. “Family history is so important. When a man shares his family history with his doctor, he may not realize that he should mention that his mother had breast cancer or that his sister had ovarian cancer, as these are not generally ‘men’s diseases.’ They are not aware that these cancers could mean that they themselves are at increased risk for cancer and that they can pass on these mutations to the next generation – their daughters and their sons.”

If someone discovers he (or she) is a carrier of one of the genetic mutations with elevated cancer risks — not just BRCA but also such mutations as ATM, TP53, CHEK2, and PALB2 — there are various precautions they can take for themselves and their children. They can monitor their own health more closely, they can get encourage their children to test to see if they are carriers and, for any future children, take steps to prevent the mutated genes from being passed down.

For example, couples can conceive via in vitro fertilization, or IVF, and then test the embryos before implantation to ensure that only those unaffected by the genetic mutation are implanted.

While most women are aware of the risks of breast cancer, men generally are not — even though the disease strikes 2,500 men in the U.S. every year and kills about 500 of them, according to Sidlow. About 1-2% of men with the BRCA1 mutation and 6-7% of men with the BRCA2 mutation will develop cancer by age 80.

“This is why we recommend periodic mammograms starting at about age 50 for men who carry a BRCA2 mutation,” Sidlow said. “We like to educate these men on how to check their chests once a month and have a clinician do a breast checkup on them once a year.”

Since the BRCA1 and BRCA2 mutations also make prostate cancer more likely, men with either mutation should get PSA (prostate-specific antigen) levels in their blood tested annually beginning at age 40, rather than 50, the age at which screening generally begins, Sidlow said.

Sharsheret has been promoting the importance of learning one’s family history, genetic counseling and screening among both men and women. The 20-year-old organization also runs various peer support networks, offers financial assistance to cancer patients, provides mental health counseling and guidance to patients, caregivers, and their friends, and seeks to educate the broader Jewish community about cancer risks and support.

Peggy Cottrell, a certified genetic counselor at Sharsheret, said men in general are more reluctant to get regular checkups than women.

Ashkenazi Jewish men are at elevated risk not just of breast and prostate cancer but also of pancreatic cancer. Pancreatic cancer is particularly difficult because it’s tough to detect early enough and hard to treat. The five-year survival rate is only 11%. About 2% of BRCA1 carriers and 4% of BRCA2 carriers will develop pancreatic cancer, Sidlow estimated.

“Usually by the time pancreas cancer is clinically detected it has already spread microscopically to the liver,” Sidlow said. “But pancreas cancer is potentially curable if caught when the tumor is extremely small.”

Even among those with elevated risks, certain behaviors can improve one’s odds, such as avoiding obesity, smoking and excessive alcohol consumption.

Harris, the California photojournalist, is still fighting at age 71. While he overcame breast cancer 10 years ago, last year he was diagnosed with ampullary cancer, a rare disease related to his BRCA2 status that was discovered thanks to his participation in a UCLA study. Surgeons have removed his gall bladder, half his pancreas and part of his small intestine, and he has had to endure eight rounds of chemotherapy.

“I’m still working through the aftereffects of the chemo. I have to eat smaller quantities than before and take enzymes to supplement my digestive processes,” Harris said.

Meanwhile, his 37-year-old son discovered that he, too, carries the BRCA2 mutation, and he had a double prophylactic mastectomy and reconstruction at age 30 — just to be on the safe side.

“If there’s any history of breast, ovarian or prostate cancer in your family, get tested genetically so that you’re informed,” Harris advised. “Diagnoses happen way too late for men, and the danger is too big.”


The post Hereditary cancers aren’t just a women’s problem. Jewish men need to take precautions too. appeared first on Jewish Telegraphic Agency.

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Israeli Intelligence: Iran’s Regime at Most Fragile Point Since 1999

Iran’s Supreme Leader Ayatollah Ali Khamenei listens to the national anthem as Air Force officers salute during their meeting in Tehran, Iran, February 7, 2025. Office of the Iranian Supreme Leader/WANA (West Asia News Agency)/Handout via REUTERS

i24 News – Israeli intelligence officials assess that Iran’s ruling Ayatollah regime is at its most fragile point in more than two decades, as nationwide protests continue to escalate.

The scale of the demonstrations and the government’s response have prompted deep concern in Jerusalem.

A near-total internet shutdown is being interpreted as a troubling signal of severe events unfolding on the streets, including widespread killings that remain largely undocumented. Despite protests erupting in roughly 100 cities across Iran, very little video footage has emerged, further underscoring the regime’s clampdown.

Israeli officials warn that the situation could pose a real threat to the stability of Tehran’s leadership if demonstrations continue to grow. However, sources stress that the outcome is highly uncertain. A potential collapse of the regime would not necessarily lead to a democratic government, and intermediate scenarios—such as the replacement of leaders with regents or puppet figures—are also possible.

“The situation is far more complex than it appears,” said a source familiar with security discussions to i24NEWS. “No one truly knows how events will unfold, and we are monitoring every development with extreme caution to determine the best response.”

For now, Prime Minister Benjamin Netanyahu’s approach is described internally as “monitoring, supporting, hoping.” Israel is keeping a careful distance, allowing Washington to take the lead in applying international pressure on Tehran, while ensuring that the protest movement cannot be linked to Jerusalem in any public way.

Israel’s security establishment continues to follow developments closely, preparing for multiple scenarios in an environment where uncertainty and volatility remain exceptionally high.

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‘Prepare Military Defenses,’ Top US Officials Warn Trump as He Contemplates Strike on Iran

US President Donald Trump speaks during a swearing-in ceremony of Special Envoy Steve Witkoff in the Oval Office at the White House in Washington, DC, US. Photo: Kent Nishimura via Reuters Connect.

i24 NewsUS President Donald Trump has been warned by senior military officials that more time is needed to prepare for potential strikes against Iran, reports the Telegraph.

The president is reportedly considering military action in response to the violent crackdown by Iranian security forces against demonstrators.

Options under review include targeting elements of Iran’s security services implicated in the mass suppression of protests.

The demonstrations, which have erupted nationwide, have drawn international attention and heightened tensions in the region.

However, commanders stationed in the Middle East have cautioned that any immediate strike could provoke retaliatory attacks against US forces or allied interests. Officials told the White House that US troops need to first “consolidate military positions and prepare defenses” before undertaking any operations that could escalate into a broader conflict.

The warnings reflect concerns over both operational readiness and regional stability. Iran’s military capabilities, including ballistic missiles and proxy forces, could enable swift retaliation, making careful planning essential.

Intelligence assessments are ongoing, with US officials also monitoring Tehran’s response to the protests, which have been met with lethal force by authorities.

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Mamdani denounces Hamas chants, but his delay draws scrutiny

New York City Mayor Zohran Mamdani is facing mounting scrutiny after a delayed response to a protest in which demonstrators chanted pro-Hamas slogans. The episode reopened lingering doubts among Jewish leaders and voters who have watched Mamdani stumble through earlier flashpoints.

In a statement shared with reporters Friday evening, Mamdani condemned the language used during a protest outside a Queens synagogue Thursday night. The demonstration targeted an event promoting real estate investment in the Jewish communities of Modi’in and Ma’ale Adumim, settlements in the occupied West Bank, and included chants of “Say it loud, say it clear, we support Hamas here.”

Mamdani said the rhetoric and displays at the protest were “wrong and have no place in our city.” An hour later, amid criticism that he had not explicitly named Hamas, he followed up in a post on X, “Chants in support of a terrorist organization have no place in our city.”

It echoed a similar episode after Mamdani’s election in November, when he issued a mixed response to a demonstration outside Manhattan’s Park East Synagogue that featured anti-Israel and antisemitic slogans. He initially questioned the use of a sacred place for an event promoting migration to Israel. He later clarified his statement and said he would consider legislation limiting protests outside synagogues.

Critics said the response, which took nearly a day, was slow and undercut Mamdani’s repeated pledges to protect Jewish New Yorkers, and raised fresh questions about what kind of mayor he intends to be. New York City is home to the largest concentration of Jews in the United States. New York Police Department data shows that antisemitic acts made up 57% of all reported hate crimes citywide in 2025.

A week earlier, on his first day in office, Mamdani — a democratic socialist whose strident criticism of Israel deepened rifts within New York City’s Jewish community during the election — had already drawn criticism from mainstream Jewish organizations for revoking two executive orders by former Mayor Eric Adams that adopted a controversial definition of antisemitism that includes some forms of anti-Zionism, and another penalizing city contractors who engaged in boycotts of Israel.

Mamdani’s response to the Thursday night Hamas chants was issued around  5 pm on Friday. By the time, many Shabbat-observant New Yorkers did not see the mayor’s condemnation until Saturday night.

Some allies who accepted Mamdani’s ideological position privately expressed surprise that the mayor did not immediately denounce the chants, given the predictability of the backlash and the stakes involved. During the election, Mamdani came under fire for his refusal to explicitly condemn the “globalize the intifada” slogan used at some pro-Palestinian protests, perceived by many as a call for violence against Jews.

Adam Carlson, a political polling and research expert, called Mamdani’s statement denouncing the Hamas chants reasonable but “not perfect,” after spending much of the day criticizing the mayor’s lack of response, even as Democratic elected officials and some of Mamdani’s progressive allies issued fierce condemnations. “This is not only hurtful to me,” Carlson wrote on X, “but it’s bad politics and distracts from his agenda.”

Former City Comptroller Scott Stringer, who is Jewish and ran in last year’s Democratic mayoral primary, was even more blunt. “I have never been as concerned about the direction of our city as I am today,” Stringer said in an interview. “We are not up to a strong start in bringing the city together.”

Stringer, who was an active leader in combating anti-Muslim hatred after 9/11, said he had hoped that Mamdani would focus on affordability and issues that unite New Yorkers across communities. “But if that’s not to be, then we will fight politically,” he said. He pointed to the upcoming June primaries for Congress and the State Assembly, in which some of Mamdani’s socialist allies — and candidates he has endorsed — could pay a political price. In New York, Stringer said, “we are at the epicenter of Jewish hate, and we’re not going to stand down and allow this to unfold without a political response.”

Speaking with reporters on Saturday, Mamdani declined to address why he didn’t respond immediately, but said his statement was “consistent with my own politics and my own policies.”

A recent poll found that 55% of non-Jewish voters in New York City say Jewish concerns about feeling threatened by Mamdani’s statements on Israel are an overreaction fueled by politics. By contrast, among a smaller sample of 131 Jewish respondents, 53% say they have reason to feel that way, given Mamdani’s statements and associations.

What other city leaders said

While Mamdani remained silent through much of Friday, other city leaders moved quickly. City Council Speaker Julie Menin, City Comptroller Mark Levine, Gov. Kathy Hochul and Attorney General Letitia James all issued statements strongly condemning the pro-Hamas chants.

Speaking Friday night at Park Avenue Synagogue in Manhattan, Menin, who is the first Jewish speaker in the council’s history, was cautious but optimistic about collaborating with Mamdani on issues related to antisemitism in Israel.

“The Torah reminds us that leadership does not emerge from a place of peace, but from a place of struggle,” Menin told congregants. “When it comes to fighting for our Jewish community, I promise I will be the leader that you can count on — one who stands up to hate, who is not afraid to speak out, and who will not look away when it is uncomfortable or inconvenient.”

Levine, who is also Jewish, said, “There is no ambiguity” in condemning the support of a terrorist organization. “This cannot be normalized or excused,” he wrote on X. “Truly reprehensible.”

Hochul, who is running for reelection this year, said in a joint appearance with Mamdani last week that in her upcoming State of State address on Tuesday, she will announce safety zones around houses of worship “where people can go freely to a safe place without threats of violence or protests.”

The post Mamdani denounces Hamas chants, but his delay draws scrutiny appeared first on The Forward.

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