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Many peptides sound like Yiddish words. Here’s why.
(JTA) — A growing number of Americans are injecting themselves with peptides they ordered online, often with no idea what’s in the vial, hoping to cure ailments and reverse aging. And for reasons that will soon be made clear, some of the peptides that make their way into the faddish and often gray-market concoctions have what appear to be Yiddish names.
But first, Pinchas Cohen, the pioneering scientist responsible for the naming quirk, wanted to say a few words about the real potential for mitochondrial-derived peptides.
Peptides represent a revolution in medicine, with potential for major new drug discoveries, the University of Southern California professor said. And the gray market fad worries him.
“These are potent biological molecules,” Cohen said. “They should be used under the supervision of a physician, and when they’re being produced in reliable manufacturing facilities — most of which is not happening right now.”
That said: about those names.
Cohen’s lab at USC has given the world SHLP (pronounced “schlep”), SHMOOSE, MENTSH, and a few others not yet published — including one called NOSH and another PUTZ. Each is a legitimate scientific acronym, carefully reverse-engineered to land on a Yiddish word.
SHLP stands for Small Humanin-Like Peptide. SHMOOSE expands to Small Human Mitochondrial ORF Over SErine tRNA. The names are light-hearted, but the science is serious. Naturally occurring SHMOOSE has been linked to a 30% increased risk of Alzheimer’s disease. MENTSH, after Cohen also named a company he founded, shows promise for treating diabetes.
Cohen has a rule that he doesn’t name things himself. That’s the students’ job. “I always give the students and postdocs the chance to name the project they’re working on,” he said. “But I get veto power. They’ve already learned that the best way to get me to say yes is to come up with something really cute.”
Not every Yiddish name comes from a Jewish lab member. MENTSH was coined by a Taiwanese-American colleague who grew up in the Bay Area. “Surrounded by Jews,” Cohen noted. “He probably knows more Yiddish words that I do.”
The first peptide Cohen co-discovered was named by someone else — a Japanese scientist who called it humanin. But the second was Cohen’s subtle nod to Jewish tradition. MOTS-c, pronounced “mots-see,” was quietly crafted to echo the Hebrew word motzi, as in the blessing over bread. “That was subtle,” Cohen said, “but it was on purpose.”
The discovery of MOTS-c and the peptides that followed represented something genuinely new in science. Researchers had known about peptides for generations — insulin, the diabetes treatment, is one — but those were found through conventional means, in glands and tissues where scientists knew to look. Cohen’s innovation was finding that mitochondrial DNA, the tiny separate genome inside mitochondria long thought to encode only energy-related proteins, secretly harbored an entirely hidden library of bioactive peptides. In places scientists weren’t looking, and in parts of the genome dismissed as structural, there were functional molecules with potential to treat disease.
His lab has now published about a dozen such peptides, with another dozen or two in preparation. The number of these microproteins that may ultimately exist in the human genome, Cohen said, could reach into the millions, transforming biology in ways that are only beginning to be understood.
Cohen, who goes by the nickname “Hassy,” was born in Israel and moved to the United States at 14, when his parents were posted to the Israeli embassy in Washington. He comes from deep Zionist roots. His father’s family has been in Israel since the 1880s, among the founders of the first Jewish community in Haifa. His grandfather studied biology in Berlin in 1904 and helped establish agricultural institutions in pre-state Israel.
Cohen did his medical training at the Technion in Haifa, then Stanford, then the University of Pennsylvania and UCLA, before joining USC 14 years ago as dean of the Leonard Davis School of Gerontology.
Though his family is Ashkenazi, Cohen didn’t grow up speaking Yiddish — his father studied at Berkeley, his mother at the London School of Economics — and his accent bears little trace of his origins. The Yiddish names, he said, are less about heritage than about fun, and about giving his team a sense of ownership over their work.
“My identity is deeply rooted in my Jewish and Israeli heritage,” he said. “I am delighted your publication took an interest.”
The key to healthfully aging, Cohen said, is diet and exercise. “And the best diet is the Mediterranean diet,” he said, noting Israel’s high life expectancy.
He belongs to a Kehillat Israel synagogue in Pacific Palisades, though the fires that swept through the neighborhood earlier this year, he said, “slowed things down a bit.”
Despite Cohens’s warnings about treatments that are so far unproven, wellness influencers keep pushing peptide treatments, and Health Secretary Robert F. Kennedy Jr. has vowed to loosen regulations on peptides. The Food and Drug Administration announced Wednesday that it will hold a meeting to weigh easing restrictions on more than a half dozen peptide injections.
Cohen is careful not to let enthusiasm for the science bleed into endorsement of the wellness industry that has appropriated it. Each peptide, he said, is its own unique compound with its own effects and risks, not a supplement to be ordered from a TikTok link. The revolution he envisions runs through clinical trials and FDA approval, not gray market vendors and cryptocurrency payments.
But he is optimistic. Somewhere in the vast molecular landscape his lab is mapping, he said, there are more discoveries waiting, and, almost certainly, more Yiddish words to find them.
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Let my people grow: Jewish online cannabis retailer braces for new federal law to take effect
For the past several years, Jewish cannabis company Tokin’ Jew has offered a little something to take the edge off just about every Jewish occasion.
High Holidays have you feeling stressed? Try “High, Honey,” the company’s THC-infused honey stick. Passover Seder dragging on a little too long? An edible called “4 Cups,” the first officially certified kosher-for-Passover THC gummy, will help get you through it.
Now the company that brought the world cannabis-infused chocolate Hanukkah gelt and THC-laced hamantaschen is facing a decidedly less festive future. In a couple months, the products responsible for the majority of its business will no longer be legal due to a change in federal law.
And it’s not just Tokin’ Jew. The new restrictions, set to take effect in December, threaten to upend a multibillion dollar e-commerce industry that has flourished for nearly a decade.
For co-founders Ben Kraim and Will Cohen, who have spent years building a business around the unlikely intersection of Judaism and cannabis, the change threatens to undo much of their lives’ work.
“It’s not easy being a Jewish weed brand, Kraim told the Forward. “Our brand is incredibly niche, so the prospect of losing access to the customer base we worked hard to build up is especially upsetting.”
What began as a humble meme account has grown into a thriving online operation, selling everything from novelty Judaica gifts and smoking accessories to kosher-certified edibles with clever names like “Apple of My Chai” and “Guava Nagila.”
The company has also cultivated a devoted community, bringing together observant and secular Jews, along with cannabis enthusiasts of all backgrounds, through a shared appreciation for Jewish humor and high-quality kush.
Now, Tokin’ Jew Flower, the division of their company, which Kraim said accounts for approximately 60 to 70 percent of sales, faces an uncertain future.
The legal foundations for Tokin’ Jew dates back to the 2018 Farm Bill, which legalized products containing no more than 0.3 percent delta-9 THC by dry weight. That provision created an opening for companies to manufacture and ship hemp and hemp-derived products, including THC gummies, across certain state lines without needing to abide by the state-by-state licensing systems governing recreational marijuana use.
A booming industry followed. But Kraim acknowledges that the relatively lax federal regulations created opportunities for “bad actors” to sell questionable products.
“I think everybody in this industry knew things were a little too good to be true,” he said.
What he and many others expected, however, was tighter rules, not the effective elimination of their business model.
“We all thought eventually the federal government was going to create more regulation in this space,” he said, adding that he would have welcomed stronger oversight.
“We like to joke that it’s our Jewish guilt that keeps us from selling a subquality product. But we absolutely support stricter regulation – something that would have been entirely feasible.”
Instead, another provision tucked into the federal spending bill signed by President Trump in November 2025 dramatically narrowed the definition of legal hemp. Under the new rules, finished products containing more than 0.4 milligrams per container of total THC and similarly intoxicating cannabinoids will no longer qualify as federally legal hemp.
The restrictions were originally scheduled to go into effect November 2026, but Congress granted a brief extension that pushed the deadline back to December 11.
According to Kraim, it is not only companies like theirs that will be affected. Growers, manufacturers, packaging businesses and warehouses may have to shut down altogether.
“These are people’s entire livelihoods that they now have to just set ablaze,” Kraim said.
“At least we have this brand that can take many shapes and can live on in so many other ways,” he said. “But if you’re a hemp farmer, you are in big trouble.”
The news comes just as Tokin’ Jew has been experiencing explosive growth. According to Kraim, the company now has approximately 250,000 followers across social media platforms, with its Instagram content reaching between 18 million and 22 million people monthly. Orders have roughly tripled over the past year.
But the founders’ relationship with their customers goes beyond sales.
From the beginning, Kraim, who was raised modern Orthodox, and Cohen, who was raised in a Reform community, viewed their company as a way to connect Jews to their identity through humor, particularly those who may feel alienated from more traditional expressions of Judaism.
That same sense of community was on full display when they announced the impending restrictions.
“We were flooded with comments and DMs and emails,” Kraim said, describing messages of sympathy, appreciation and personal testimonials about the company’s products.
What struck him most were the offers of assistance.
“We got tons of messages from people willing to offer a hand,” he said. “‘How can I help? My uncle owns a dispensary. Let’s protest.’ People just coming in hot, trying to help in any way that they can, which is just so beautiful and so Jewish.”
Others began stocking up, taking advantage of the products’ long shelf lives. The company is even considering producing its popular kosher-for-Passover gummies early so customers can buy them before the ban takes effect.
For customers who rely on the products for more than recreation, but relief, Kraim worries about what will happen when home delivery is no longer an option.
He described phoning one of their biggest customers only to discover an elderly Jewish woman on the other end of the line. She told the team how much she relied on their products and how convenient home delivery was, particularly because multiple ailments and limited mobility made it difficult for her to get to a dispensary.
“We were tearing up by the end of the call,” Kraim recalled.
Gabrielle G, a Tokin’ Jew customer since 2024, who declined to give her last name, called the news “truly devastating for the Jewish stoner community.”
“Their Advent calendars were a highlight of my Jewish holidays,” she told the Forward. “I hope they find a solution because TJ feels like family.”
Regardless, TokinJew.com will continue selling accessories, apparel, home goods and Judaica, with plans to expand its offerings.
They’re also planning a gradual move into licensed dispensaries, beginning in New York and eventually New Jersey. But that involves developing separate production, distribution and regulatory requirements for each state, a daunting prospect for a company that spent years developing its national online operation.
“But us Jews are the masters of the pivot,” he pointed out. “We historically have troubles thrown our way, and we always have to figure out our next step.”
For a company whose product line is largely inspired by the Jewish calendar, the date of the new bill feels particularly poignant: The new restrictions are scheduled to take effect on December 11, the evening Jews around the world light the eighth and final Hanukkah candle, commemorating the miracle of a single day’s supply of oil burning for eight.
“We have our plan A, B and C,” Kraim said. “One of which is praying for a Hanukkah miracle.”
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Trump antisemitism official to visit Michigan synagogue weeks before midterms, backed by ZOA
(JTA) — DETROIT – The Trump administration’s antisemitism czar will speak to a Michigan synagogue on Wednesday for a Justice Department event that also doubles as a fundraiser for the state’s chapter of the Zionist Organization of America.
Leo Terrell, who chairs the administration’s Task Force to Combat Antisemitism, is attending on behalf of the department. The Justice Department touted the event on its website with a link to a ZOA registration page that solicits donations to become an event co-sponsor.
Federal ethics regulations restrict fundraising by government employees and prohibit the use of government property for unauthorized purposes, though they allow authorized official fundraising and certain official speeches at fundraising events.
Terrell is visiting Congregation Shaarey Zedek in Southfield, a Detroit suburb; the synagogue is also listed as a co-sponsor. Other co-sponsors include a local Jewish high school, Mothers Against College Antisemitism and pro-Israel advocacy groups.
It comes weeks before the midterm elections, in which rhetoric on Israel and Jewish safety from the state’s Democratic Senate candidate Abdul El-Sayed has put local Jews on edge.
The Justice Department is billing the event as the first stop on Terrell’s “American Tour Against Hate,” adding, “All faiths and backgrounds welcome.” Terrell will be in conversation with Mort Klein, national head of ZOA, a usual stalwart Trump supporter who has broken with the president at times on Iran policy.
On its registration page for the event, ZOA Michigan notes that it “brings the Department of Justice directly into dialogue with Michigan’s Jewish community.”
ZOA Michigan also alluded to current tensions between the state’s Jewish community and El-Sayed.
“Antisemitism is reaching across Michigan — in schools, in public spaces, and among political candidates,” the event page reads. “Confronting it requires our community to stand together.”
The ZOA is a hawkish pro-Israel organization that backs the West Bank settlement movement and Israeli right wing government policies. In the U.S., it has also endorsed some of Trump’s restrictive immigration policies.
Federal tax law prohibits tax-exempt houses of worship from supporting or opposing political candidates, but Trump has sought to loosen the restrictions.
Rabbi Aaron Starr, of Shaarey Zedek, told the Jewish Telegraphic Agency that the Conservative congregation’s co-sponsoring of the event should not imply that it was endorsing one candidate over another.
“We are looking forward to working with anybody and everybody who wants to combat hate, whether that hate is antisemitism, Islamophobia, homophobia, racism or any other form of hate,” Starr said. He added that the congregation would soon welcome Jewish Democratic Sen. Elissa Slotkin for a veteran’s Shabbat.
Starr said the synagogue became a sponsor because it had been approached by ZOA to serve as an event host. “We’re mostly just serving as a venue for the event,” he said, adding that he personally would not be there.
Terrell did not return a JTA request for comment on the event. But he has promoted it extensively on social media and had hinted at the talk, and the ZOA partnership, in a previous email he sent to JTA reporters.
“We hope to see everyone there making it clear hate has no place in America a.k.a the greatest country on Earth,” he wrote at the time. He also thanked ZOA Michigan “for their tireless work on bringing our powerful message into reality.”
ZOA Michigan’s executive director, Kobi Erez, told JTA the event was nonpartisan, but added that he was aware of voters planning to switch parties — an allusion to Democrats who are considering voting for Rogers.
“We are not planning to discuss particular candidates or tell anyone how to vote,” Erez said in an email.
“We do encourage people to examine candidates’ records and statements concerning the safety of the Jewish community and consider whether they will take antisemitism seriously,” he said. “We feel that Jewish safety is at stake now more than ever. We know people who, because of these concerns, plan to vote for a party they have never supported before, and we understand their position.”
Erez said that the point of the event was not fundraising. “We are accepting voluntary sponsorships and donations to help cover expenses and support our work, but the purpose of this evening is to confront antisemitism and connect the community with the Department of Justice,” he said.
Frankel Jewish Academy, a private Jewish high school in the Detroit suburb of West Bloomfield Township, is also listed as a co-sponsor of the Terrell event. Frankel leaders did not return a JTA request for comment.
Terrell, an attorney, former O.J. Simpson supporter and ex-Fox News contributor, is a senior counsel in the Justice Department’s civil rights division. In that role, he oversees antisemitism taskforces that include staffers from the departments of Justice, Education and Health and Human Services.
Terrell’s visit comes as Trump, and Republicans more broadly, see an opening for Michigan in the midterms, in part via the Jewish vote. Both Trump and Vice President JD Vance will be campaigning in Michigan in the coming days. During Vance’s previous stop in Michigan, he went after El-Sayed for his reaction to the Temple Israel attack earlier this year.
Hundreds of local Jews have signed a petition pledging to vote for El-Sayed’s GOP opponent, former U.S. Rep. Mike Rogers, over their fears of the Democrat’s “extremism” on Jews and Israel, including El-Sayed’s remarks earlier this year about the attack on Temple Israel in the state. He has since apologized for those comments.
A separate petition — spearheaded by Starr and other rabbis — outlines “non-negotiables” that some Jewish leaders have pushed El-Sayed and other candidates to agree to.
This article originally appeared on JTA.org.
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Latin Jews seek belonging and identity in a country where they feel excluded
(JTA) — Ziggy Valdez, a nonbinary Mexican Jew studying to become a rabbi, was born in Illinois and grew up moving around the country as the child of a Navy father, always attached to a Reform synagogue. Valdez, who uses they/them pronouns, has Mexican roots on both sides of the family and has been “physically brown since birth,” but latinidad and Chicano identity weren’t an active part of family life. Their father worked in the Navy, which according to Valdez’ was the biggest barrier between them and the Jewish world. They grew up with Ashkenazi traditions, even when it meant driving an hour from the base where they were stationed at the time to the synagogue.
Valdez went to 10 different schools between preschool and senior year of high school.In many, they often felt excluded. “The kids at school who were also from Mexican families were not Jewish, and at some points in my adolescence, told me I wasn’t actually Mexican because I was Jewish and not Catholic,” Valdez told the Jewish Telegraphic Agency. “At times, my identity as Mexican felt like a source of shame for my family, Valdez said.”
The family would occasionally spend Christmas Day in Bakersfield, California with Valdez’s abuelo, or grandfather, where he would “cook the best mole ever made, including fresh tortillas.” But other than that they did not participate in Mexican culture.
Valdez heard about Jewtina & Co. (pronounced Jewtina y Co.), a national community of Latin Jews. After moving to Los Angeles two years ago, they joined the educators’ cohort of Jewtina’s Puentes national leadership fellowship, which has alumni across six cohorts, according to Violeta Stolpen, Jewtina & Co.’s Director of Operations.
“We were given the time and space to sit with that miracle of an experience, to be in a room with each other talking about the loneliness of growing up a Latin Jew, and being grateful that, thanks to the Jewtina, we weren’t alone anymore,” Valdez told JTA.
Jewtina & Co. was founded during Latin Heritage month in 2019 by Analucía Lopezrevoredo, a Peruvian Jew who moved to California with her family when she was five years old. A sociologist by training, she grew up surrounded by vibrant Latin and Jewish communities and began calling herself a Jewtina early on.
The idea of Jewtina crystallized in 2018, when she applied for a fellowship focused on global Jewry. “It started with a question I had carried on since childhood: Where do people like me get to be whole?” she told JTA. It is a way for Jewish immigrants from Latin America in the U.S. to express their conflicting and overlapping Jewish and Latinos identities publicly. Its members are mixed-couple children of Latin American descent, Latin immigrants who converted to Judaism, Latin Americans who were adopted into an American family and many more shades of Jewish Latinhood.
Lopezrevoredo calls Jewtina part of a Jewish and Latin diaspora, which comes with its own identity challenges. Latino communities in the U.S. are heavily Catholic, so there is little space in these immigrant enclaves for members of other faiths. Latino Jews feel excluded from Mexican, Peruvian and other communities. But there is also discrimination of Jewtina members from Latin American Jewish communities. U.S.-based demographic categories, such as Latinos and Jews, can create exclusionary identities that do not fit neatly with complex migration paths.
“There is no single Latin Jewish experience” Loperevoredo said, “just as there is no single Jewish one. But one experience we hear again and again is the feeling of having to explain oneself.”
No national study has measured the size or demographic makeup of the Latin Jewish community in the U.S., according to Jewtina & Co.’s Director of Research and Evaluation David McCarty-Caplan, who holds a Ph.D. in social work. The closest estimate comes from “American Jewish Population Estimates 2020: Summary & Highlights,” a 2021 report by Brandeis University’s American Jewish Population Project. It found that about 6% of Jewish adults in the U.S. identify as Hispanic out of 7.6 million.
To make Latin Jews more visible and better understood, McCarty-Caplan is developing a national study of Latin Jewish community and identity in the U.S. The partners are Brandeis University’s Initiative on the Jews of the Americas and its Cohen Center for Modern Jewish Studies, along with Universidad Hebraica in Mexico. He said it will be the first study of its kind.
McCarty-Caplan says he has felt deeply disconnected from his Latino origins and out of place in predominantly white Jewish spaces. He was born in Bogotá, Colombia, and adopted at 3 months old by a white American Jewish family. In 2019, he met founder Lopezrevoredo in a Jews of Color cohort of Bend the Arc’s Selah Leadership Fellowship. That’s where he learned about her work with Jewtina & Co.
“It felt like meeting her, and finding Jewtina was the first time I felt fully seen and valued as a Latino, a Jew, and an adoptee all at once,” he said.
Members of Jewtina & Co. are often a mixture of identities. Founding member and Director of Education Kimberly Dueñas’ mother is an Ashkenazi Jew born and raised in Los Angeles, with family roots in Ukraine and Poland. Her father was born and raised in El Salvador, in a rural farming community. Through his side, she has converso Sephardic Jewish — a convert to Christianity or a descendant thereof — and Indigenous Mesoamerican ancestry. He met Dueñas’ mother at a Passover seder in Orange County, California where Dueñas grew up.
“I know personally what it’s like to feel like I have to choose which identity to lead with,” said Dueñas who facilitates Puentes.
According to director of operations Stolpen, the organization ran 58 programs in 2025, 43 in person and 15 virtual, with 2367 participants. So far in 2026, it has held 47 programs and events with more than 1,200 participants, according to McCarty-Caplan.
The organization faces a harder climate than the one it was born into. When Jewtina & Co. emerged in 2019 and 2020, director of research McCarty-Caplan said there was a surge of support for groups working with multiracial Jewish communities. That support has since receded since the beginning of President Donald Trump’s second term. Since “the events in Israel-Palestine on Oct. 7th, significant attention and resources have moved away from supporting organizations like Jewtina,” he added, referring to the war launched in 2023 after Hamas raided communities inside Israel.
Oct. 7 also changed things for Jewtina & Co.’s members. “Many Latin Jews have encountered antisemitism in spaces where they once felt cultural or political kinship,” Lopezrevoredo said, “while also entering Jewish spaces where conversations about race, immigration, Latin America or the diversity of Jewish experience can feel constrained.”
Dueñas said one of the organization’s biggest challenges is responding in real time to what its community needs. “We are navigating fear around immigration, ICE raids and deportation within our Latino communities, while also experiencing the rise of antisemitism and the ripple effects of the war in Israel and Palestine within our Jewish communities,” she told JTA.
Jewtina & Co. has responded with spaces for processing, healing and spiritual support, along with mental health resources, rabbinic wisdom and Know Your Rights programming.
“A Jewish family can carry memories of Poland, Syria, Turkey, or Morocco, become deeply Argentine, Mexican, Brazilian, or Cuban over generations, and later become Latino in the United States.” Lopezrevoredo said ”None of those layers cancels the others.”
This article originally appeared on JTA.org.
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