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Dr. Lorne Brandes on how the COVID-19 pandemic has affected how he now delivers medicine and some of the latest findings about the coronavirus

Dr. Lorne Brandes

By JON VAN DER VEEN

To further understand the challenges and changes resulting from the pandemic, The Jewish Post & News has reached out to different members of the community to see how their lives have been impacted.
We contacted Dr. Lorne Brandes, who has had a long career as an oncologist, but who, upon retiring from that specialty, has been working as a practicing internist at Eaton Place Medical Centre. We wanted to know how Dr. Brandes has adapted to the restrictions imposed upon doctors such as him.

Lorne Brandes received his M.D. from the University of Western Ontario in 1968, followed by a Fellowship in Internal Medicine from the Royal College of Physicians and Surgeons of Canada. He became a professor at the University of Manitoba in 1975, where he conducted cancer research and was a tenured professor in the Faculty of Medicine, while also being an oncologist at CancerCare Manitoba.

I asked Dr. Brandes how Covid-19 has affected his work.
He said that he is now primarily working from home, but that the Eaton Place clinic remains open with several of his colleagues choosing to go into the office a couple times a week. Dr. Brandes said, “It’s an interesting transition but one that has worked out well.”
He went on to say that it’s been very easy to work from home since he has the same clinical programs on his computer that are at the office.
“I can do consults with other doctors from home, order x-rays, CT scans, MRIs, new prescriptions, old prescriptions, and blood work, I can do it all,” he explained. The only thing Dr. Brandes said he couldn’t conduct from his house were in-house examinations, but even that isn’t too much of a problem, he said, because most of his patients are follow-ups, so it’s quite easy to do appointments over the phone.

I asked him how then he was handling patient examinations, and if he was just treating the phone consultations as pre-screenings?
Dr. Brandes answered that since most people nowadays have a cellphone, they can take a picture of any physical findings like a rash or lump and send that to him. He could then assess the image and make the proper referrals or order any tests.
He offered the following example how a phone screening could work: “If I’m managing a patient with diabetes, I can send them to the lab to get their bloodwork done a couple of days before the phone call and then I have it to go over with them. I can make any changes to their medication that way. A very high percentage of patients have their own blood pressure gauge at home and to several of them I have recommended that if they are willing to go buy one, they’re only $70 now. They can therefore measure their blood pressure at home, take several readings, and then we can discuss it over the phone, and I know how their blood pressure is doing and if their medication is working well.”
Dr. Brandes also noted that it’s much easier for people to consult online rather than in person at the clinic because patients don’t need to drive downtown and wait in a lobby for him. As a result, he added, almost everyone keeps their appointments over the phone and they are much less likely to reschedule or cancel, especially since many people are staying at home for a large portion of the day during the pandemic.

At that point in the interview we began to talk about the virus itself, and the possibility of a vaccine being introduced in the near future. Dr Brandes suggested that we’ll be very lucky to have a vaccine by halfway through next year, but that he remains optimistic because there are multiple high-tech vaccines currently in the works. Yet, he also issued a warning that “There are a lot of unknowns… no vaccine is 100% effective, and that vaccines are less effective in older people.”
However, he also said that, similar to a flu vaccine – which is by no means 100% protective, a coronavirus vaccine doesn’t necessarily need to protect you from getting infected – it just needs to stop you from getting deadly sick. Moreover, whether a vaccine “will give long term protection, or if we’ll have to take it every year we just don’t know yet.”

I mentioned that I had read an Oxford study about the effect of the virus on twins. According to that study fraternal twins showed a greater variation in infections, whereas identical twins were likely either both be to be immune to the virus or both identically susceptible to the coronavirus, which suggested a genetic predisposition to becoming infected.
Dr. Brandes agreed, saying: “That makes a lot of sense. We know that you do inherit your genes and they do determine your immune response to a significant degree and that variations in the immune response may well be genetically determined.”
Dr. Brandes then offered this observation about susceptibility to the virus: Apparently studies show that people with Type A blood have a higher chance of getting a severe case of COVID-19. However, Dr. Brandes added the caveat that the blood type itself may not be responsible.
“Is it the blood type itself?” he wondered. “Not necessarily,” he continued, “because the blood type gene is intimately linked with what we call the HLA gene. Those are the tissue genes that are linked to the immune system. So, there’s no question, it’s very clear that there are huge differences in how people react to this virus, that are very likely, in a major part at least, linked to their immune system, and how they’ve inherited their immunity.”

I then asked about “pre-existing conditions” and which conditions specifically pose the greatest dangers.
Dr Brandes replied, “There is a clear link between worse outcomes in patients who have hyper-tension, high blood pressure, diabetes and so on. The high blood pressure link is very interesting because the receptor on the cells to which the virus links is called the ACE2 receptor and many of the drugs that are used to treat blood pressure bind to that receptor. So, whether having high blood pressure itself is causing a severe interaction with the virus and that receptor, or being on drugs which interact with that receptor, may modulate in a good way or bad way… these are the things we are learning.”
He went on to say that “We also know some young people have died from the virus with no apparent pre-existing conditions so that maybe takes it back to something in their immune system being wonky.”

 

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Features

Hacker and Fraud Prevention for Online Gambling Profiles

Safeguard your online casino & sports betting accounts from cyber threats

Follow these 10 vital steps to reinforce your online gambling profile by enabling two-factor authentication, using VPNs, unique passwords and more.

With the global online gambling market projected to reach over $100 billion by 2026, securing your online casino and sportsbook accounts is more critical than ever. As digital wallets swell with winnings so too does the motivation for cybercriminals to steal credentials and loot accounts.

#1. Activate Two-Factor Authentication

Topping the list is two-factor authentication (2FA) – requiring two credentials to login instead of one at FanDuel. Often this entails providing your password plus a one-time code sent via SMS or email.

Per an Oracle study, implementing 2FA would have thwarted 99% of historical cyber attacks that involved stolen credentials.

Most regulated online gambling sites offer 2FA, accessible under account settings. Turn it on immediately for stronger defense.

#2. Never Reuse or Recycle Passwords 

A cardinal sin is recycling the same password across multiple sites or services. Once one account is breached, cyber thieves can access more accounts using that same password.

To avoid this, every account deserves a unique, strong password. For simplicity, utilize a password manager app to randomly generate and store site-specific passwords.

#3. Install a VPN for Public Wi-Fi Access 

When playing online casino games on shared/open wireless networks, your data flows openly and risks interception. That’s where virtual private networks (VPNs) come in.

VPNs encrypt all network traffic to and from your device. This protects your gambling activity and account credentials from Wi-Fi eavesdroppers. VPNs also disguise your IP address.

Some top-rated services include NordVPN, ExpressVPN and CyberGhost.

#4. Keep Software Updated & Run Anti-Virus Scans 

You must keep computers and mobile devices updated with the latest OS and security patches. Postponing critical updates leaves open dangerous holes that malware exploits.

Likewise run reputable anti-virus scans to catch viruses attempting to infiltrate systems and spy on login credentials for financial accounts.

#5. Verify the Security & Encryption of Sites 

When signing up at online betting sites and casinos, verify the legitimacy of their security measures:

  • Confirm the address starts with HTTPS, not HTTP
  • Check that data transmissions are encrypted using at least 128-bit SSL
  • Ensure site has proper licensing
  • Review privacy policy for data storage and sharing

Reputable sites will display trust badges from companies like Norton and TrustE.

#6. Avoid Account Sharing 

While tempting to give friends or relatives access to funded accounts, sharing login credentials is extremely risky. You lose control over deposits/withdrawals while exposing yourself to potential theft.

Instead, gift deposits to other player accounts or refer them to open their own secure accounts.

#7. Beware Account Takeover Scams 

Exercise caution if contacted unexpectedly about unusual account activity. Savvy scammers will pretend a breach occurred to trick you into handing over your username and password.

If concerned about account integrity, directly access the site yourself and contact customer support – don’t click any links in unsolicited emails.

#8. Monitor Financial Statements

Carefully review online betting account and credit card statements to detect unauthorized transactions right away. Dispute unrecognized activity ASAP to limit losses.

For further vigilance, some banks offer real-time purchase alerts via email or SMS.

#9. Don’t Save Payment Info 

Saving credit card or e-wallet details on gambling sites for faster future deposits also expedites withdrawals – by you and potentially hackers.

Instead, manually enter payment info each time to contain potential damage from any account infiltration.

#10. Create a Secure Email 

A strong yet oft-overlooked defense is creating a secure email account strictly for gambling transactions. Keep it completely separate from your personal email to isolate threats.

Use a nickname, enable 2FA and establish a strong password using special characters, numbers, case changes and 15+ letters.

Table: Comparison of Top VPNs for Online Gambling Site Security

VPN ServiceEncryption StandardNumber of Server LocationsAllows P2P TrafficNumber of Simultaneous ConnectionsMoney Back Guarantee
NordVPNAES 256-bit5400+Yes630 days
ExpressVPNAES 256-bit3000+Yes530 days
CyberGhostAES 256-bit7400+Yes745 days

Fortify Your Online Gambling Fortress 

As online casinos and sportsbooks explode in popularity, no player is immune to the growing plague of cyber fraud and account theft.

Guard your profile by enabling two-factor authentication, setting strong passwords, installing critical software updates and more. Also research site security measures and payment options.

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Features

Vital Role of True Randomness in Modern Computing

The critical need for true randomness in cryptography, simulations, and more

True randomness is essential for encryption, statistical sampling, simulations, and more computing applications to work effectively. We explore why.

The concept of randomness often evokes thoughts of unpredictability and chance occurrences. However in the world of computing, having access to true randomness is vital for many critical applications to function properly. Without the ability to generate random values and data, key aspects of modern technology simply would not work reliably.

In this article, we will explore what constitutes true randomness from a computational perspective, why it is crucially important, and some of the ways that software and hardware attempt to produce randomness reliably. Gaining insight into this topic highlights the dependence much of digital functionality has on the availability of non-deterministic, uniformly distributed random data.

What Makes Randomness “True”?

For data to be considered truly random from an information theory perspective, values must satisfy key mathematical and statistical qualities, for example at Lucky Seven Casino. True randomness implies meeting three core criteria:

  • Uniform distribution — All potential values have an equal probability of occurring so that no bias exists towards certain numbers.
  • Independence — The value at any position does not relate to or depends on values at other positions. Previous numbers do not influence future ones.
  • Unpredictability — Knowing some values provides no useful information to predict other values. Guessing upcoming numbers is mathematically impossible.

Hence, true randomness requires generated data featuring high entropy (information density) with no observable patterns or correlations over any length or time period analyzed. Values must pass various statisticatests of randomness to qualify. True randomness exists only in specific natural phenomena scientists believe exhibit fundamental uncertainty such as radioactive decay. Computational methods can attempt to produce randomness but technically generate only an approximation usually called pseudo-randomness. However for many practical purposes, computationally generated randomness proves sufficient if it passes robust statistical testing.

Why True Randomness Matters Cryptography 

Arguably, the area with the most crucial dependence on true randomness is cryptography. All modern encryption technologies require random number generation to ensure security. Encryption systems work by utilizing random numbers for:

  • Key generation
  • Initialization vectors
  • Salts
  • Nonces
  • Padding

Any bias, predictability or correlation within random values used for the above purposes significantly compromises encryption protocols and introduces vulnerabilities. With trillions of dollars transferred online daily and vast amounts of sensitive data stored digitally, safeguarding cryptography requires high-quality random number generation rooted in solid entropy sources.

Simulations & Modeling 

Outside of security, many more computing applications need randomness to operate correctly per their design intent. Monte Carlo simulations extensively utilize randomness to model complex real-world behaviors by running many iterations with differing random inputs. Financial analysis, climate modeling, nuclear reactions and molecular behavior represent common Monte Carlo simulation applications.

Games, Artificial Intelligence & Machine Learning 

Gaming, AI and ML commonly incorporate randomness to increase variation, introduce unpredictability, and improve realism. For example, non-player characters in video games use randomness for movement, dialog and behavior to feel more lifelike and less robotic. AI/ML leverage randomness to train networks more thoroughly against a wider possibility space and build more resilient models less prone to biases.

Generating True Randomness via Hardware 

Given the pervasive need for genuine randomness across computing, how do software and hardware reliably produce it? Most systems today use either specialized hardware random number generators or hybrid combinations of hardware and software.

Hardware options utilize the inherent randomness within low-level physical phenomena to produce entropy. Different techniques for generating randomness exist but most hardware implementations focus on three main sources:

  1. Thermal Noise
  2. Semiconductor Quantum Physics
  3. Chaotic Oscillator Outputs
Generator TypeDescription
Thermal NoiseAmplifies and extracts random electrical noise from resistor thermal vibrations
Quantum PhysicsLeverages quantum mechanical properties like photon emission timing from LEDs/lasers
Chaotic CircuitsUses unpredictable oscillator circuit outputs from chaos theory

Semiconductor-based solutions can generate high bitrates up to 5Gbps using compact modern chip fabrication allowing extensive harvestingof entropy. However these sources derive from complex, random physical processes proving impossible to predict or fully model mathematically. This unpredictability provides excellent entropy quality unattainable via software algorithms alone.

Most general-purpose computers now integrate random number generators within CPUs allowing applications access to decent hardware-based random data. For the highest security use cases, dedicated standalone hardware random number generators exist exceeding >100Gbps speeds. Hence accessing genuine randomness is available today even on common computing devices.

Cryptographically Secure Pseudo-Random Number Generators 

While hardware mechanisms utilize hard-to-predict physical phenomena to produce randomness, software solutions must take a different approach. Algorithmically-generated randomness cannot achieve true randomness from a physics perspective. However clever mathematical techniques like cyclical algorithms can generate randomness passing many statistical tests of randomness within their output bit length limits.

Cryptographically secure pseudo-random number generators (CSPRNG) serve as the premier software-based method for generating randomness. CSPRNGs work by repeatedly applying cryptographic primitives like hash or cipher functions on initial random seed values. This process produces a chain of output bits not reproducible without the original seed key. Leading CSPRNG algorithms include:

  • Hash_DRBG
  • HMAC_DRBG
  • CTR_DRBG

Software libraries implement these CSPRNGs so developers can integrate quality randomness into applications with proper seeding. Seeding establishes the initial starting point for randomness generation using an entropy source like hardware random number generators or timing variability.

CSPRNGs allow the production of vast quantities of randomized data for any purpose needed. Compared to hardware mechanisms limited by physics on maximum speeds, algorithms scale boundlessly in the bits created as long as adequate computational power exists.

Yet key differences between software and hardware randomness remain. While CSPRNG outputs pass statistical testing and contain no observable patterns, their pseudo-randomness means given the same seed, the exact same value sequence will generate each time. Also, if a CSPRNG algorithm or implementation has flaws, adversaries could predict and exploit output resulting in compromised security. Still, with proper cryptographic design and regular reseeding, CSPRNGs provide quality randomness for most software needs.

Conclusion

From the above exploration, we see true randomness plays a pivotal role across computing – from cybersecurity to simulations and beyond. While no substitutes for true physically-derived entropy exist, modern hardware and hybrid hardware-software solutions provide abundant randomness for practical usage.

However as computing continues evolving with new technologies like quantum, ensuring high-quality randomness generation tackles emerging information security and system reliability challenges. Access to ample true randomness stands necessary now for current computing functionality and lays the foundation for future innovation.

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Features

News from Israeli hotels

Roy Avidor new GM at The Ritz-Carlton, Herzliya

Introduction: The current wars in Gaza and Lebanon have had a disastrous effect on Israeli tourism. Recently we were contacted by a friend in the advertising business in Israel who asked us whether we would help to promote a couple of well-known Israeli hotels – who are hoping for a huge rebound in bookings once the wars come to an end.

Here is news about two leading Israeli hotels:

Mr. Roy Avidor is the new GM at The Ritz-Carlton, Herzliya.

We are delighted to welcome Roy Avidor as the new General Manager of The Ritz-Carlton, Herzliya!

Roy brings over a decade of leadership in the international hospitality industry, with a proven track record of operational excellence.

Most recently, Roy served as Director of Operations at the Sheraton Grand Tel Aviv, where he oversaw daily operations across multiple departments, always ensuring the highest standards of service. Prior to that, he held management positions at Celebrity Cruise Line and Isrotel Hotel Chain.

Roy’s extensive background in luxury hospitality, combined with his passion for service, makes him the perfect addition to our team and to his newest position as General Manager.

Boaz Elani Appointed General Manager of Sheraton Grand Hotel Tel Aviv

Boaz Elani has been named the new General Manager of the Sheraton Grand Hotel Tel Aviv, a prestigious property within the global luxury Marriott portfolio.

Bringing extensive expertise in luxury hospitality, Boaz most recently served as the General Manager of the Ritz-Carlton Herzliya, also part of the Marriott group. During his three-year tenure, he successfully navigated the hotel through two major challenges: the COVID-19 pandemic and the conflict in Israel. His steadfast dedication to exceptional service significantly enhanced guest satisfaction, solidifying the hotel’s reputation as a premier destination.

“I am honored by Marriott’s trust in me and thrilled to join the Sheraton Grand Tel Aviv team,” said Boaz. “This hotel holds a distinguished place as one of Israel’s finest and most iconic. Following its comprehensive renovation, we are committed to delivering unmatched experiences for our guests and continuing its tradition of excellence.”

The Sheraton Grand Tel Aviv, overlooking the Mediterranean, features 320 beautifully redesigned rooms, including premium, deluxe, and club accommodations, along with luxurious suites. Guests staying in club-level rooms enjoy exclusive access to the 18th-floor lounge, offering breathtaking sea views. The recent renovations incorporate modern aesthetics with natural, seaside-inspired materials, creating a serene and inviting ambiance.

The hotel boasts a range of world-class amenities, including a newly updated beachfront pool, a popular sushi bar open to both guests and the public, and a renowned gourmet breakfast. Its versatile meeting spaces and state-of-the-art conference halls have garnered international acclaim, earning it the 2024 World MICE Award for Best Event and Conference Hotel.

In line with Marriott’s global commitment to sustainability, the Sheraton Grand Tel Aviv has held Green Key Certification since 2014, highlighting its dedication to environmentally responsible practices.

With Boaz Elani at the helm, the Sheraton Grand Tel Aviv is poised to further elevate its status as a premier destination for both leisure and business travelers.

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